Results 161 to 170 of about 3,979,422 (181)
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CRISPR in Animals and Animal Models
2017CRISPR-Cas9 has revolutionized the generation of transgenic animals. This system has demonstrated an unprecedented efficiency, multiplexability, and ease of use, thereby reducing the time and cost required for genome editing and enabling the production of animals with more extensive genetic modifications.
Ellen, Shrock, Marc, Güell
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Current animal models: cotton rat animal model.
Current topics in microbiology and immunology, 2009The cotton rat (Sigmodon hispidus) model has proven to be a suitable small animal model for measles virus pathogenesis to fill the niche between tissue culture and studies in macaques. Similar to mice, inbred cotton rats are available in a microbiologically defined quality with an ever-increasing arsenal of reagents and methods available for the study ...
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Animal Models of Osteoarthritis
Biorheology: The Official Journal of the International Society of Biorheology, 1999Animal models have proved to be of considerable importance in elucidating mechanisms underlying joint damage in osteoarthritis (OA) and providing proof of concept in the development of pharmacologic and biologic agents that may modify structural damage in the OA joint.
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Modeling Depression in Animal Models
2011Animal models and preclinical tests have played large roles in the development of antidepressant drugs and are likely to continue to play important roles. In the present communication, the main animal models of depression have been described and reviewed.
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