Results 21 to 30 of about 69,379 (288)

Broad-Spectrum Antiviral Activity of an Ankyrin Repeat Protein on Viral Assembly against Chimeric NL4-3 Viruses Carrying Gag/PR Derived from Circulating Strains among Northern Thai Patients

Viruses, 2018
Certain proteins have demonstrated proficient human immunodeficiency virus (HIV-1) life cycle disturbance. Recently, the ankyrin repeat protein targeting the HIV-1 capsid, AnkGAG1D4, showed a negative effect on the viral assembly of the HIV-1NL4-3 ...
Supachai Sakkhachornphop, Sudarat Hadpech, Tanchanok Wisitponchai, Chansunee Panto, Doungnapa Kantamala, Utaiwan Utaipat, Jutarat Praparattanapan, Wilai Kotarathitithum, Sineenart Taejaroenkul, Umpa Yasamut, Koollawat Chupradit, Sutpirat Moonmuang, Vannajan Sanghiran Lee, Khuanchai Suparatpinyo, Chatchai Tayapiwatana   +14 more
doaj   +1 more source

Ankyrin-R regulates fast-spiking interneuron excitability through perineuronal nets and Kv3.1b K+ channels

eLife, 2021
Neuronal ankyrins cluster and link membrane proteins to the actin and spectrin-based cytoskeleton. Among the three vertebrate ankyrins, little is known about neuronal Ankyrin-R (AnkR). We report AnkR is highly enriched in Pv+ fast-spiking interneurons in
Sharon R Stevens, Colleen M Longley, Yuki Ogawa, Lindsay H Teliska, Anithachristy S Arumanayagam, Supna Nair, Juan A Oses-Prieto, Alma L Burlingame, Matthew D Cykowski, Mingshan Xue, Matthew N Rasband   +10 more
doaj   +1 more source

Posttranslational control of membrane-skeleton (ankyrin and alpha beta- spectrin) assembly in early myogenesis [PDF]

, 1985
Adult chicken skeletal muscle cells express polypeptides that are antigenically related to alpha-spectrin (Mr 240,000) and beta-spectrin (Mr 220,000-225,000), the major components of the erythrocyte membrane- skeleton, and to ankyrin (Mr 237,000; also ...
Lazarides, Elias, Nelson, W. James
core   +1 more source

Giant ankyrin-G regulates cardiac function [PDF]

Journal of Biological Chemistry, 2021
Cardiovascular disease (CVD) remains the most common cause of adult morbidity and mortality in developed nations. As a result, predisposition for CVD is increasingly important to understand. Ankyrins are intracellular proteins required for the maintenance of membrane domains.
Omer Cavus, Jordan Williams, Hassan Musa, Mona El Refaey, Dan Gratz, Rebecca Shaheen, Neill A. Schwieterman, Sara Koenig, Steve Antwi-Boasiako, Lindsay J. Young, Xianyao Xu, Mei Han, Loren E. Wold, Thomas J. Hund, Peter J. Mohler, Elisa A. Bradley   +15 more
openaire   +2 more sources

Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover. [PDF]

, 2012
Protein turnover through cullin-3 is tightly regulated by posttranslational modifications, the COP9 signalosome, and BTB/POZ-domain proteins that link cullin-3 to specific substrates for ubiquitylation.
Chen, Ju, Lange, Stephan, Perera, Sue, Teh, Phildrich   +3 more
core   +2 more sources

Reciprocal interactions between cell adhesion molecules of the immunoglobulin superfamily and the cytoskeleton in neurons

Frontiers in Cell and Developmental Biology, 2016
Cell adhesion molecules of the immunoglobulin superfamily (IgSF) including the neural cell adhesion molecule (NCAM) and members of the L1 family of neuronal cell adhesion molecules play important functions in the developing nervous system by regulating ...
Vladimir eSytnyk, Iryna eLeshchyns'Ka
doaj   +1 more source

The L1 cell adhesion molecule constrains dendritic spine density in pyramidal neurons of the mouse cerebral cortex

Frontiers in Neuroanatomy, 2023
A novel function for the L1 cell adhesion molecule, which binds the actin adaptor protein Ankyrin was identified in constraining dendritic spine density on pyramidal neurons in the mouse neocortex.
Kelsey E. Murphy, Kelsey E. Murphy, Sarah D. Wade, Sarah D. Wade, Justin E. Sperringer, Justin E. Sperringer, Vishwa Mohan, Vishwa Mohan, Bryce W. Duncan, Bryce W. Duncan, Erin Y. Zhang, Erin Y. Zhang, Yubin Pak, Yubin Pak, David Lutz, Melitta Schachner, Patricia F. Maness, Patricia F. Maness   +17 more
doaj   +1 more source

Identification of calpain cleavage sites in the G1 cyclin-dependent kinase inhibitor p19(INK4d) [PDF]

, 2006
Calpains are a large family of Ca2+-dependent cysteine proteases that are ubiquitously distributed across most cell types and vertebrate species. Calpains play a role in cell differentiation, apoptosis, cytoskeletal remodeling, signal transduction and ...
Croall, Dayton, Fischer, Fuchs, Goll, Harris, Inomata, Kuboki, Lee, Molinari, Nicotera, Ruas, Sasaki, Smialowski   +13 more
core   +2 more sources

Mechanical Anisotropy of Ankyrin Repeats [PDF]

Biophysical Journal, 2012
Red blood cells are frequently deformed and their cytoskeletal proteins such as spectrin and ankyrin-R are repeatedly subjected to mechanical forces. While the mechanics of spectrin was thoroughly investigated in vitro and in vivo, little is known about the mechanical behavior of ankyrin-R.
Lee, W, Zeng, X, Rotolo, K, Yang, M, Schofield, C, Bennett, V, Yang, W, Marszalek, P   +7 more
openaire   +3 more sources

Control of erythroid differentiation: asynchronous expression of the anion transporter and the peripheral components of the membrane skeleton in AEV- and S13-transformed cells [PDF]

, 1986
Chicken erythroblasts transformed with avian erythroblastosis virus or S13 virus provide suitable model systems with which to analyze the maturation of immature erythroblasts into erythrocytes.
Boyer, Brigitte, Lazarides, Elias, Vogt, Peter K., Woods, Catherine M.   +3 more
core   +1 more source