Results 151 to 160 of about 2,972 (170)

Involvement of TRPV1-ANO1 Interactions in Pain-Enhancing Mechanisms

2018
Primary sensory neurons detect potentially dangerous environmental situations via many "sensor" proteins located on the plasma membrane. Although receptor-type cation channels are thought to be the major sensors in sensory neurons, anion channels are also important players in the peripheral nervous system.
Y, Takayama, Makoto, Tominaga
openaire   +2 more sources

Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1

Cellular Signalling, 2018
Airway epithelial cells express both Ca2+ activated TMEM16A/ANO1 and cAMP activated CFTR anion channels. Previous work suggested a significant crosstalk of intracellular Ca2+ and cAMP signaling pathways, leading to activation of both chloride channels.
Joana Lérias, Madalena Pinto, Roberta Benedetto, Rainer Schreiber, Margarida Amaral, Massimo Aureli, Karl Kunzelmann   +6 more
openaire   +2 more sources

Functional analysis of the antisense long noncoding RNA ANO1-AS2 and the ANO1 gene in Iraqi men with idiopathic infertility

Asia Pacific Journal of Molecular Biology and Biotechnology
The leading causes of male infertility remain unclear. Men with average semen analysis results are diagnosed with idiopathic infertility. The ANO1-AS2 gene is a long noncoding RNA located close to the anoctamin1 (ANO1) gene. ANO1 regulates calcium-activated chloride channels, which regulate many cellular processes.
Shimaa Jumaa Abood, Maan Hasan Salih, Mohammad Mutlag Salih   +2 more
openaire   +1 more source

Characterization of Ano1 expressing cells in the mouse corpus cavernosum

Physiology
Background/objectives: Highly coordinated contraction and relaxation of smooth muscle cells (SMCs) is critical to penile function. The Ca2+-activated Cl− channel, Anoctamin-1 (Ano1) plays a role in this as antagonists of this channel inhibit contractile, electrical and intracellular Ca2+ activity. mRNA encoding Ano1 is highly expressed in whole rabbit
Karen Hannigan, Emily Fox, Caroline Cobine   +2 more
openaire   +1 more source

ANO1 regulates cardiac fibrosis via ATI-mediated MAPK pathway

Cell Calcium, 2020
Xiangqin Tian, Changye Sun, Xianwei Wang   +2 more
exaly  

High level of ANO1 promotes pancreatic cancer growth in concert with oncogenic KRAS

Molecular Biology Reports, 2023
Yihua Qian, Meiyan Sun, Sun Meiyan
exaly  

S2060 Ano1 Plays a Role in the Proliferation of ICC

Gastroenterology, 2010
Jennifer E. Stanich, Simon J. Gibbons, Jason R. Rock, Brian D. Harfe, Tamas Ordog, Gianrico Farrugia   +5 more
openaire   +1 more source

Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers

European Journal of Medicinal Chemistry, 2020
Seongshick Ryu, Chiman Song, Injae Shin   +2 more
exaly  

114 Altered Expression of Ano1 Variants in Gastroparesis

Gastroenterology, 2010
Amelia Mazzone, Cheryl E. Bernard, Luis J. Galietta, Pankaj J. Pasricha, David R. Linden, Joseph H. Szurszewski, Tamas Ordog, Simon J. Gibbons, Gianrico Farrugia   +8 more
openaire   +1 more source

Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors

European Journal of Medicinal Chemistry, 2018
Yohan Seo, Jiwon Chang, Seong Soon Kim
exaly