This study optimizes a two‐step induction system to generate PGCLCs from chicken ESCs. The induced cells express germline markers and migrate to gonads in ovo, offering a novel approach for avian genetic resource conservation. Primordial germ cells (PGCs) are the progenitor cells of sperm and eggs.
Zeyu Li +10 more
wiley +1 more source
Chimeric antigen receptor cells as a tool for localized delivery of TNFα in solid cancer treatment. [PDF]
Yao Z, Sittplangkoon C.
europepmc +1 more source
Two new non‐competitive mGlu1 receptor antagonists are potent tools to unravel functions of this mGlu receptor subtype [PDF]
Thomas Knöpfel
openalex +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Editorial: Case reports in psychopharmacology, volume III. [PDF]
Stuhec M, Di Ciano P.
europepmc +1 more source
Antagonistic K/Mg ratios: is foliar application of MgSO4 a superior alternative to root resupply? [PDF]
Jasper Lauritz Dölger +2 more
openalex +1 more source
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti +8 more
wiley +1 more source
RETRACTED: Sudha et al. Triazole Modified Tetraiodothyroacetic Acid Conjugated to Polyethylene Glycol, a Thyrointegrin α<sub>v</sub>β<sub>3</sub> Antagonist as a Radio- and Chemo-Sensitizer in Pancreatic Cancer. <i>Biomedicines</i> 2022, <i>10</i>, 795. [PDF]
Sudha T, Godugu K, Glinsky GV, Mousa SA.
europepmc +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source

