Results 151 to 160 of about 2,978 (169)
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Compartmentalized crosstalk of CFTR and TMEM16A (ANO1) through EPAC1 and ADCY1

Cellular Signalling, 2018
Airway epithelial cells express both Ca2+ activated TMEM16A/ANO1 and cAMP activated CFTR anion channels. Previous work suggested a significant crosstalk of intracellular Ca2+ and cAMP signaling pathways, leading to activation of both chloride channels.
Joana Lérias   +6 more
openaire   +2 more sources

Characterization of Ano1 expressing cells in the mouse corpus cavernosum

Physiology
Background/objectives: Highly coordinated contraction and relaxation of smooth muscle cells (SMCs) is critical to penile function. The Ca2+-activated Cl− channel, Anoctamin-1 (Ano1) plays a role in this as antagonists of this channel inhibit contractile, electrical and intracellular Ca2+ activity. mRNA encoding Ano1 is highly expressed in whole rabbit
Karen Hannigan   +2 more
openaire   +1 more source

VI-116, A Novel Potent Inhibitor of VRAC with Minimal Effect on ANO1

International Journal of Molecular Sciences, 2022
Ikyon Kim, Dongkyu Jeon, Wan Namkung
exaly  

ANO1 regulates cardiac fibrosis via ATI-mediated MAPK pathway

Cell Calcium, 2020
Ke-Tao Ma, Junqiang Si, Yuqiao Chang
exaly  

Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers

European Journal of Medicinal Chemistry, 2020
Jae-Yong Park   +2 more
exaly  

High level of ANO1 promotes pancreatic cancer growth in concert with oncogenic KRAS

Molecular Biology Reports, 2023
Meiyan Sun, Sun Meiyan
exaly  

S2060 Ano1 Plays a Role in the Proliferation of ICC

Gastroenterology, 2010
Jennifer E. Stanich   +5 more
openaire   +1 more source

114 Altered Expression of Ano1 Variants in Gastroparesis

Gastroenterology, 2010
Amelia Mazzone   +8 more
openaire   +1 more source

Synthesis and biological evaluation of novel Ani9 derivatives as potent and selective ANO1 inhibitors

European Journal of Medicinal Chemistry, 2018
Ikyon Kim, Wan Namkung, Seong Soon Kim
exaly  

Variomics Screen Identifies the Re-entrant Loop of the Calcium-activated Chloride Channel ANO1 That Facilitates Channel Activation

Journal of Biological Chemistry, 2015
Michiel Van Diepen   +2 more
exaly  

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