Background Tsetse flies are the cyclical vectors of both human and animal diseases. Kenya’s commitment to eradicate tsetse and trypanosomiasis dates to the 1980s through various control approaches which were spearheaded by the African Union.
Ferdinard Adungo +3 more
doaj +1 more source
This study aimed to identify trypanosomes infecting cattle in Malawi in order to understand the importance of cattle in the transmission dynamics of Human African Trypanosomiasis (HAT) and Animal African Trypanosomosis (AAT).
Marsela Megasari +8 more
doaj +1 more source
Accuracy of five algorithms to diagnose gambiense human African trypanosomiasis. [PDF]
Algorithms to diagnose gambiense human African trypanosomiasis (HAT, sleeping sickness) are often complex due to the unsatisfactory sensitivity and/or specificity of available tests, and typically include a screening (serological), confirmation ...
Francesco Checchi +19 more
core +2 more sources
A literature review of economic evaluations for a neglected tropical disease : human African trypanosomiasis ("sleeping sickness") [PDF]
Human African trypanosomiasis (HAT) is a disease caused by infection with the parasite Trypanosoma brucei gambiense or T. b. rhodesiense. It is transmitted to humans via the tsetse fly.
Sutherland, C. S. +16 more
core +1 more source
African trypanosomiasis in travelers returning to the United Kingdom. [PDF]
Two returning safari tourists with African trypanosomiasis were admitted to the Hospital for Tropical Diseases, London, in a 3-day period, compared with six cases in the previous 14 years.
Bailey, J Wendi +17 more
core +1 more source
Identification of sVSG117 as an immunodiagnostic antigen and evaluation of a dual-antigen lateral flow test for the diagnosis of human african trypanosomiasis [PDF]
The diagnosis of human African trypanosomiasis (HAT) caused by Trypanosoma brucei gambiense relies mainly on the Card Agglutination Test for Trypanosomiasis (CATT). There is no immunodiagnostic for HAT caused by T. b. rhodesiense.
Sastry Lalitha +20 more
core +2 more sources
Kynurenine pathway inhibition reduces central nervous system inflammation in a model of human African trypanosomiasis [PDF]
Human African trypanosomiasis, or sleeping sickness, is caused by the protozoan parasites <i>Trypanosoma brucei rhodesiense</i> or <i>Trypanosoma brucei gambiense</i>, and is a major cause of systemic and neurological disability ...
Barrett, M.P. +4 more
core +1 more source
Implications of heterogeneous biting exposure and animal hosts on Trypanosomiasis brucei gambiense transmission and control [PDF]
The gambiense form of sleeping sickness is a neglected tropical disease, which is presumed to be anthroponotic. However, the parasite persists in human populations at levels of considerable rarity and as such the existence of animal reservoirs has been ...
Chitnis, Nakul +5 more
core +2 more sources
Towards the Atlas of human African trypanosomiasis [PDF]
Background Updated, accurate and comprehensive information on the distribution of human African trypanosomiasis (HAT), also known as sleeping sickness, is critically important to plan and monitor control activities.
Cecchi Giuliano +28 more
core +1 more source
Biological and pharmacological investigations of novel diamidines in animal models of human African trypanosomiasis [PDF]
"African sleeping sickness, also called human African trypanosomiasis (HAT), results from the infection of humans with either of two protozoan parasites, Trypanosoma brucei gambiense and T. b. rhodesiense. HAT is transmitted by tsetse flies (Glossina spp)
Kibuthu, John Thuita
core +1 more source

