Results 11 to 20 of about 69,379 (288)

Poxviral Ankyrin Proteins [PDF]

open access: yesViruses, 2015
Multiple repeats of the ankyrin motif (ANK) are ubiquitous throughout the kingdoms of life but are absent from most viruses. The main exception to this is the poxvirus family, and specifically the chordopoxviruses, with ANK repeat proteins present in all
Michael H. Herbert   +2 more
doaj   +3 more sources

Ankyrin‐2 genetic variants: A case of Ankyrin‐B syndrome [PDF]

open access: yesAnnals of Noninvasive Electrocardiology, 2022
Inherited cardiac arrhythmias (ICA) have become one of the leading causes of sudden cardiac death in people under 40 years old. Variants in the ankyrin‐B or ankyrin‐2 genes will result in several cardiac arrhythmias ranging from sinus node dysfunction to
Jin Song   +2 more
doaj   +3 more sources

Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels [PDF]

open access: yesMolecular Brain, 2019
Ankyrin B (AnkB) is an adaptor and scaffold for motor proteins and various ion channels that is ubiquitously expressed, including in the brain. AnkB has been associated with neurological disorders such as epilepsy and autism spectrum disorder, but ...
Catherine S. W. Choi   +5 more
doaj   +5 more sources

Ankyrins [PDF]

open access: yesFEBS Letters, 2000
This review is focused on ankyrin which is a protein linker between the integral membrane proteins and spectrin‐based cytoskeleton. Structure and distribution of different ankyrin isoforms that are products of alternative‐spliced genes are described. Interaction of ankyrins with various membranes is considered.
Rubtsov, Alexander M, Lopina, Olga D
openaire   +2 more sources

Evolutionary dissection of monkeypox virus: Positive Darwinian selection drives the adaptation of virus–host interaction proteins

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The emerging and ongoing outbreak of human monkeypox (hMPX) in 2022 is a serious global threat. An understanding of the evolution of the monkeypox virus (MPXV) at the single-gene level may provide clues for exploring the unique aspects of the current ...
Xiao-Yong Zhan, Gao-Feng Zha, Yulong He
doaj   +1 more source

Performance of Affinity-Improved DARPin Targeting HIV Capsid Domain in Interference of Viral Progeny Production

open access: yesBiomolecules, 2021
Previously, a designed ankyrin repeat protein, AnkGAG1D4, was generated for intracellular targeting of the HIV-1 capsid domain. The efficiency was satisfactory in interfering with the HIV assembly process.
Kanokporn Sornsuwan   +7 more
doaj   +1 more source

Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes

open access: yesJournal of Cardiovascular Development and Disease, 2021
The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart.
Drew Nassal   +6 more
doaj   +1 more source

AtTPR10 Containing Multiple ANK and TPR Domains Exhibits Chaperone Activity and Heat-Shock Dependent Structural Switching

open access: yesApplied Sciences, 2020
Among the several tetratricopeptide (TPR) repeat-containing proteins encoded by the Arabidopsis thaliana genome, AtTPR10 exhibits an atypical structure with three TPR domain repeats at the C-terminus in addition to seven ankyrin (ANK) domain repeats at ...
Seol Ki Paeng   +9 more
doaj   +1 more source

The toxins of vertically transmitted Spiroplasma

open access: yesFrontiers in Microbiology, 2023
Vertically transmitted (VT) microbial symbionts play a vital role in the evolution of their insect hosts. A longstanding question in symbiont research is what genes help promote long-term stability of vertically transmitted lifestyles.
Logan D. Moore, Matthew J. Ballinger
doaj   +1 more source

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