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Animal Testing Alternatives: Online Resources

open access: yesIssues in Science and Technology Librarianship, 2000
This article focuses on bibliographic databases and web sites that provide information on the scientific aspects of animal testing alternatives and not on the pros and cons of animal rights.
Elizabeth Choinski
doaj   +2 more sources

Antibody-based alternatives to animal testing for toxin detection and antitoxin evaluation [PDF]

open access: yesFrontiers in Toxicology
Animal experiments have long played a central role in biomedical research and toxicology, yet their limitations in translational accuracy and ethical concerns have intensified the demand for reliable alternatives.
Seo-Hyuk Chang   +17 more
doaj   +2 more sources

AI: the Apollo guidance computer of the Exposome moonshot [PDF]

open access: yesFrontiers in Artificial Intelligence
The Exposome—the totality of environmental exposures across a lifetime—remains one of the most significant challenges in understanding and preventing human disease.
Fenna C. M. Sillé   +3 more
doaj   +2 more sources

Alternatives to Animal Testing [PDF]

open access: yesJournal of Toxicology: Cutaneous and Ocular Toxicology, 1994
(1996). Alternatives to Animal Testing. Journal of Toxicology: Cutaneous and Ocular Toxicology: Vol. 15, No. 1, pp. 29-31.
  +6 more sources

Eliminate the In Vivo Digestibility Requirement for Protein Content Claims in North America to Align Consumer Purchasing Behavior with Dietary Guidelines [PDF]

open access: yesCurrent Developments in Nutrition
A roundtable discussion, held on 10 December, 2024, addressed requirements for protein quality assessment in United States and Canadian food labeling regulations, focusing on concerns with the protein digestibility-corrected amino acid score (PDCAAS ...
Joseph Manuppello   +6 more
doaj   +2 more sources

Using in silico tools to predict flame retardant metabolites for more informative exposomics-based approaches

open access: yesFrontiers in Toxicology, 2023
Introduction: The positive identification of xenobiotics and their metabolites in human biosamples is an integral aspect of exposomics research, yet challenges in compound annotation and identification continue to limit the feasibility of comprehensive ...
Breanne Kincaid   +6 more
doaj   +1 more source

Similarities and Differences in Gene Expression Networks Between the Breast Cancer Cell Line Michigan Cancer Foundation-7 and Invasive Human Breast Cancer Tissues

open access: yesFrontiers in Artificial Intelligence, 2021
Failure to adequately characterize cell lines, and understand the differences between in vitro and in vivo biology, can have serious consequences on the translatability of in vitro scientific studies to human clinical trials.
Vy Tran   +6 more
doaj   +1 more source

Oligodendrogenesis and myelination tracing in a CRISPR/Cas9-engineered brain microphysiological system

open access: yesFrontiers in Cellular Neuroscience, 2023
IntroductionOligodendrocytes (OLs) are the myelin-forming cells of the central nervous system (CNS). Although OLs can be differentiated from human-induced pluripotent stem cells (hiPSCs), the in vitro modeling of axon myelination in human cells remains ...
July Carolina Romero   +6 more
doaj   +1 more source

Artificial intelligence as the new frontier in chemical risk assessment

open access: yesFrontiers in Artificial Intelligence, 2023
The rapid progress of AI impacts various areas of life, including toxicology, and promises a major role for AI in future risk assessments. Toxicology has shifted from a purely empirical science focused on observing chemical exposure outcomes to a data ...
Thomas Hartung, Thomas Hartung
doaj   +1 more source

Deconvoluting gene and environment interactions to develop an “epigenetic score meter” of disease

open access: yesEMBO Molecular Medicine, 2023
Human health is determined both by genetics (G) and environment (E). This is clearly illustrated in groups of individuals who are exposed to the same environmental factor showing differential responses.
Alessio Butera   +6 more
doaj   +1 more source

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