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Animal Testing Alternatives: Online Resources
This article focuses on bibliographic databases and web sites that provide information on the scientific aspects of animal testing alternatives and not on the pros and cons of animal rights.
Elizabeth Choinski
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Antibody-based alternatives to animal testing for toxin detection and antitoxin evaluation [PDF]
Animal experiments have long played a central role in biomedical research and toxicology, yet their limitations in translational accuracy and ethical concerns have intensified the demand for reliable alternatives.
Seo-Hyuk Chang +17 more
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AI: the Apollo guidance computer of the Exposome moonshot [PDF]
The Exposome—the totality of environmental exposures across a lifetime—remains one of the most significant challenges in understanding and preventing human disease.
Fenna C. M. Sillé +3 more
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Alternatives to Animal Testing [PDF]
(1996). Alternatives to Animal Testing. Journal of Toxicology: Cutaneous and Ocular Toxicology: Vol. 15, No. 1, pp. 29-31.
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Eliminate the In Vivo Digestibility Requirement for Protein Content Claims in North America to Align Consumer Purchasing Behavior with Dietary Guidelines [PDF]
A roundtable discussion, held on 10 December, 2024, addressed requirements for protein quality assessment in United States and Canadian food labeling regulations, focusing on concerns with the protein digestibility-corrected amino acid score (PDCAAS ...
Joseph Manuppello +6 more
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Introduction: The positive identification of xenobiotics and their metabolites in human biosamples is an integral aspect of exposomics research, yet challenges in compound annotation and identification continue to limit the feasibility of comprehensive ...
Breanne Kincaid +6 more
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Failure to adequately characterize cell lines, and understand the differences between in vitro and in vivo biology, can have serious consequences on the translatability of in vitro scientific studies to human clinical trials.
Vy Tran +6 more
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IntroductionOligodendrocytes (OLs) are the myelin-forming cells of the central nervous system (CNS). Although OLs can be differentiated from human-induced pluripotent stem cells (hiPSCs), the in vitro modeling of axon myelination in human cells remains ...
July Carolina Romero +6 more
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Artificial intelligence as the new frontier in chemical risk assessment
The rapid progress of AI impacts various areas of life, including toxicology, and promises a major role for AI in future risk assessments. Toxicology has shifted from a purely empirical science focused on observing chemical exposure outcomes to a data ...
Thomas Hartung, Thomas Hartung
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Deconvoluting gene and environment interactions to develop an “epigenetic score meter” of disease
Human health is determined both by genetics (G) and environment (E). This is clearly illustrated in groups of individuals who are exposed to the same environmental factor showing differential responses.
Alessio Butera +6 more
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