Results 101 to 110 of about 2,230,364 (263)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Consumers' Willingness to Pay for Additional Information on Food Quality and Safety [PDF]

open access: yes
Most quality properties of food products can be considered as credence characteristics, quality of which cannot be inferred before the purchase, and sometimes not even after the purchase.
Kola, Jukka, Latvala, Terhi
core   +1 more source

How can organic agriculture contribute to long-term climate goals? [PDF]

open access: yes, 2013
The EU countries aim to reduce their emissions of greenhouse gases (GHG) by 80-95% by 2050 (European Commission, 2011). The food sector accounts today for 25% of Swedish greenhouse gas emissions, most of which arise in agricultural production, so there ...
Röös, E.   +3 more
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Control tools to detect processed animal proteins in feed and in animal by-products: specificity and challenges [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2009
This paper reviews the current situation with regard to a total feed ban on the use of processed animal proteins in feed for meat producing animals within the EU. The scientific aspects surrounding the development of control tools are discussed.
Woodgate SL.   +3 more
doaj  

Risk to public and/or animal health of the treatment of dead‐in‐shell chicks (Category 2 material) to be used as raw material for the production of biogas or compost with Category 3 approved method

open access: yesEFSA Journal, 2015
In 2011, EFSA assessed the risk posed by the possible use of dead‐in‐shell chicks for the production of processed pet food. In 2014, the European Commission asked for an update on the risk posed by the same material but as raw material for the production
EFSA Panel on Biological Hazards (BIOHAZ)
doaj   +1 more source

The future of the Dutch egg processing industry [PDF]

open access: yes
This research examines the competitiveness of the Dutch egg products industry, as well as the consequences of tightening up the laws concerning layer poultry on the competitive position of the Dutch egg production industry.
Cotteleer, Geerte   +2 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Scientific Opinion on Bioreduction application

open access: yesEFSA Journal, 2013
A method for on‐farm containment of animal by‐products (ABPs), called a ‘Bioreduction’ system, was assessed. The material for containment is of ovine origin and classified as a Category (Cat.) 1 ABP material.
EFSA Panel on Biological Hazards (BIOHAZ)
doaj   +1 more source

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