Results 31 to 40 of about 759,637 (306)

Comparative grazing behaviour of lactating suckler cows of contrasting genetic merit and genotype [PDF]

, 2018
peer-reviewedThe objective of this study was to determine if differences in grazing behaviour exist between lactating suckler cows diverse in genetic merit for the national Irish Replacement index and of two contrasting genotypes.
McCabe, S., McHugh, Noirin, O'Connell, Niamh E., Prendiville, Robert   +3 more
core   +1 more source

Microfluidics : the fur-free way towards personalised medicine in cancer therapy [PDF]

, 2016
Microfluidic technology has great potential for complementing and, in some instances, replacing the use of animal models in the testing of medicines and in developing personalised treatments for cancer patients.
Bower, Ruth, Dawson, Amy, Green, Vicky, Greenman, John   +3 more
core  

Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan, Lydie Da Costa, Ludivine David Nguyen, Heloise Chosseler, Audrey Riquet, Benedicte Bruno, Melissa Barbati   +6 more
wiley   +1 more source

Human cardiomyocytes for drug discovery

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2018
Introduction: Cardiac drug discovery are based in old methods that use animals, animal cells or modified cells that do not faithfully represent human cardiac phenotypes.
Diogo Gonçalves Biagi, Jéssica Gonçalves, Estela Cruvinel, Renata Damiani, Flavia Valgode, Fabiana Medeiros, Camila G Moreira, Evelyn Santos, Rodrigo Marcon, Calixto João, Gabriela Venturini, Alexandre Pereira, Éden Ferreira, Renato Mortara, Marcos C Valadares   +14 more
doaj   +7 more sources

Alternative in vitro and in silico models to reduce animal use: a crucial technological advance in dermatological sciences

Expert Reviews in Molecular Medicine
Introduction Alternative models are tools to replace and reduce the number of animals used in biomedical sciences, for either research or tests of industrial products. Several new alternative models have been developed in the most diverse fields.
Carla Zanatelli, Luiza Pretto, Thaís Casagrande Paim, Márcia Rosângela Wink   +3 more
doaj   +1 more source

Non-animal-based options for animal-based foods- towards a systematic terminology

Frontiers in Nutrition, 2023
The market has seen a rapid increase in animal-free products intended to replace animal-based foods due to concerns for human health and environmental sustainability.
Nazanin Abbaspour, Ruben Sanchez-Sabate, Ruben Sanchez-Sabate, Joan Sabaté   +3 more
doaj   +1 more source

Towards animal oriented rearing methods in organic production systems [PDF]

, 2006
One of the foundations of organic animal production systems is that animals are kept in a more natural way. In terms of housing, animals get more space, have access to outside areas and are fed organic rations.

core  

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee, Holly Evans, Claire E. Wakefield, Antoinette Anazodo, Richard J. Cohn, Brittany C. McGill, Elizabeth A. Lobb, Lori Wiener, Madeleine L. Juhrmann, Ursula M. Sansom‐Daly   +9 more
wiley   +1 more source

Suckling as an alternative rearing system for replacement calves on dairy farms [PDF]

, 2004
The aim is to develop an alternative calf rearing system for replacement calves that will improve animal welfare on dairy farms and meets the requirements of farmers in terms of practicality and cost. On the dairy farms that make use of a suckling system
Langhout, Jos, Wagenaar, Jan-Paul
core  

Replacing animals in biomedical research [PDF]

Nature, 1978
Alternatives to Animal Experiments. By D. H. Smyth. Pp. 216. (Scolar Press: London, 1978.) Hardback £6; paperback £2.90.
openaire   +1 more source