Results 91 to 100 of about 747,053 (355)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

The diversity of livestock systems and definition of animal welfare (2nd NAHWOA Workshop) [PDF]

open access: yes, 2000
content: Part A: Livestock in organic farming: role and research methodologies Part B: The diversity of organic livestock systems – Austria and Spain Part C: Organic livestock production standards Part D: Organic livestock production and animal ...

core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Health and welfare of organic livestock [PDF]

open access: yes, 2009
Animal health and welfare are important principles of organic animal husbandry. In the Netherlands organic animal husbandry has proven to perform better than the conventional sector on many aspects of animal welfare.
Hommes, M., Sukkel, W.
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Scientific Opinion on the use of animal‐based measures to assess welfare in pigs

open access: yesEFSA Journal, 2012
Animal‐based measures, identified on the basis of scientific evidence, can be used effectively in the evaluation of the welfare of on‐farm pigs in relation to laws, codes of practice, quality assurance schemes and management.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

Utilitarianism and animal cruelty: Further doubts [PDF]

open access: yes, 2016
Utilitarianism has an apparent pedigree when it comes to animal welfare. It supports the view that animal welfare matters just as much as human welfare. And many utilitarians support and oppose various practices in line with more mainstream concern over ...
Davies, Ben
core   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

African swine fever

open access: yesEFSA Journal, 2015
Since entering the eastern EU at the start of 2014, African swine fever (ASF) has spread locally in the wild boar population, independently of outbreaks in domestic pigs.
EFSA Panel on Animal Health and Welfare (AHAW)
doaj   +1 more source

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