Results 51 to 60 of about 2,882,714 (182)

Haemoparasitic Infections in Cattle from a Trypanosoma brucei Rhodesiense Sleeping Sickness Endemic District of Eastern Uganda

Tropical Medicine and Infectious Disease, 2020
We carried out a baseline survey of cattle in Kaberamaido district, in the context of controlling the domestic animal reservoir of Trypanosoma brucei rhodesiense human African trypanosomiasis (rHAT) towards elimination.
Enock Matovu, Claire Mack Mugasa, Peter Waiswa, Annah Kitibwa, Alex Boobo, Joseph Mathu Ndung’u   +5 more
doaj   +1 more source

Therapeutic Efficacy of Orally Administered Nitrofurantoin against Animal African Trypanosomosis Caused by Trypanosoma congolense Infection

Pathogens, 2022
Animal African trypanosomosis (AAT) leads to emaciation and low productivity in infected animals. Only six drugs are commercially available against AAT; they have severe side effects and face parasite resistance.
K. Suganuma, D. N'Da, Kenichi Watanabe, Yusuke Tanaka, Ehab Mossaad, Afraa Elata, N. Inoue, S. Kawazu   +7 more
semanticscholar   +1 more source

Trypanosomiasis vector control in Africa and Latin America. [PDF]

, 2008
Vectors of trypanosomiasis - tsetse (Glossinidae) in Africa, kissing-bugs (Triatominae) in Latin America - are very different insects but share demographic characteristics that render them highly vulnerable to available control methods.
Schofield, Chris J, Kabayo, John P, Schofield Chris J, Kabayo John P   +3 more
core   +1 more source

Targeted protein degradation might present a novel therapeutic approach in the fight against African trypanosomiasis

European Journal of Pharmaceutical Sciences, 2023
African trypanosomiasis (AT) is a hemoparasitic disease caused by infection with African trypanosomes and it is prevalent in many sub-Saharan African countries, affecting both humans and domestic animals.
A. U. Danazumi, Ibtida Tabassum Ishmam, Salisu Idris, M. Izert, E. Balogun, M. Górna   +5 more
semanticscholar   +1 more source

First PATTEC consultative workshop on strategies, technical advances and partnerships in tsetse and trypanosomosis management

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 2015
Tsetse and trypanosomiasis (T&T) remain endemic in many countries, although many efforts have been made in recent decades within the framework of the Pan-African Tsetse and Trypanosomiasis Eradication Campaign (PATTEC) Initiative, and despite progress ...
Hassane H. Mahamat
doaj   +1 more source

Genomic evidence of sex chromosome aneuploidy and infection-associated genotypes in the tsetse fly Glossina fuscipes, the major vector of African trypanosomiasis in Uganda

Infection, Genetics and Evolution, 2023
The primary vector of the trypanosome parasite causing human and animal African trypanosomiasis in Uganda is the riverine tsetse fly Glossina fuscipes fuscipes (Gff). Our study improved the Gff genome assembly with whole genome 10× Chromium sequencing of
N. Saarman, Jae Hak Son, Hongyu Zhao, Luciano V. Cosme, Yong Kong, Mo Li, Shiyu Wang, B. Weiss, R. Echodu, Robert Opiro, S. Aksoy, A. Caccone   +11 more
semanticscholar   +1 more source

Human African trypanosomiasis [PDF]

, 2009
Human African trypanosomiasis (sleeping sickness) occurs in sub-Saharan Africa. It is caused by the protozoan parasite Trypanosoma brucei, transmitted by tsetse flies.
Chappuis, F, Blum, J., Brun, R, Chappuis, F., Brun, R., Burri, C, Burri, C., Blum, J   +7 more
core   +1 more source

Prevalence and under-detection of gambiense human African trypanosomiasis during mass screening sessions in Uganda and Sudan [PDF]

, 2012
BACKGROUND: Active case detection through mass community screening is a major control strategy against human African trypanosomiasis (HAT, sleeping sickness) caused by T. brucei gambiense.
Haydon Daniel T, Chappuis, F., Cox, A.P., Cox Andrew P, Checchi Francesco, Haydon, D.T., Priotto Gerardo, Priotto, Gerardo, Checchi, Francesco, Chandramohan, Daniel, Priotto, G., Haydon, Daniel T, Cox, Andrew P, Checchi, F., Chandramohan, D., Chappuis, François, Chappuis François, Chandramohan Daniel   +17 more
core   +1 more source

Population genetics of tsetse, the vector of African Trypanosomiasis, helps informing strategies for control programs

Peer Community In Zoology, 2023
Human African Trypanosomiasis (HAT), or sleeping sickness, is caused by trypanosome parasites. In sub-Saharan Africa, two forms are present, Trypanosoma brucei gambiense and T. b. rhodesiense , the former responsible for 95% of reported cases.
H. Michael G. Lattorff
semanticscholar   +1 more source

Safety, pharmacokinetic, and efficacy studies of oral DB868 in a first stage vervet monkey model of human African trypanosomiasis [PDF]

, 2013
There are no oral drugs for human African trypanosomiasis (HAT, sleeping sickness). A successful oral drug would have the potential to reduce or eliminate the need for patient hospitalization, thus reducing healthcare costs of HAT.
Arlene S. Bridges (301008), Shelley Ching, Bridges, Arlene S., Raymond E Mdachi, Brun Reto, Wang Michael Zhuo, Wang, Michael Zhuo, Wolf, Kristina K., Ching, Shelley, Arlene S Bridges, Mutuku James N., Murilla, Grace A., Paine, Mary F., Boykin, David W., James N Mutuku, Richard R Tidwell, Mohamed A Ismail, John K. Thuita (148377), Liu, Qiang, Tidwell, Richard R., Hall, James E., Mary F. Paine (148396), John K Thuita, Bridges Arlene S., Ismail Mohamed A., Mdachi, Raymond E., Qiang Liu (166143), Mdachi Raymond E., David W. Boykin (148406), Reto Brun, Reto Brun (41511), Ching Shelley, Hall, James Edwin, Shelley Ching (148404), Tidwell Richard R., Chen, Yao, Mohamed A. Ismail (418629), Boykin David W., Mutuku, James N., James Edwin Hall, Qiang Liu, Grace A Murilla, Hall James Edwin, Raymond E. Mdachi (148398), Mary F Paine, Liu Qiang, Kristina K. Wolf (418627), Michael Zhuo Wang, Thutia, John K., David W Boykin, Yao Chen (149006), Grace A. Murilla (148401), Ismail, Mohamed A., Michael Zhuo Wang (418631), Murilla Grace A., Wolf Kristina K., Kristina K Wolf, James Edwin Hall (418630), Thuita John K., James N. Mutuku (418628), Brun, Reto, Yao Chen, Thuita, John K., Richard R. Tidwell (148409), Paine Mary F., Chen Yao   +65 more
core   +2 more sources