Results 31 to 40 of about 281,616 (305)

Effect of sub-chronic exposure to cigarette smoke, electronic cigarette and waterpipe on human lung epithelial barrier function

BMC Pulmonary Medicine, 2020
Background Taking into consideration a recent surge of a lung injury condition associated with electronic cigarette use, we devised an in vitro model of sub-chronic exposure of human bronchial epithelial cells (HBECs) in air-liquid interface, to ...
Baishakhi Ghosh, Hermes Reyes-Caballero, Sevcan Gül Akgün-Ölmez, Kristine Nishida, Lakshmana Chandrala, Lena Smirnova, Shyam Biswal, Venkataramana K. Sidhaye   +7 more
doaj   +1 more source

Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory

Communications Biology
Brain Microphysiological Systems, including neural organoids derived from human induced pluripotent stem cells, offer a unique lens to study the intricate workings of the human brain.
Dowlette-Mary Alam El Din, Leah Moenkemoeller, Alon Loeffler, Forough Habibollahi, Jack Schenkman, Amitav Mitra, Tjitse van der Molen, Lixuan Ding, Jason Laird, Maren Schenke, Erik C. Johnson, Brett J. Kagan, Thomas Hartung, Lena Smirnova   +13 more
doaj   +1 more source

First Organoid Intelligence (OI) workshop to form an OI community

Frontiers in Artificial Intelligence, 2023
The brain is arguably the most powerful computation system known. It is extremely efficient in processing large amounts of information and can discern signals from noise, adapt, and filter faulty information all while running on only 20 watts of power ...
Itzy E. Morales Pantoja, Lena Smirnova, Alysson R. Muotri, Alysson R. Muotri, Karl J. Wahlin, Jeffrey Kahn, J. Lomax Boyd, David H. Gracias, David H. Gracias, David H. Gracias, David H. Gracias, David H. Gracias, David H. Gracias, Timothy D. Harris, Timothy D. Harris, Tzahi Cohen-Karni, Tzahi Cohen-Karni, Brian S. Caffo, Alexander S. Szalay, Alexander S. Szalay, Alexander S. Szalay, Fang Han, Donald J. Zack, Donald J. Zack, Donald J. Zack, Donald J. Zack, Ralph Etienne-Cummings, Akwasi Akwaboah, July Carolina Romero, Dowlette-Mary Alam El Din, Jesse D. Plotkin, Barton L. Paulhamus, Erik C. Johnson, Frederic Gilbert, J. Lowry Curley, Ben Cappiello, Jens C. Schwamborn, Eric J. Hill, Paul Roach, Daniel Tornero, Daniel Tornero, Caroline Krall, Caroline Krall, Rheinallt Parri, Fenna Sillé, Andre Levchenko, Rabih E. Jabbour, Brett J. Kagan, Cynthia A. Berlinicke, Qi Huang, Alexandra Maertens, Kathrin Herrmann, Katya Tsaioun, Raha Dastgheyb, Christa Whelan Habela, Joshua T. Vogelstein, Thomas Hartung, Thomas Hartung   +57 more
doaj   +1 more source

Progress Toward Replacing Animals in Toxicity Testing for Cosmetics [PDF]

, 2012
In the 1980’s, animal rights activists successfully motivated the cosmetic industry to begin researching alternatives to animal tests.
Nye, Marisa B.
core  

EURL ECVAM Strategy to replace, reduce and refine the use of fish in aquatic toxicity and bioaccumulation testing [PDF]

, 2014
The assessment of aquatic toxicity and bioaccumulation are important components of the environmental hazard and risk assessment of all types of chemicals, and are therefore included in several pieces of European Union and international legislation.
HALDER MARIA ELISABETH, KIENZLER AUDE, WHELAN Maurice, WORTH Andrew   +3 more
core   +1 more source

Exploring Preferences for a Digital Single‐Session Intervention for Adolescent Siblings of Youth With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Adolescent siblings of children with cancer are at elevated risk for psychosocial problems. Unfortunately, various barriers such as limited family time and resources, conflicting schedules, and psychosocial staffing constraints at cancer centers hinder sibling access to support.
Christina M. Amaro, Sarah Silver, Prishi Patel, Meredith K. Reffner Collins, Kimberly S. Canter, Stephanie Fooks‐Parker, Michael Amylon, Shawna V. Hudson, Jessica L. Schleider, Melissa A. Alderfer, Katie A. Devine   +10 more
wiley   +1 more source

Microglia-containing neural organoids as brain microphysiological systems for long-term culture

Frontiers in Cellular Neuroscience
Microglia, essential for brain development, homeostasis, and neuroinflammation, originate from the yolk sac during embryogenesis and migrate into the developing brain.
Alex Rittenhouse, Caroline Krall, Caroline Krall, Jesse Plotkin, Dowlette-Mary Alam El Din, Breanne Kincaid, Jason Laird, Lena Smirnova   +7 more
doaj   +1 more source

Guidance on assessing the methodological and reporting quality of toxicologically relevant studies: A scoping review

Environment International, 2016
Assessments of methodological and reporting quality are critical to adequately judging the credibility of a study's conclusions and to gauging its potential reproducibility.
Gbeminiyi O. Samuel, Sebastian Hoffmann, Robert A. Wright, Manoj Mathew Lalu, Grace Patlewicz, Richard A. Becker, George L. DeGeorge, Dean Fergusson, Thomas Hartung, R. Jeffrey Lewis, Martin L. Stephens   +10 more
doaj   +1 more source

Testing, Testing 1,2,3 [PDF]

, 2012
Overview: Since childhood, most human beings have been raised on the foundation of accepting and adhering to the “Golden Rule” in everyday aspects of life.
Hogenkamp, Eugenia
core   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source