Results 31 to 40 of about 34,339 (250)
A study of annexin A2 and implantation
, 2014 Implantation is a critical step in reproduction. It is complicated and well-coordinated consisting of apposition, attachment and invasion of embryo into the endometrium. The mechanism of implantation is unclear. Our previous proteomic study showed an increase of annexin A2 in the endometrium during the implantation window of mice, consistent with the ...
Bing Wang
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Annexin A2 promotes angiogenesis after ischemic stroke via annexin A2 receptor – AKT/ERK pathways [PDF]
Neuroscience Letters, 2021 Abstract Promoting angiogenesis to restore circulation to the ischemic tissue is still an important therapeutic target in stroke. Here, we ask whether the Ca2+-regulated, phospholipid-and membrane-binding protein-Annexin A2 (ANXA2) may regulate angiogenesis after stroke.Compared with wild type (WT) mice, the density of microvessels in brain and
Wenlu Li +7 more
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Frontiers in Genetics, 2023 Background: Annexin A2 (ANXA2) belongs to the Annexin A family and plays a role in epithelial-mesenchymal transition, fibrinolysis, and other physiological processes. Annexin A2 has been extensively implicated in tumorigenesis and development in previous
Yijie Ning, Yufei Li, Hongqin Wang
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Annexin A2 in Fibrinolysis, Inflammation and Fibrosis [PDF]
International Journal of Molecular Sciences, 2021 As a cell surface tissue plasminogen activator (tPA)-plasminogen receptor, the annexin A2 (A2) complex facilitates plasmin generation on the endothelial cell surface, and is an established regulator of hemostasis. Whereas A2 is overexpressed in hemorrhagic disease such as acute promyelocytic leukemia, its underexpression or impairment may result in ...
Lim, Hana I., Hajjar, Katherine A.
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The Annexin A2/S100A10 Complex: The Mutualistic Symbiosis of Two Distinct Proteins
Biomolecules, 2021 Mutualistic symbiosis refers to the symbiotic relationship between individuals of different species in which both individuals benefit from the association.
Alamelu Bharadwaj +2 more
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Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury. [PDF]
Mol Cell ProteomicsTian X +5 more
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Annexin A2 Regulates TRPA1-Dependent Nociception [PDF]
The Journal of Neuroscience, 2014 The transient receptor potential A1 (TRPA1) channel is essential for vertebrate pain. Even though TRPA1 activation by ligands has been studied extensively, the molecular machinery regulating TRPA1 is only poorly understood. Using an unbiased proteomics-based approach we uncovered the physical association of Annexin A2 (AnxA2) with native TRPA1 in mouse
Luca Avenali +6 more
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Annexin A1 and A2: roles in retrograde trafficking of Shiga toxin. [PDF]
PLoS ONE, 2012 Annexins constitute a family of calcium and membrane binding proteins. As annexin A1 and A2 have previously been linked to various membrane trafficking events, we initiated this study to investigate the role of these annexins in the uptake and ...
Lionel Tcatchoff +7 more
doaj +1 more source
Viruses, 2022 Encephalomyocarditis virus can cause myocarditis and encephalitis in pigs and other mammals, thus posing a potential threat to public health safety. The 2A protein is an important virulence factor of EMCV.
Ruochan Han +4 more
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Diagnostic Value of Plasma Annexin A2 in Early-Stage High-Grade Serous Ovarian Cancer
Diagnostics, 2021 Ovarian cancer (OC) is commonly diagnosed at advanced stage when prognosis is poor. Consequently, there is an urgent clinical need to identify novel biomarkers for early detection to improve survival.
Noor A. Lokman +5 more
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