Results 81 to 90 of about 754,514 (306)
Journal of Animal Law, Ethics and One HealthThe 3R principles (Replacement, Reduction, Refinement) have become a widely used regulatory framework for governing animal research worldwide. While widely endorsed as a moral baseline, its actual capacity to protect animals and to support a transition ...
Rosa Maria Cajiga +5 more
doaj +1 more source
Recovery of “Intrinsic Value” Damages in Case of Negligently Killed Pet Dog [PDF]
, 2012 The North Carolina Court of Appeals, in a case where negligent killing of a pet dog with no market value was admitted, has denied recovery of “intrinsic” damages (also called “actual” damages). Shera v.
Gerber, Calley, Reppy, William A., Jr.
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
What is the Effect of Operational Managerial Practices on Dairy Farm Efficiency? Some Results from Sweden [PDF]
The article aims to investigate how operational managerial practices can contribute to improved farm level efficiency at dairy farms. Operational managerial practices are defined as animal health, breeding, and feeding practices. The main contribution of
Johansson, Helena, Ohlmer, Bo
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Development of a Strategic Approach for a Single EU Beef Market. Extensification. An Analysis of National and Competitive Issues [PDF]
, 2008 Working paperThe economic merits of the two Options for extensification under Agenda 2000 were evaluated in relation to their ability to generate revenue and their impact on the competitiveness of Irish cattle ...
Dunne, Liam +2 more
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Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
[Corrigendum] Establishment of hypoxia induction in an in vivo animal replacement model for experimental evaluation of pancreatic cancer. [PDF]
Oncol Rep, 2023 Bauer N +3 more
europepmc +1 more source
Evaluation of agro-industrial by-products as protein sources for duck production in the Mekong Delta of Vietnam [PDF]
, 2005 This thesis is based on four studies to determine the nutritive value and ileal and total tract amino acid digestibility of agro-industrial by-products, and the effects of inclusion of these by-products in diets on the biological performance of growing ...
Nguyen, Thi Kim Dong
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