Results 61 to 70 of about 373,177 (393)

The minimal structure containing the band 3 anion transport site. A 35Cl NMR study [PDF]

, 1985
35Cl NMR, which enables observation of chloride binding to the anion transport site on band 3, is used in the present study to determine the minimal structure containing the intact transport site.
Chan, Sunney I., Falke, Joseph J., Kanes, Katherine J.   +2 more
core  

Highly effective yet simple transmembrane anion transporters based upon ortho-phenylenediamine bis-ureas

, 2014
Simple, highly fluorinated receptors are shown to function as highly effective transmembrane anion antiporters with the most active transporters rivalling the transport efficacy of natural anion transporter prodigiosin for ...
Gale, Philip A., Haynes, Cally J. E., Holder, Katie J., Karagiannidis, Louise E., Kirby, Isabelle L., Moore, Stephen J., Wells, Neil J.   +6 more
core   +1 more source

H+ transport is an integral function of the mitochondrial ADP/ATP carrier. [PDF]

, 2019
The mitochondrial ADP/ATP carrier (AAC) is a major transport protein of the inner mitochondrial membrane. It exchanges mitochondrial ATP for cytosolic ADP and controls cellular production of ATP.
Angelin, Alessia, Bertholet, Ambre M, Cho, Joonseok, Chouchani, Edward T, Fedorenko, Andriy, Garrity, Ryan, Kazak, Lawrence, Kirichok, Yuriy, Long, Jonathan Z, Spiegelman, Bruce M, Terada, Naohiro, Vidoni, Sara, Wallace, Douglas C   +12 more
core   +1 more source

GABA signalling modulates plant growth by directly regulating the activity of plant-specific anion transporters

Nature Communications, 2015
The non-protein amino acid, gamma-aminobutyric acid (GABA) rapidly accumulates in plant tissues in response to biotic and abiotic stress, and regulates plant growth.
Sunita A. Ramesh, S. Tyerman, Bo Xu, J. Bose, S. Kaur, Vanessa M. Conn, P. Domingos, S. Ullah, Stefanie Wege, S. Shabala, J. Feijó, P. Ryan, Matthew Gilliham   +12 more
semanticscholar   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source

Genome-wide identification and in silico analysis of NPF, NRT2, CLC and SLAC1/SLAH nitrate transporters in hexaploid wheat (Triticum aestivum)

Scientific Reports, 2022
Nitrogen transport is one of the most important processes in plants mediated by specialized transmembrane proteins. Plants have two main systems for nitrogen uptake from soil and its transport within the system—a low-affinity transport system and a high ...
Aman Kumar, Nitika Sandhu, Pankaj Kumar, Gomsie Pruthi, Jasneet Singh, Satinder Kaur, Parveen Chhuneja   +6 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Absolute Protein Amounts and Relative Abundance of Volume-regulated Anion Channel (VRAC) LRRC8 Subunits in Cells and Tissues Revealed by Quantitative Immunoblotting [PDF]

, 2019
The volume-regulated anion channel (VRAC) plays an important role in osmotic cell volume regulation. In addition, it is involved in various physiological processes such as insulin secretion, glia-neuron communication and purinergic signaling.
Kopp, Anja, Pervaiz, Sumaira, Stauber, Tobias, von Kleist, Lisa   +3 more
core   +1 more source

Regorafenib Is Transported by the Organic Anion Transporter 1B1 and the Multidrug Resistance Protein 2

Biological & Pharmaceutical Bulletin, 2015
Regorafenib is a small molecule inhibitor of tyrosine kinases, and has been shown to improve the outcomes of patients with advanced colorectal cancer and advanced gastrointestinal stromal tumors. The transport profiles of regorafenib by various transporters were evaluated.
Katsuya Narumi, Hiroki Ohya, Masaki Kobayashi, Yoshihiko Shibayama, Ken Iseki, Jiro Ogura   +5 more
openaire   +4 more sources

Anion transport in heart.

Physiological Reviews, 2000
Anion transport proteins in mammalian cells participate in a wide variety of cell and intracellular organelle functions, including regulation of electrical activity, pH, volume, and the transport of osmolites and metabolites, and may even play a role in ...
J. Hume, D. Duan, M. Collier, J. Yamazaki, B. Horowitz   +4 more
semanticscholar   +1 more source