Results 21 to 30 of about 243,891 (236)

Annexin A2 in Tumors of the Gastrointestinal Tract, Liver, and Pancreas. [PDF]

Cancers (Basel)
Simple Summary Annexin A2 is a protein that plays a role in many important cell functions, but when its levels are not properly regulated, it can contribute to the development of cancer, particularly in the digestive system.
Christofidis K, Pergaris A, Fioretzaki R, Charalampakis N, Kapetanakis EΙ, Kavantzas N, Schizas D, Sakellariou S.   +7 more
europepmc   +2 more sources

Ca²⁺ ions facilitate the organization of the Annexin A2/S100A10 heterotetramer. [PDF]

Proteins, 2023
Annexin A2 (A2) is a member of the Annexin family, which contains Ca2+‐regulated phospholipid‐binding proteins. Annexins associate with S100 proteins to form heterotetramers.
Lindsay S, Bartolotti L, Li Y.
europepmc   +2 more sources

Açaí (Euterpe oleracea Mart.) Seed Oil Exerts a Cytotoxic Role over Colorectal Cancer Cells: Insights of Annexin A2 Regulation and Molecular Modeling

Metabolites, 2023
Açaí, Euterpe oleracea Mart., is a native plant from the Amazonian and is rich in several phytochemicals with anti-tumor activities. The aim was to analyze the effects of açaí seed oil on colorectal adenocarcinoma (ADC) cells.
Marcos Antonio Custódio Neto da Silva, Josiane Weber Tessmann, Kátia Regina Assunção Borges, Laís Araújo Souza Wolff, Fernanda Diniz Botelho, Leandro Alegria Vieira, Jose Andres Morgado-Diaz, Tanos Celmar Costa Franca, Maria do Carmo Lacerda Barbosa, Maria do Desterro Soares Brandão Nascimento, Murilo Ramos Rocha, João Ernesto de Carvalho   +11 more
doaj   +2 more sources

Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface

Frontiers in Oncology
BackgroundOur earlier research revealed that the secreted lysyl oxidase-like 4 (LOXL4) that is highly elevated in triple-negative breast cancer (TNBC) acts as a catalyst to lock annexin A2 on the cell membrane surface, which accelerates invasive ...
Tetta Takahashi, Tetta Takahashi, Nahoko Tomonobu, Rie Kinoshita, Ken-ichi Yamamoto, Hitoshi Murata, Ni Luh Gede Yoni Komalasari, Youyi Chen, Fan Jiang, Yuma Gohara, Toshiki Ochi, Toshiki Ochi, I Made Winarsa Ruma, I Wayan Sumardika, Jin Zhou, Tomoko Honjo, Yoshihiko Sakaguchi, Akira Yamauchi, Futoshi Kuribayashi, Eisaku Kondo, Yusuke Inoue, Junichiro Futami, Shinichi Toyooka, Yoshito Zamami, Masakiyo Sakaguchi   +24 more
doaj   +2 more sources

Encephalomyocarditis Virus 2A Protein Inhibited Apoptosis by Interaction with Annexin A2 through JNK/c-Jun Pathway

Viruses, 2022
Encephalomyocarditis virus can cause myocarditis and encephalitis in pigs and other mammals, thus posing a potential threat to public health safety. The 2A protein is an important virulence factor of EMCV.
Ruochan Han, Lin Liang, Tong Qin, Sa Xiao, Ruiying Liang   +4 more
doaj   +2 more sources

Annexin A2 in Virus Infection [PDF]

Frontiers in Microbiology, 2018
Viral life cycles consist of three main phases: (1) attachment and entry, (2) genome replication and expression, and (3) assembly, maturation, and egress.
Julia R. Taylor, Joseph G. Skeate, W. Martin Kast, W. Martin Kast, W. Martin Kast   +4 more
doaj   +3 more sources

Annexin A2 [PDF]

Stroke, 2010
Hemorrhagic transformation, incomplete reperfusion, neurotoxicity, and the short treatment time window comprise major challenges for thrombolytic therapy. Improving tissue plasminogen activator therapy has become one of the highest priorities in the stroke field.
Xiang, Fan, Zhanyang, Yu, Jianxiang, Liu, Ning, Liu, Katherine A, Hajjar, Karen L, Furie, Eng H, Lo, Xiaoying, Wang   +7 more
openaire   +3 more sources

A novel DNA aptamer targeting lung cancer stem cells exerts a therapeutic effect by binding and neutralizing Annexin A2

Molecular Therapy: Nucleic Acids, 2022
Cancer remains one of the leading causes of death worldwide. Cancer stem cells (CSCs) are the underlying reason for tumor recurrence, progression, and therapeutic resistance.
Yi-Ying Wu, I-Shan Hsieh, Chia-Hao Tung, Chen-Hsun Weng, Jia-En Wu, Jau-Song Yu, Tse-Ming Hong, Yuh-Ling Chen   +7 more
doaj   +2 more sources

Ubiquitinated annexin A2 is enriched in the cytoskeleton fraction [PDF]

FEBS Letters, 2004
Annexin A2 is a multifunctional protein and its cellular functions are regulated by post‐translational modifications and ligand binding. When purified from porcine intestinal mucosa and transformed mouse Krebs II cells, SDS–PAGE revealed high‐molecular‐mass forms in addition to the 36 kDa protomer.
Lauvrak, Silje U., Hollås, Hanne, Døskeland, Anne P., Aukrust, Ingvild, Flatmark, Torgeir, Vedeler, Anni   +5 more
openaire   +3 more sources

Annexin A2 combined with TTK accelerates esophageal cancer progression via the Akt/mTOR signaling pathway. [PDF]

Cell Death Dis
Annexin A2 (ANXA2) is a widely reported oncogene. However, the mechanism of ANXA2 in esophageal cancer is not fully understood. In this study, we provided evidence that ANXA2 promotes the progression of esophageal squamous cell carcinoma (ESCC) through ...
Liu R, Lu Y, Li J, Yao W, Wu J, Chen X, Huang L, Nan D, Zhang Y, Chen W, Wang Y, Jia Y, Tang J, Liang X, Zhang H.   +14 more
europepmc   +2 more sources