Results 31 to 40 of about 311,505 (261)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas +7 more
wiley +1 more source
Human cardiomyocytes for drug discovery
Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2018 Introduction: Cardiac drug discovery are based in old methods that use animals, animal cells or modified cells that do not faithfully represent human cardiac phenotypes.
Diogo Gonçalves Biagi +14 more
doaj +7 more sources
Replacing animals in biomedical research [PDF]
Nature, 1978 Alternatives to Animal Experiments. By D. H. Smyth. Pp. 216. (Scolar Press: London, 1978.) Hardback £6; paperback £2.90.
openaire +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Person‐centred follow‐up care based on evidence‐based clinical practice guidelines and providing individualised information should help to inform and reassure survivors about their medical and psychosocial situation and provide treatment and support where needed.
Gisela Michel +36 more
wiley +1 more source
Applied Sciences, 2021 Fishmeal is the main source of dietary protein for most commercially farmed fish species. However, fishmeal prices have been raised even further because of competition with domestic animals, shortage in world fishmeal supply, and increased demand ...
Rendani Luthada-Raswiswi +2 more
doaj +1 more source
Husbandry of Dairy Animals | Goat: Replacement Management
, 2011 Raising replacement dairy kids begins with prenatal care of the doe. The doe needs to be properly vaccinated before kidding, be in proper body condition, and have good nutrition, including vitamins and minerals. A program to prevent caprine arthritis encephalitis must be instituted, which involves removal of the kid from the doe at birth, feeding heat ...
Hart, S., Delaney, C.
openaire +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases impact prognosis. 18F‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) and bone marrow aspirate and trephine biopsies (BMAT) are used to identify disease involvement.
Imogen Andrews +3 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan +3 more
wiley +1 more source
The ‘R’ principles in laboratory animal experiments
Laboratory Animal Research, 2020 Since the Three Rs of replacement, reduction and refinement was proposed by Russel and Birch in 1959, researchers have a moral duty to minimize harm to animals. Even though animal experiments are performed by the Three Rs concept, animal researches which
Kook Hyun Lee +2 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source