Results 51 to 60 of about 759,637 (306)

Infection Control Practices for Vascular Access Management in Hemodialysis: Results From a Nationwide Survey of Japanese National University Hospitals

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Bloodstream infections due to repeated vascular access (VA) puncture and circuit connections remain major concerns in hemodialysis. Therefore, we examined current practices for glove, disinfectant, and personal protective equipment (PPE) use according to VA type in national university hospitals in Japan.
Aiko Yamada, Makoto Harada, Tadahiko Kikugawa, Takeshi Nakata, Koji Hashimoto, Tsuneo Konta, Yuji Kamijo   +6 more
wiley   +1 more source

Practical implementation and impact of the 4R principles in ethnopharmacology: Pursuing a more humane approach to research

Frontiers in Pharmacology
Ethnopharmacology, a discipline focused on studying the medicinal use of natural materials by humans, plays a crucial role in addressing challenges in modern drug development.
Jimin Liu, Xiang Zai, Xiaqing Tian, Jiaxuan Li, Jiaxuan Li, Jiaxuan Li, Shipeng Yan, Taiyi Wang, Taiyi Wang, Taiyi Wang   +9 more
doaj   +1 more source

Replacement of Fish Meal by Defatted Yellow Mealworm (Tenebrio molitor) Larvae in Diet Improves Growth Performance and Disease Resistance in Red Seabream (Pargus major)

Animals, 2019
Yellow mealworm (Tenebrio molitor) larvae are a potential alternative animal protein source for sustainable aquaculture. However, reports on the successful complete substitution of fish meal with yellow mealworm larvae in an aquaculture diet have been ...
Atsushi Ido, Atsushi Hashizume, Takashi Ohta, Takayuki Takahashi, Chiemi Miura, Takeshi Miura   +5 more
doaj   +1 more source

Utilitarianism and Replaceability or Are Animals Expendable?

Between the Species: An Online Journal for the Study of Philosophy and Animals, 2011
In her very interesting paper, “Peter Singer on Expendability,” L. A. Kemmerer re-examines Peter Singer’s utilitarian argument implying that some being are replaceable and the implications of this argument for the issue of treating animals. I attempt to defend Singer, and more generally utilitarianism (including the principle of replaceability ...
openaire   +3 more sources

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Antioxidant Activity of Humulus lupulus Phenolic Hop Extracts in Creating a New Pâté: An Element Affecting Fat Stability and Microbiological Quality during Storage

Molecules
The aim of this study was to evaluate the effect of hop extracts on changes in the primary and secondary fat oxidation products, physicochemical properties, and microbiological quality of pâté-type offal sausages obtained through the partial replacement ...
Agnieszka Bilska, Joanna Kobus-Cisowska, Janusz Wojtczak, Ryszard Kowalski, Ewelina Kaczmarek   +4 more
doaj   +1 more source

The Sharing Experimental Animal Resources, Coordinating Holdings (SEARCH) Framework: Encouraging Reduction, Replacement, and Refinement in Animal Research.

PLoS Biology, 2017
While significant medical breakthroughs have been achieved through using animal models, our experience shows that often there is surplus material remaining that is frequently never revisited but could be put to good use by other scientists.
Bethny Morrissey, Karen Blyth, Phil Carter, Claude Chelala, Louise Jones, Ingunn Holen, Valerie Speirs   +6 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

In Search of a Sustainable Global Agri-Food System [PDF]

, 2013
The potential to meet global food demand fully exists through global development of the high-technology (HT), high-intensity type of agriculture and food processing system prevailing in developed countries.
Gooday, Andrew, Gooday, Andrew, KITAZATO, HIROSHI, NOMAKI, HIDETAKA, OGURI, KAZUMASA, TSUCHIYA, MASASHI, 北里, 洋, 土屋, 正史, 小栗, 一将, 野牧, 秀隆   +9 more
core   +2 more sources

Development of a protocol for maintaining viability while shipping organoid-derived retinal tissue. [PDF]

, 2020
Retinal organoid technology enables generation of an inexhaustible supply of three-dimensional retinal tissue from human pluripotent stem cells (hPSCs) for regenerative medicine applications.
Binette, Francois, Glickman, Randolph D, Nasonkin, Igor O, Petersen-Jones, Simon M, Seiler, Magdalene, Singh, Ratnesh K, Winkler, Paige   +6 more
core   +1 more source