Results 121 to 130 of about 131,343 (218)

Rheumatoid arthritis – usage of biomarkers in disease’ prognosing, diagnosing and monitoring

Quality in Sport
Introduction: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease which has a significant, negative influence of patients’ quality of daily life. In routine clinical practice there is a usage of classic biomarkers, such as rheumatoid factor
Sabina Skrzynecka, Hanna Pietruszewska, Oliwia Sędziak, Natalia Kruszewska, Urszula Borucińska   +4 more
doaj   +1 more source

Erythropoietin and a nonerythropoietic peptide analog promote aortic endothelial cell repair under hypoxic conditions: role of nitric oxide [PDF]

, 2016
The cytoprotective effects of erythropoietin (EPO) and an EPO-related nonerythropoietic analog, pyroglutamate helix B surface peptide (pHBSP), were investigated in an in vitro model of bovine aortic endothelial cell injury under normoxic (21% O2) and ...
Feelisch, Martin, Ferns, Gordon A A, Ghezzi, Pietro, Heikal, Lamia, Mengozzi, Manuela, Stelmaszczuk, Blanka   +5 more
core   +2 more sources

From patients with arthralgia, pre-RA and recently diagnosed RA: What is the current status of understanding RA pathogenesis? [PDF]

, 2018
It is believed that therapy for rheumatoid arthritis (RA) is the most effective and beneficial within a short time frame around RA diagnosis. This insight has caused a shift from research in patients with established RA to patients at risk of developing ...
Hazes, J.M.W. (Mieke), Lubberts, E.W. (Erik), Molendijk, M. (Marlieke)   +2 more
core   +1 more source

AB1277 PREVALENCE OF THE DIFFERENT ANTI-CARBAMYLATED PROTEIN ANTIBODIES ISOFORMS IN FIRST-DEGREE RELATIVES OF PATIENTS WITH RHEUMATOID ARTHRITIS IN A LATIN POPULATION

Abstracts Accepted for Publication, 2019
Background Rheumatoid arthritis (RA) affects approximately 1.5% of the population worldwide and 0.5-3.3% of the Mexican population1. Anti-carbamylated proteins (anti-CarP) antibodies are identified in RA patients with a prevalence up to 44%2, early ...
Hemin Lee, Yinzhu Jin, Jun Liu, Ezra Cohen, Sarah Chen, Seoyoung Kim   +5 more
semanticscholar   +1 more source

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes

Arthritis Research & Therapy, 2018
Background The autoantibody profile of seropositive rheumatoid arthritis (RA) is very diverse and consists of various isotypes and antibodies to multiple post-translational modifications. It is yet unknown whether this varying breadth of the autoantibody
Emma C. de Moel, Veerle F. A. M. Derksen, Gerrie Stoeken, Leendert A. Trouw, Holger Bang, Robbert J. Goekoop, Irene Speyer, Tom W. J. Huizinga, Cornelia F. Allaart, René E. M. Toes, Diane van der Woude   +10 more
doaj   +1 more source

Evaluation of anti-citrullinated and anti-carbamylated antibodies in mexicans with rheumatoid arthritis and at-risk individuals

Revista de Investigación Clínica
Background: Rheumatoid arthritis (RA) diagnosis is a challenge in the initial phases of the disease when clinical symptoms are only starting to develop.
Edgar E. Lara-Ramírez, Betzaida Cuevas-Córdoba, Diana Olguín-Calderon, Yadira Bastian, César Ramos-Remus, José D. Castillo-Ortiz, Martín Zapata-Zúñiga, Jesús Núñez-Contreras, Leendert A. Trouw, José A. Enciso-Moreno, Julio E. Castañeda-Delgado   +10 more
doaj   +1 more source

Anti-carbamylated protein antibodies in patients with ageing associated inflammatory chronic disorders [PDF]

Rheumatology, 2015
Marcos, López-Hoyos, Lorena, Álvarez-Rodríguez, Michael, Mahler, Silvia, Torices, Jaime, Calvo-Alén, Ignacio, Villa, Andrea, Seaman, Alvin, Yee, Victor, Martínez-Taboada   +8 more
openaire   +2 more sources

Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective ultrasound cohort study

RMD Open
Objectives To evaluate the potential of clinical factors, ultrasound findings, serum autoantibodies, and serum cytokine and chemokine profiles as predictors of clinical outcomes in rheumatoid arthritis (RA).Patients and methods We included 200 patients ...
Yukitaka Ueki, Tom W J Huizinga, René E M Toes, Shoichi Fukui, Tomoki Origuchi, Takahiro Maeda, Atsushi Kawakami, Tomohiro Koga, Naoki Matsuoka, Toshihiko Hidaka, Naoki Iwamoto, Mami Tamai, Shin-ya Kawashiri, Akitomo Okada, Ayako Nishino, Tamami Yoshitama, Takahisa Suzuki, Toshimasa Shimizu, Shimpei Morimoto, Tomomi Tsuru, Karin A J van Schie, Masahiro Ayano, Remi Sumiyoshi, Yushiro Endo, Tohru Michitsuji, Kaori Furukawa, Masataka Umeda, Nobutaka Eiraku, Hiroaki Hamada   +28 more
doaj   +1 more source

Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis

, 2017
Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA-adducts are part of the natural antibody pool, while elevated levels of IgG ...
Amara, Khaled, Catrina, Anca I., Engstrom, Marianne, Greenberg, Jeffrey D., Gronwall, Caroline, Hardt, Uta, Klareskog, Lars, Krishnamurthy, Akilan, Malmstrom, Vivianne, Scheel-Toellner, Dagmar, Silverman, Gregg J., Steen, Johanna, Sun, Meng, Ytterberg, A. Jimmy, Zubarev, Roman A.   +14 more
core   +1 more source

Carbamylated vimentin represents a relevant autoantigen in Latin American (Cuban) rheumatoid arthritis patients [PDF]

, 2016

core   +1 more source