Results 61 to 70 of about 164,824 (310)

Thiosquaramides: pH switchable anion transporters [PDF]

, 2014
The transport of anions across cellular membranes is an important biological function governed by specialised proteins. In recent years, many small molecules have emerged that mimick the anion transport behaviour of these proteins, but only a few of ...
Busschaert, Nathalie, Chan, Bun, Czech, Dawid D., Elmes, Robert B. P., Gale, Philip A., Hendzel, Kevin D., Jolliffe, Katrina A., Kirby, Isabelle L., Peck, Evan M., Shaw, Scott K., Smith, Bradley D., Wu, Xin   +11 more
core   +1 more source

Rat Erythrocytes Express the Anionic Amino Acid Transport Protein EAAC1

Blood Cells, Molecules, and Diseases, 2002
EAAC1 is a widely expressed protein which transports anionic amino acids in a Na(+)-dependent fashion. Rat erythrocytes have generally been thought to be impermeant to anionic amino acids. Utilizing immunoelectron microscopy, we have demonstrated the presence of EAAC1-immunoreactive protein within rat erythrocytes.
Department of Pediatrics, University of Florida College of Medicine, Gainesville, Florida ( host institution ), Novak, Donald, Beveridge, Mark, Verlander-Reed, Jill   +3 more
openaire   +3 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Physiology and pathophysiology of ClC-K/barttin channels

Frontiers in Physiology, 2010
ClC-K channels form a subgroup of anion channels within the ClC family of anion transport proteins. They are expressed predominantly in the kidney and in the inner ear, and are necessary for NaCl resorption in the loop of Henle and for K+ secretion by ...
Christoph eFahlke, Martin eFischer
doaj   +1 more source

N-Glycosylation dictates proper processing of organic anion transporting polypeptide 1B1. [PDF]

PLoS ONE, 2012
Organic anion transporting polypeptides (OATPs) have been extensively recognized as key determinants of absorption, distribution, metabolism and excretion (ADME) of various drugs, xenobiotics and toxins.
Juan Yao, Weifang Hong, Jiujiu Huang, Kai Zhan, Hong Huang, Mei Hong   +5 more
doaj   +1 more source

TSPO: kaleidoscopic 18-kDa amid biochemical pharmacology, control and targeting of mitochondria [PDF]

, 2016
The 18-kDa translocator protein (TSPO) localizes in the outer mitochondrial membrane (OMM) of cells and is readily up-regulated under various pathological conditions such as cancer, inflammation, mechanical lesions and neurological diseases. Able to bind
Aghazadeh, Aghazadeh, Alho, Amitani, Anholt, Anholt, Anholt, Anholt, Antkiewicz-Michaluk, Arbo, Banati, Banati, Bar-Ami, Barron, Basile, Batarseh, Batarseh, Batarseh, Batarseh, Batra, Beinlich, Benavides, Bernassau, Besman, Bird, Bitran, Bose, Boujrad, Boujrad, Braestrup, Bribes, Bribes, Brunette, Cagnin, Campanella, Campioli, Casellas, Chauveau, Chen, Chen, Cho, Clark, Colasanti, Corcia, Costa, Costa, Costa, Cuhlmann, Daugherty, De Souza, Decaudin, Decker, Delavoie, Delerive, Doperalski, Enders, Epstein, Fafalios, Fan, Fan, Fan, Fur, Fur, Galiegue, Gastaldello, Gatliff, Gatliff, Gavish, Gavish, Gazouli, Gehlert, Gerhard, Gervois, Giatti, Giatzakis, Giatzakis, Golani, Gonzalez-Polo, Guillon, Gulyas, Guo, Guo, Gut, Hardwick, Hardwick, Hauet, Hauet, Jamin, Jaremko, Jaremko, Jemma Gatliff, Joo, Joseph-Liauzun, Karlstetter, Kita, Kondo, Konigsrainer, Korkhov, Kreisl, Kruczek, Kumar, Lacapere, Lacapere, Lavisse, Li, Li, Li, Li, Li, Li, Libby, Liu, Liu, Maia, Maury, Mazurika, McEnery, Miao, Michelangelo Campanella, Midzak, Midzak, Miettinen, Miller, Mills, Mizrahi, Morohaku, Murail, Nagler, Obame, Oberto, Olson, Ostuni, Ouchi, Owen, Owen, Owen, Papadopoulos, Papadopoulos, Papadopoulos, Papadopoulos, Papadopoulos, Papadopoulos, Papadopoulos, Paradis, Pastorino, Pelechano, Petrescu, Poynter, Raghavan, Rey, Romeo, Rone, Rosenberg, Rosenberg, Rosenberg, Rupprecht, Rupprecht, Scarf, Schaller, Selvaraj, Shoukrun, Sileikyte, Soustiel, Sutter, Tang, Taylor, Teboul, Thompson, Trincavelli, Tu, Tu, Tu, Vanhee, Varrone, Vega, Verma, Wang, Wang, Wei, Whalin, Xiao, Yang, Yang, Yasuno, Yeliseev, Yoder, Zhang, Zhang, Zhao, Zhou   +189 more
core   +1 more source

Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1997
We studied the ATP-dependent uptake of dinitrophenyl-glutathione (GS-DNP) into plasma membrane vesicles derived from parental GLC4 cells and from multidrug resistant GLC4/ADR cells. The latter have a high expression of the multidrug resistance protein (MRP).
Heijn, M., Hooijberg, J.H., Scheffer, G.L., Szabó, G., Westerhoff, H.V., Lankelma, J.   +5 more
openaire   +2 more sources

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

FEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq, Nestor G. Casillas‐Vega, Alma Gomez‐Loredo, Xristo Zarate   +3 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Level of membrane-bound hemoglobin and red-cell membrane proteins in patients with essential hypertension complicated and not complicated with metabolic syndrome

Acta Biomedica Scientifica, 2016
We studied the effect of different levels of membrane-bound hemoglobin on the level of red-cell membrane proteins and also their interrelation in patients with essential hypertension with and without metabolic syndrome.
Y. I. Pivovarov, E. E. Kuznetsova, V. G. Gorokhova, A. S. Sergeyeva, I. V. Babushkina, L. B. Koryakina, E. O. Andreyeva   +6 more
doaj   +1 more source