Results 201 to 210 of about 5,358,841 (304)
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Advances in single-cell transcriptomics in animal research. [PDF]
J Anim Sci BiotechnolYan Y +8 more
europepmc +1 more source
Assessing the impact of better control of livestock diseases in Africa [PDF]
, 2012 International Laboratory for Research on Animal Diseases
core
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Contributing to evidence-based veterinary medicine: A qualitative study of veterinary professionals' views and experiences of client-owned companion animal research. [PDF]
PLoS OneFurtado T, Perkins E, Archer DC.
europepmc +1 more source
The carrier state in cattle infected with Theileria parva [PDF]
, 2012 International Laboratory for Research on Animal Diseases
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Challenges and opportunities of translating animal research into human trials in Ethiopia. [PDF]
BMC Med Res MethodolAbrhaley A, Giday M, Hailu A.
europepmc +1 more source
Geographic Information Systems [PDF]
, 2012 International Laboratory for Research on Animal Diseases
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source