Results 51 to 60 of about 57,035 (299)
Animal Rights Coalitions Coordinator\u27s Report \u2786 [PDF]
, 1987 New strategies fuel progress, promise even greater gains Milestones On a personal note Here\u27s what you can do to make a difference Promoting animal rights at the community level (Ann T.
Animal Rights Coalitions
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Alternatives to Animal Testing and the 2020 Lush Awards [PDF]
, 2020 The cosmetics company Lush recently announced its 2020 Lush Prizes. The program bestows awards on scientists and animal advocates for advancing the science and also the cause of alternatives to the use of animals in chemical safety testing.
Rowan, Kathleen
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A novel human organotypic tumor invasion model of cell line MDA-MB-231 in Precision-Cut Lung Slices (PCLS) to reduce animal experiments in preclinical oncology [PDF]
, 2022 S.134Cancer such as breast carcinoma is a major public health problem worldwide. The actual cause of death is the formation of metastasis which often occurs in the lung.
Konzok, Sebastian +5 more
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Alternatives to Animal Experimentation [PDF]
, 1983 Alternatives to animal experimentation are highly touted today by animal welfare advocates. Their campaign for adoption of alternatives has caused much discussion and debate within and outside of the biomedical community. The purpose of this paper was to
Niemi, Steven M.
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Green toxicology only becomes beautiful through AI
Frontiers in ChemistryGreen Toxicology extends the principles of Green Chemistry by embedding toxicological foresight into chemical design, with the aim of preventing hazards before substances reach markets or the environment.
Alexandra Maertens +3 more
doaj +1 more source
Advanced Science, 2022 With the definition of the 3R principle by Russel and Burch in 1959, the search for an adequate substitute for animal testing has become one of the most important tasks and challenges of this time, not only from an ethical, but also from a scientific ...
Elena Stengelin +2 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Prevalidation study for testing the toxic effects of inhalable substances (gases) on human lung cells using an air/liquid culture technique [PDF]
, 2008 To date, studies of inhalation toxicity of air contaminants are restricted to animal experiments, mainly because of difficulties in exposing cell cultures directly to these substances. The increasing demand for assessing inhalation toxicity hazards calls
Otto,C. +12 more
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