Results 141 to 150 of about 26,422,673 (403)

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

TSG101 depletion dysregulates mitochondria and PML NBs, triggering MAD2-overexpressing interphase cell death (MOID) through AIFM1-PML-DAXX pathway

Cell Death and Disease
Overexpression of mitotic arrest deficiency 2 (MAD2/MAD2L1), a pivotal component of the spindle assembly checkpoint (SAC), resulted in many types of cancer.
Yao Xi, Rui Xu, Shengnan Chen, Jiezhu Fang, Xiang Duan, Yidan Zhang, Guoli Zhong, Zhifei He, Yan Guo, Xinyu Li, Wenzhi Tao, Yang Li, Yan Li, Lei Fang, Yohei Niikura   +14 more
doaj   +1 more source

Modeling Animals in Clay the Passing of Taxidermy [PDF]

, 1904
Walter L. Beasley
openalex   +1 more source

Feeding and the Equilibrium Feeder Animal Price-Weight Schedule [PDF]

Feeder animal prices depend on fed animal prices, the biological growth technology, and feed costs. In addition, daily maintenance costs can be avoided through accelerated feeding.
Hennessy, David A.
core   +1 more source

A learning rule for place fields in a cortical model: theta phase precession as a network effect

, 2005
We show that a model of the hippocampus introduced recently by Scarpetta, Zhaoping & Hertz ([2002] Neural Computation 14(10):2371-96), explains the theta phase precession phenomena.
Bi, Booth, Burgess, Burgess, Diederich, Harris, Hertz, Huxter, Jensen, Lengyel, Li, Magee, Markram, Metha, O'Keefe, Personnaz, Scarpetta, Skaggs, Tsodyks, Wallenstein, Yamaguchi, Yamaguchi, Zugaro   +22 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Towards an Ethological Animal Model of Depression? A Study on Horses

PLoS ONE, 2012
Background Recent reviews question current animal models of depression and emphasise the need for ethological models of mood disorders based on animals living under natural conditions.
C. Fureix, P. Jego, S. Henry, lea lansade, M. Hausberger   +4 more
semanticscholar   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Antibody‐Mediated Immune Suppression to the Rh Factor: Animal Models Suggesting Mechanism of Action [PDF]

, 1968
William Pollack, J. G. Gorman, Henrik Hager, Vincent J. Freda, D Tripodi   +4 more
openalex   +1 more source

Identifying manifolds underlying group motion in Vicsek agents

, 2015
Collective motion of animal groups often undergoes changes due to perturbations. In a topological sense, we describe these changes as switching between low-dimensional embedding manifolds underlying a group of evolving agents.
Bollt, Erik M., Butail, Sachit, Gajamannage, Kelum, Porfiri, Maurizio   +3 more
core   +1 more source