Results 61 to 70 of about 321,984 (308)

Harmonising the definition of refinement [PDF]

, 2005
Russell and Burch's Three Rs (replacement, reduction and refinement) remain the cornerstone for principles guiding humane experimental research. However, the concept of refinement has evolved considerably since its first inception and there have been ...
Morton, David B, Vitale, Augusto, Pollo, Simone, Rennie, Anita, Buchanan-Smith, Hannah M, Prescott, Mark J   +5 more
core  

Fully adjusted systolic BP difference (mmHg) associated with replacement of 3 en% of carbohydrates or fat by total, plant or animal protein and by replacement of animal protein by plant protein. [PDF]

, 2013
Fully adjusted systolic BP difference (mmHg) associated with replacement of 3 en% of carbohydrates or fat by total, plant or animal protein and by replacement of animal protein by plant protein.
W. M. Monique Verschuren (304931), Wieke Altorf - van der Kuil (333558), Mariëlle F. Engberink (333561), Moniek M. Vedder (333564), Johanna M. Geleijnse (123731), Jolanda M. A. Boer (149282)   +5 more
core   +1 more source

Antioxidant Activity of Humulus lupulus Phenolic Hop Extracts in Creating a New Pâté: An Element Affecting Fat Stability and Microbiological Quality during Storage

Molecules
The aim of this study was to evaluate the effect of hop extracts on changes in the primary and secondary fat oxidation products, physicochemical properties, and microbiological quality of pâté-type offal sausages obtained through the partial replacement ...
Agnieszka Bilska, Joanna Kobus-Cisowska, Janusz Wojtczak, Ryszard Kowalski, Ewelina Kaczmarek   +4 more
doaj   +1 more source

The Sharing Experimental Animal Resources, Coordinating Holdings (SEARCH) Framework: Encouraging Reduction, Replacement, and Refinement in Animal Research.

PLoS Biology, 2017
While significant medical breakthroughs have been achieved through using animal models, our experience shows that often there is surplus material remaining that is frequently never revisited but could be put to good use by other scientists.
Bethny Morrissey, Karen Blyth, Phil Carter, Claude Chelala, Louise Jones, Ingunn Holen, Valerie Speirs   +6 more
doaj   +1 more source

Utilitarianism and Replaceability or Are Animals Expendable?

Between the Species: An Online Journal for the Study of Philosophy and Animals, 2011
In her very interesting paper, “Peter Singer on Expendability,” L. A. Kemmerer re-examines Peter Singer’s utilitarian argument implying that some being are replaceable and the implications of this argument for the issue of treating animals. I attempt to defend Singer, and more generally utilitarianism (including the principle of replaceability ...
openaire   +3 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

THE ESTIMATION OF CARCASS TRAITS OF BALI BULLS USING ULTRASOUND [PDF]

, 2010
A study was conducted to collect information on Bali bulls carcass traits estimation as one of the selection criteria using ultrasound. Ultrasonic estimation of carcass traits such as M. longissimus thoracis area (MLTA), Subcutaneous Fat Thickness (SFT)
Sri Rachma, AB, Harada, H
core  

How Can Systematic Reviews Teach Us More about the Implementation of the 3Rs and Animal Welfare? [PDF]

, 2019
Contains fulltext : 215451.pdf (Publisher’s version ) (Open Access)This paper describes the introduction of the systematic review methodology in animal-based research and the added value of this methodology in relation to the 3Rs and ...
Merel Ritskes-Hoitinga, Judith van Luijk, Ritskes-Hoitinga, M., Luijk, J. van   +3 more
core   +1 more source

From MilkingBots to RoboDolphins: How AI changes human-animal relations and enables alienation towards animals

Humanities & Social Sciences Communications
Technologies, especially disruptive technologies, have a great potential to change and reshape human-human as well as human-technology relations. This creates various ethical challenges that need to be addressed.
Leonie N. Bossert, Mark Coeckelbergh
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source