Results 21 to 30 of about 5,444,667 (291)

Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic islet

iScience, 2021
Summary: Pancreatic islets are essential for maintaining physiological blood glucose levels, and declining islet function is a hallmark of type 2 diabetes.
Belinda Yau, Sheyda Naghiloo, Alexis Diaz-Vegas, Austin V. Carr, Julian Van Gerwen, Elise J. Needham, Dillon Jevon, Sing-Young Chen, Kyle L. Hoehn, Amanda E. Brandon, Laurence Macia, Gregory J. Cooney, Michael R. Shortreed, Lloyd M. Smith, Mark P. Keller, Peter Thorn, Mark Larance, David E. James, Sean J. Humphrey, Melkam A. Kebede   +19 more
doaj   +1 more source

Effect of diazepam on kidney function and histological structure of white rat’s kidney

Journal of Biological Researches, 2016
The use of NAPZA (Narcotics, Alcohol, Psychotropic, and other addictive substances) in Indonesia keeps increasing. One type of frequently used NAPZAs is diazepam. Diazepam is a kind of sedative-hypnotics drug which belongs to benzodiazepine.
Putu Gede Martha Setiawan, Woro Anindito Sri Tunjung, Luthfi Nurhidayat   +2 more
doaj   +1 more source

Activity test of various mangosteen (Garcinia mangostana) pericarp extract fractions to decrease fasting blood cholesterol levels and lipid peroxidation activity in diabetic mice

Journal of Biological Researches, 2017
The objectives of this study were to determine the effect of various fractions of mangosteen (Garcinia mangostana) pericarp extract to the changes of the fasting blood cholesterol and serum malondialdehyde (MDA) levels on diabetic mice (Mus musculus ...
Saikhu Akhmad Husen, Dwi Winarni, Firas Khaleyla, Septian Hary Kalqutny   +3 more
doaj   +1 more source

Peptides for Skin Protection and Healing in Amphibians

Molecules, 2019
Amphibian skin is not to be considered a mere tegument; it has a multitude of functions related to respiration, osmoregulation, and thermoregulation, thus allowing the individuals to survive and thrive in the terrestrial environment.
Ilaria Demori, Zeinab El Rashed, Viola Corradino, Annamaria Catalano, Leila Rovegno, Linda Queirolo, Sebastiano Salvidio, Emanuele Biggi, Matteo Zanotti-Russo, Laura Canesi, Alessandro Catenazzi, Elena Grasselli   +11 more
doaj   +1 more source

The sinusoidal hematopoietic niche is formed by Jam1a via Notch signaling in the zebrafish kidney

iScience, 2023
Summary: The zebrafish is a unique model to understand hematopoietic niches as hematopoietic stem/progenitor cells are maintained in the kidney. However, little is known about which cell types in the kidney play a role in hematopoietic niches.
Mao Kondo, Koki Kimura, Jingjing Kobayashi-Sun, Shiori Yamamori, Makoto Taniguchi, David Traver, Isao Kobayashi   +6 more
doaj   +1 more source

C24:0 avoids cold exposure-induced oxidative stress and fatty acid β-oxidation damage

iScience, 2021
Summary: Low temperatures can cause severe growth inhibition and mortality in fish. Previous studies about the cold resistance of fish mainly focused on the role of unsaturated fatty acids, rather than saturated fatty acids (SFAs).
Shouxiang Sun, Xiaojuan Cao, Jian Gao
doaj   +1 more source

The effectiveness of animal physiology practical book based on guided inquiry model

JPBI (Jurnal Pendidikan Biologi Indonesia), 2019
The effectiveness of animal physiology practical book based on guided inquiry model is the essential factor to achievement student understanding a about animal physiology concepts.
Rina Widiana, Diana Susanti, Silvi Susanti, Ramadhan Sumarmin   +3 more
doaj   +1 more source

Celecoxib alleviates pathological cardiac hypertrophy and fibrosis via M1-like macrophage infiltration in neonatal mice

iScience, 2021
Summary: Cardiac hypertrophy is an adaptive response to all forms of heart disease, including hypertension, myocardial infarction, and cardiomyopathy. Cyclooxygenase-2 (COX-2) overexpression results in inflammatory response, cardiac cell apoptosis, and ...
Yanli Zhao, Qi Zheng, Hanchao Gao, Mengtao Cao, Huiyun Wang, Rong Chang, Changchun Zeng   +6 more
doaj   +1 more source

Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure

iScience, 2021
Summary: The kidneys balance many byproducts of the metabolism of dietary components. Previous studies examining dietary effects on kidney health are generally of short duration and manipulate a single macronutrient.
Amelia K. Fotheringham, Samantha M. Solon-Biet, Helle Bielefeldt-Ohmann, Domenica A. McCarthy, Aisling C. McMahon, Kari Ruohonen, Isaac Li, Mitchell A. Sullivan, Rani O. Whiddett, Danielle J. Borg, Victoria C. Cogger, William O. Ballard, Nigel Turner, Richard G. Melvin, David Raubenheimer, David G. Le Couteur, Stephen J. Simpson, Josephine M. Forbes   +17 more
doaj   +1 more source

Temperature increase and its effects on fish stress physiology in the context of global warming.

Journal of Fish Biology, 2020
The capacity of fishes to cope with environmental variation is considered to be a main determinant of their fitness and is partly determined by their stress physiology.
S. Alfonso, M. Gesto, B. Sadoul
semanticscholar   +1 more source