Results 41 to 50 of about 48,914 (162)

Assessment of anthracycline-induced long-term cardiotoxicity in patients with hematological malignancies

Iraqi Journal of Hematology, 2019
BACKGROUND: Anthracyclines are antibiotic antineoplastic drugs used in the treatment of various hematological and solid malignancies. They are well-known for their cardiotoxic side effects which are related to their cumulative dosages.
Aws Sabah Al-Rubaye, Ahmed S Noori, Tareq Abdullah Saleh, Ibrahim Khalil Ibrahim   +3 more
doaj   +1 more source

Prognosis Prediction of Cardiovascular Event With Glucose‐Albumin Ratio on Patients With Cancer and Prescribed With Anthracycline

Cancer Medicine
Aims This study aimed to investigate the clinical value of the glucose‐albumin ratio (GAR) in predicting the prognosis of cancer patients prescribed anthracycline‐based chemotherapy.
Iokfai Cheang, Ying Li, Xu Zhu, Ziqi Chen, Qing‐Wen Ren, Mei‐Zhen Wu, Xin Xu, Hung‐Fat Tse, Kai‐Hang Yiu, Xinli Li   +9 more
doaj   +1 more source

Subclinical Cardiac Dysfunction in Childhood Cancer Survivors on 10-Years Follow-Up Correlates With Cumulative Anthracycline Dose and Is Best Detected by Cardiopulmonary Exercise Testing, Circulating Serum Biomarker, Speckle Tracking Echocardiography, and Tissue Doppler Imaging

Frontiers in Pediatrics, 2020
Background: Survivors of childhood cancer are at risk for anthracycline- and/or radiotherapy-induced cardiotoxicity.Aims: The aim of this study was to assess clinical, laboratory, and imaging parameters of subclinical cardiovascular disease in childhood ...
Cordula Maria Wolf, Barbara Reiner, Barbara Reiner, Andreas Kühn, Alfred Hager, Jan Müller, Jan Müller, Christian Meierhofer, Renate Oberhoffer, Renate Oberhoffer, Peter Ewert, Irene Schmid, Jochen Weil   +12 more
doaj   +1 more source

Deficits in the IgG+ memory B‐cell recovery after anthracycline treatment is confined to the spleen of rhesus macaques

Clinical & Translational Immunology, 2020
Objectives Loss of vaccine‐induced antibodies (Abs) after chemotherapy against paediatric acute lymphoblastic leukaemia (ALL) is common and often necessitates re‐immunisation after cessation of treatment.
Gintare Lasaviciute, Andréas L Bricaud, Fredrika Hellgren, Hanna M Ingelman‐Sundberg, Staffan Eksborg, Margreet Jonker, Krista G Haanstra, Ida Hed Myrberg, Eva Sverremark‐Ekström, Karin Loré, Shanie Saghafian‐Hedengren, Anna Nilsson   +11 more
doaj   +1 more source

Editorial: Novel mechanisms, imaging approaches, and management strategies for anthracycline-induced cardiotoxicity

Frontiers in Cardiovascular Medicine, 2023
René R. Sevag Packard, René R. Sevag Packard, René R. Sevag Packard, René R. Sevag Packard, René R. Sevag Packard, René R. Sevag Packard, René R. Sevag Packard, Eric H. Yang, Eric H. Yang, Eric H. Yang, Eric H. Yang   +10 more
doaj   +1 more source

Predictive Value of Baseline Left Ventricular Global Longitudinal Strain for Cardiac Dysfunction in Patients with Moderate to High Risk of Cancer Therapy-Related Cardiovascular Toxicity

Pharmaceuticals
Background: Anthracycline-based chemotherapy is associated with a risk of cancer therapy-related cardiac dysfunction (CTRCD), particularly in patients with moderate to high cardiovascular risk.
Anna Borowiec, Patrycja Ozdowska, Magdalena Rosinska, Agnieszka Maria Zebrowska, Slawomir Jasek, Beata Kotowicz, Hanna Kosela-Paterczyk, Elzbieta Lampka, Zbigniew Nowecki, Jan Walewski   +9 more
doaj   +1 more source

Temporal Dynamics of Extracellular Matrix Remodeling in Anthracycline-Induced Cardiotoxicity

Cells
Anthracyclines are widely used chemotherapeutic agents with proven efficacy against a broad range of malignancies, but their clinical utility is limited by a well-documented, dose-dependent cardiotoxicity.
Fibi Meshrkey, Somaya Y. Ibrahim, Rushita A. Bagchi, William J. Richardson   +3 more
doaj   +1 more source

XMU-MP-1, the Hippo Signaling Pathway MST-1 Kinase Inhibitor, Prevents the Development of Drug Resistance to Doxorubicin in Hematological Tumor Cells

Pharmaceuticals
Background/Objectives: The search for new drugs which could suppress drug resistance development in tumor cells is extremely important for clinical practice.
Alexander G. Stepchenko, Elizaveta V. Pankratova   +1 more
doaj   +1 more source

Genetic polymorphisms in the development of anthracycline-induced cardiovascular toxicity in patients with follicular lymphoma

Рациональная фармакотерапия в кардиологии
Aim. To identify genetic variants associated with the risk of developing anthracycline-induced cardiovascular toxicity during antitumor therapy in patients with follicular lymphoma.Material and methods.
G. R. Gimatdinova, O. E. Danilova, Y. N. Milyutkina, A. S. Sustretov, P. V. Ilyasov, I. L. Davydkin   +5 more
doaj   +1 more source

Early Myocardial Strain Reduction and miR-122-5p Elevation Associated with Interstitial Fibrosis in Anthracycline-Induced Cardiotoxicity

Biomedicines
Echocardiographic myocardial strain is crucial for early detection of anthracycline-induced cardiotoxicity, particularly in patients at moderate or high risk.
María de Regla Caballero-Valderrama, Elisa Bevilacqua, Miriam Echevarría, Francisco Javier Salvador-Bofill, Antonio Ordóñez, José Eduardo López-Haldón, Tarik Smani, Eva M. Calderón-Sánchez   +7 more
doaj   +1 more source