Results 81 to 90 of about 759,637 (306)

Recovery of “Intrinsic Value” Damages in Case of Negligently Killed Pet Dog [PDF]

, 2012
The North Carolina Court of Appeals, in a case where negligent killing of a pet dog with no market value was admitted, has denied recovery of “intrinsic” damages (also called “actual” damages). Shera v.
Gerber, Calley, Reppy, William A., Jr.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cross-Jurisdictional Study of the 3Rs: A Comparative Legal Analysis of Animal Research Governance in Finland and Switzerland

Journal of Animal Law, Ethics and One Health
The 3R principles (Replacement, Reduction, Refinement) have become a widely used regulatory framework for governing animal research worldwide. While widely endorsed as a moral baseline, its actual capacity to protect animals and to support a transition ...
Rosa Maria Cajiga, Charlotte Blattner, Birgitta Wahlberg, Markku Suksi, Fabrice Jotterand, Bernice Simone Elger   +5 more
doaj   +1 more source

What is the Effect of Operational Managerial Practices on Dairy Farm Efficiency? Some Results from Sweden [PDF]

The article aims to investigate how operational managerial practices can contribute to improved farm level efficiency at dairy farms. Operational managerial practices are defined as animal health, breeding, and feeding practices. The main contribution of
Johansson, Helena, Ohlmer, Bo
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Evaluation of agro-industrial by-products as protein sources for duck production in the Mekong Delta of Vietnam [PDF]

, 2005
This thesis is based on four studies to determine the nutritive value and ileal and total tract amino acid digestibility of agro-industrial by-products, and the effects of inclusion of these by-products in diets on the biological performance of growing ...
Nguyen, Thi Kim Dong
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Live Animal Ultrasound Information as a Decision Tool in Replacement Beef Heifer Programs [PDF]

Real-time ultrasound information taken on beef heifers prior to backgrounding is used to develop a logit model to aid heifer retention decisions. The value of ultrasound data is calculated as the difference in certainty equivalents between a decision ...
Anderson, John D., Dos Santos, Alecsandro, Vann, Rhonda C., Willard, Scott T.   +3 more
core   +1 more source

Ranking of Sire Breeds and Beef Cross Breeding of Dairy and Beef Cows [PDF]

, 2011
End of Project ReportSummary There is general agreement across countries on the ranking of beef breeds for production and carcass traits. Differences between dairy and early maturing beef breeds in growth and slaughter traits are small, but the latter ...
Keane, Michael G.
core