Results 41 to 50 of about 923,548 (275)
Bottom-up physiologically-based biokinetic modelling as an alternative to animal testing
ALTEX, 2019 There is a growing need for alternatives to animal testing to derive biokinetic data for evaluating both efficacy and safety of chemicals. One such alternative is bottom-up physiologically-based biokinetic (PBK) modeling which requires only in vitro data.
James Chan
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Animal testing and its alternatives - the most important omics is economics.
ALTEX, 2018 For a long time, the discussion about animal testing vs its alternatives centered on animal welfare. This was a static warfare, or at least a gridlock, where life scientists had to take a position and make their value choices and hardly anyone changed ...
L. Meigs +4 more
semanticscholar +1 more source
Predicting toxicity of chemicals: software beats animal testing
EFSA Journal, 2019 We created earlier a large machine‐readable database of 10,000 chemicals and 800,000 associated studies by natural language processing of the public parts of Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) registrations until
Thomas Hartung
doaj +1 more source
BMC Pulmonary Medicine, 2020 Background Taking into consideration a recent surge of a lung injury condition associated with electronic cigarette use, we devised an in vitro model of sub-chronic exposure of human bronchial epithelial cells (HBECs) in air-liquid interface, to ...
Baishakhi Ghosh +7 more
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First Organoid Intelligence (OI) workshop to form an OI community
Frontiers in Artificial Intelligence, 2023 The brain is arguably the most powerful computation system known. It is extremely efficient in processing large amounts of information and can discern signals from noise, adapt, and filter faulty information all while running on only 20 watts of power ...
Itzy E. Morales Pantoja +57 more
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Alternatives to Animal Use in Research, Testing, and Education [PDF]
Journal of Neuropathology & Experimental Neurology, 1989 Peter Safar, Ann Radovsky
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QSAR Models for the Prediction of Dietary Biomagnification Factor in Fish
Toxics, 2023 Xenobiotics released in the environment can be taken up by aquatic and terrestrial organisms and can accumulate at higher concentrations through the trophic chain.
Linda Bertato +2 more
doaj +1 more source
Predicting the Bioconcentration Factor in Fish from Molecular Structures
Toxics, 2022 The bioconcentration factor (BCF) is one of the metrics used to evaluate the potential of a substance to bioaccumulate into aquatic organisms. In this work, linear and non-linear regression QSARs were developed for the prediction of log BCF using ...
Linda Bertato +2 more
doaj +1 more source
Alternatives to animal experimentation [PDF]
BMJ, 2007 After two decades of decline, the use of animals in research is beginning to rise again. Geoff Watts examines replacement techniques and the potential for eliminating the need to use living ...
openaire +3 more sources
Brain organoids and organoid intelligence from ethical, legal, and social points of view
Frontiers in Artificial IntelligenceHuman brain organoids, aka cerebral organoids or earlier “mini-brains”, are 3D cellular models that recapitulate aspects of the developing human brain.
Thomas Hartung +3 more
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