Results 111 to 120 of about 131,343 (218)

Utility of Anti-Carbamylated Antibodies in Early Rheumatoid Arthritis in South Asian Population

Journal of Clinical Rheumatology and Immunology
Background: This study aimed to evaluate the correlation of anti-carbamylated protein (anti-CarP) antibodies with disease activity in Rheumatoid Arthritis (RA) patients, stratified by Rheumatoid Factor (RF) and/or anti-citrullinated peptide antibodies ...
Chandhu A S, Josna Joseph, John Mathew
doaj   +1 more source

An autoantibody profile identified by human genome‐wide protein arrays in rheumatoid arthritis

MedComm, Volume 5, Issue 8, August 2024.
HuProt array is a genome‐wide protein array suitable for high throughput unbiased analysis of autoantibodies against the entire human proteome without protein modifications. We performed RA autoantibody screening in 182 RA patients and 261 controls with HuProt arrays to identify the nonmodified protein antibody profile of RA, especially in ACPA ...
Xu Liu, Xiaoying Zhang, Yu‐Jian Kang, Fei Huang, Shuang Liu, Yixue Guo, Yingni Li, Changcheng Yin, Mingling Liu, Qimao Han, Qingwen Wang, Hua Ye, Haihong Yao, Chun Li, Jiahe Li, Wangzha Pingcuo, Yan Zhang, Yin Su, Ge Gao, Zhanguo Li, Xiaolin Sun   +20 more
wiley   +1 more source

Studies on the role of autoantibodies and autoantigens in rheumatoid arthritis and myositis [PDF]

, 2016
A major population of patients affected with rheumatoid arthritis (RA) and inflammatory idiopathic myopathies (IIM, collectively called myositis) is characterized by the presence of autoantibodies.
Cerqueira, Cátia
core   +1 more source

A predominant involvement of the triple seropositive patients and others with rheumatoid factor in the association of smoking with rheumatoid arthritis [PDF]

, 2020
The major environmental risk factor for rheumatoid arthritis (RA) is smoking, which according to a widely accepted model induces protein citrullination in the lungs, triggering the production of anticitrullinated protein antibodies (ACPA) and RA ...
Alejandro Balsa, Alejandro Villalba, Alfonso Corrales, Ana M. Ortiz, Ana Martínez-Feito, Ana Triguero-Martinez, Antonio Mera-Varela, Benjamín Fernandez-Gutierrez, Carmen Conde, Cristina Regueiro, Eva Herranz, Eva Perez-Pampin, González-Gay Mantecón, Miguel Ángel, Isidoro Gonzalez-Alvaro, Laura Nuño, Luis Rodriguez-Rodriguez, Lydia Abasolo, Raquel Lopez-Mejias, Sara Remuzgo-Martínez, Yolanda Lopez-Golan   +19 more
core   +1 more source

Redox Pathogenesis in Rheumatic Diseases

ACR Open Rheumatology, Volume 6, Issue 6, Page 334-346, June 2024.
Despite being some of the most anecdotally well‐known roads to pathogenesis, the mechanisms governing autoimmune rheumatic diseases are not yet fully understood. The overactivation of the cellular immune system and the characteristic development of autoantibodies have been linked to oxidative stress.
Olivia T. Laniak, Thomas Winans, Akshay Patel, Joy Park, Andras Perl   +4 more
wiley   +1 more source

Relation of cytokine profile and antibody values to post-translational protein modifications in patients with rheumatoid arthritis (preliminary data)

Научно-практическая ревматология
The aim of the study was to investigate the relationship between cytokine levels and values of antibodies to cyclic citrullinated peptide (anti-CCP) and antibodies to carbamylated proteins (anti-CarP) in patients with rheumatoid arthritis (RA). Materials
D. А. Dibrov, А. S. Avdeeva, М. Е. Diatroptov, V. V. Rybakova, Е. L. Nasonov   +4 more
doaj   +1 more source

The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical

Arthritis Research & Therapy, 2017
Background Rheumatoid arthritis (RA) consists of two syndromes, one autoantibody-positive and one autoantibody-negative. Existing data on the relation between age of onset and prevalence of autoantibodies were conflicting.
Debbie M. Boeters, Lukas Mangnus, Sofia Ajeganova, Elisabet Lindqvist, Björn Svensson, René E. M. Toes, Leendert A. Trouw, Tom W. J. Huizinga, Francis Berenbaum, Jacques Morel, Solbritt Rantapää-Dahlqvist, Annette H. M. van der Helm-van Mil   +11 more
doaj   +1 more source

Repurposing of rituximab biosimilars to treat B cell mediated autoimmune diseases

The FASEB Journal, Volume 38, Issue 5, 15 March 2024.
B cell functions include: (A) acting as antigen‐presenting cells (APCs) through B‐cell antigen receptors (BCRs), (B) interacting with T cells via the major histocompatibility complex class II (MHC II) and T‐cell receptors (TCRs), (C) producing autoantibodies, and (D) producing inflammatory cytokines.
Agata Mostkowska, Guy Rousseau, Noël J‐M Raynal   +2 more
wiley   +1 more source

In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response

Arthritis Research & Therapy, 2019
Background Rheumatoid arthritis (RA) is characterized by the presence of autoantibodies like rheumatoid factor (RF), anti-cyclic citrullinated peptide-2 (anti-CCP2), and anti-carbamylated protein (anti-CarP) antibodies.
Emma C. de Moel, Veerle F. A. M. Derksen, Leendert A. Trouw, Holger Bang, Gerard Collée, Leroy R. Lard, Sofia Ramiro, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude   +10 more
doaj   +1 more source

Laboratory diagnostics and pathogenesis of rheumatoid arthritis — the past and the present [PDF]

, 2018
Rheumatoid arthritis (RA) is one of the most common systemic connective tissue diseases of autoimmune origin and is characterised by chronic inflammation of joints. The aetiology of this disease has not been fully understood yet.
Kuligowska-Prusińska, Magdalena, Odrowąż-Sypniewska, Grazyna   +1 more
core   +2 more sources