Results 71 to 80 of about 759,637 (306)

New stent for transapical mitral valve replacement in acute swine experiment

open access: yesJournal of Cardiothoracic Surgery, 2021
Background Many patients with mitral regurgitation are denied open-heart surgery due to perceived high risk. Transcatheter mitral valve replacement is a therapeutic alternative for patients at high surgical risk.
Yu Zou, Peng Teng, Liang Ma
doaj   +1 more source

Husbandry of Dairy Animals | Goat: Replacement Management

open access: yes, 2011
Raising replacement dairy kids begins with prenatal care of the doe. The doe needs to be properly vaccinated before kidding, be in proper body condition, and have good nutrition, including vitamins and minerals. A program to prevent caprine arthritis encephalitis must be instituted, which involves removal of the kid from the doe at birth, feeding heat ...
Hart, S., Delaney, C.
openaire   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Recent Developments in Animal Law [PDF]

open access: yes, 2005
This article focuses on recent developments in litigation and legislation involving the injury or death of animals. The article first discusses recent veterinary malpractice cases where the central issue was not related to damages.
Huss, Rebecca J.
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Development of MicroRNA Therapeutics for Hepatocellular Carcinoma

open access: yesDiagnostics, 2013
Hepatocellular carcinoma (HCC) is the most common form of liver cancer and is the third leading cause of cancer-related deaths worldwide. Treatment options for HCC are very limited, as it is often diagnosed at a late stage.
Rajagopal N. Aravalli
doaj   +1 more source

Recent advances in sturgeon nutrition. [PDF]

open access: yes, 2017
Sturgeons are fish species of biological and economical importance, and most of them are endangered, vulnerable or rare because of their large size, late sexual maturity, long period between spawning, and longevity.
Hung, Silas SO
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

What and why is the "evolutionary scale" in Swiss Animal Welfare Law? Putting the Platypus in its Place

open access: yesJournal of Animal Law, Ethics and One Health
In the Swiss Animal Welfare Law, paragraph 20 (2) specifically requires the selection of those animal species for experiments that are “lower on the evolutionary scale”.
Kirsten Persson   +5 more
doaj   +1 more source

NUTRITION AND THE ECONOMICS OF SWINE MANAGEMENT [PDF]

open access: yes
Current methods of formulating animal rations lead to excess nutrient excretion which can potentially lead to excess manure nutrients and an increase in economic costs. These methods do not recognize the impact of diminishing returns. The objective is to
Boland, Michael A.   +2 more
core   +1 more source

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