Anthrax Toxin Receptor 2 Determinants that Dictate the pH Threshold of Toxin Pore Formation [PDF]
, 2011 The anthrax toxin receptors, ANTXR1 and ANTXR2, act as molecular clamps to prevent the protective antigen (PA) toxin subunit from forming pores until exposure to low pH.
Collier, R. John +5 more
core +1 more source
Identification of Bacteria by Patterns Generated from Odor Spectra [PDF]
Sensors and Actuators B 142 (2009) pp. 429-434, 2009 We use the power density spectra obtained by fluctuation-enhanced sensing of bacterial odors (Escherichia coli and Anthrax-surrogate Bacillus subtilis) to generate new, highly distinguishable, types of patterns based on the average slope of the spectra in different frequency ranges.
arxiv
Endocytic recycling and vesicular transport systems mediate transcytosis of Leptospira interrogans across cell monolayer. [PDF]
, 2019 Many bacterial pathogens can cause septicemia and spread from the bloodstream into internal organs. During leptospirosis, individuals are infected by contact with Leptospira-containing animal urine-contaminated water.
Fang, Jia-Qi +7 more
core +1 more source
The envenomation of general physiology throughout the last century. [PDF]
, 2017 Toxins are the poisonous products of organisms. Toxins serve vital defensive and offensive functions for those that harbor them: stinging scorpions, pesticidal plants, sanguinary snakes, fearless frogs, sliming snails, noxious newts, and smarting spiders.
Sack, Jon T
core +1 more source
Endothelial anthrax toxin receptor 2 plays a protective role in liver fibrosis. [PDF]
Front Cell Dev Biol, 2023 Huang X +7 more
europepmc +1 more source
Calmodulin in Complex with Proteins and Small Molecule Ligands: Operating with the Element of Surprise. Implications for Structure-Based Drug Design [PDF]
, 2009 Calmodulin plays a role in several life processes, its flexibility allows binding of a number of different ligands from small molecules to amphiphilic peptide helices and proteins. Through the diversity of its functions, it is quite difficult to find new
Keserű, György Miklós +2 more
core
Anthrax lethal toxin exerts potent metabolic inhibition of the cardiovascular system
mBioBacillus anthracis causes anthrax through a combination of bacterial infection and toxemia. As a major virulence factor of B. anthracis, anthrax lethal toxin (LT) is a zinc-dependent metalloproteinase, exerting its cytotoxicity through proteolytic ...
Jie Liu +5 more
doaj +1 more source
Treatment of ovarian cancer with modified anthrax toxin. [PDF]
Proc Natl Acad Sci U S A, 2022 Aktories K.
europepmc +1 more source
Anthrax toxins and the host: a story of intimacy
Cellular Microbiology, 2003 Although the dramatic events of the year 2001 have revitalized the interest in anthrax, research on Bacillus anthracis and its major virulence factors is one of the oldest theme in microbiology and started with the early works of Robert Koch and Louis Pasteur. The anthrax toxins are central to anthrax pathogenesis. They were discovered in the mid-1950s
Michèle Mock, Tâm Mignot
openaire +3 more sources
Fluctuation-Enhanced Sensing of Bacterium Odors [PDF]
arXiv, 2009 The goal of this paper is to explore the possibility to detect and identify bacteria by sensing their odor via fluctuation-enhanced sensing with commercial Taguchi sensors. The fluctuations of the electrical resistance during exposure to different bacterial odors, Escherichia coli and anthrax-surrogate Bacillus subtilis, have been measured and analyzed.
arxiv