Results 11 to 20 of about 809 (171)

Smoking as a risk factor for rheumatoid arthritis: predominant association with IgA autoantibodies - comprehensive analysis of anti-modified protein antibodies with smoking and genetic risk factors in rheumatoid arthritis. [PDF]

Arthritis Res Ther
BACKGROUND: Rheumatoid arthritis (RA) is an autoimmune disease characterized by the presence of autoantibodies against modified proteins, known as anti-modified protein autoantibodies (AMPAs).
van Wesemael TJ, Morton FR, Heutz JW, Maurits MP, Dorjée AL, Porter D, Huizinga TWJ, Raza K, Toes REM, Knevel R, de Jong PHP, Svärd A, van der Woude D.   +12 more
europepmc   +7 more sources

Rheumatoid arthritis – usage of biomarkers in disease’ prognosing, diagnosing and monitoring [PDF]

Quality in Sport
Introduction: Rheumatoid arthritis (RA) is a chronic inflammatory joint disease which has a significant, negative influence of patients’ quality of daily life. In routine clinical practice there is a usage of classic biomarkers, such as rheumatoid factor
Sabina Skrzynecka, Hanna Pietruszewska, Oliwia Sędziak, Natalia Kruszewska, Urszula Borucińska   +4 more
doaj   +3 more sources

Neutrophilic Activity Biomarkers (Plasma Neutrophil Extracellular Traps and Calprotectin) in Established Patients with Rheumatoid Arthritis Receiving Biological or JAK Inhibitors: A Clinical and Ultrasonographic Study [PDF]

Rheumatology and Therapy
Introduction This study assesses the accuracy of neutrophil activation markers, including neutrophil extracellular traps (NETs) and calprotectin, as biomarkers of disease activity in patients with established rheumatoid arthritis (RA).
Beatriz Frade-Sosa, Andrés Ponce, Estíbaliz Ruiz-Ortiz, Noemí De Moner, María J. Gómara, Ana Belén Azuaga, Juan C. Sarmiento-Monroy, Rosa Morlà, Virginia Ruiz-Esquide, Laura Macías, Nuria Sapena, Lola Tobalina, Julio Ramirez, Juan D. Cañete, Jordi Yague, Josep M. Auge, José A. Gomez-Puerta, Odette Viñas, Isabel Haro, Raimon Sanmarti   +19 more
doaj   +2 more sources

Evidence of Site-Specific Mucosal Autoantibody Secretion in Rheumatoid Arthritis. [PDF]

Arthritis Rheumatol
Objective Anti–citrullinated protein antibodies (ACPA) have been detected in sputum and saliva, indicating that anti–modified protein antibodies (AMPA) can be produced at mucosal sites in patients with rheumatoid arthritis (RA). However, the body's largest mucosal compartment, the gut, has not yet been examined.
Derksen VFAM, Martinsson K, van Mourik AG, Wagenaar CA, Toes REM, Walrabenstein W, Sjöberg D, van Schaardenburg D, Huizinga TWJ, Kastbom A, Svärd A, van der Woude D.   +11 more
europepmc   +2 more sources

Research progress on anti-carbamylated protein antibodies in connective tissue disease [PDF]

Xin yixue, 2023
Connective tissue disease （CTD） is a group of chronic autoimmune diseases characterized by pathological changes in systemic organs and multisystems. The diagnosis of CTD mainly depends on clinical manifestations and specific autoantibodies.
Dong Rongrong, Yang Qingrui, Ma Zhenzhen
doaj   +1 more source

Commentary: Commentary: Antibodies against multiple post-translationally modified proteins aid in diagnosis of autoimmune hepatitis and associate with complete biochemical response to treatment. [PDF]

Front Med (Lausanne), 2023
van den Beukel MD, Stoelinga AEC, van der Meer AJ, van der Meulen S, Zhang L, Tushuizen ME, van Hoek B, Trouw LA.   +7 more
europepmc   +4 more sources

Rheumatoid arthritis and the proinflammatory cytokine IL-17 [PDF]

Folia Medica, 2023
Introduction: Rheumatoid arthritis (RA) is the most common inflammatory joint disease. Various proinflammatory cytokines are involved in the pathogenesis of this chronic disorder.
Pavel Selimov, Rositsa Karalilova, Ljubinka Damjanovska, Ginka Delcheva, Teodora Stankova, Katya Stefanova, Ana Maneva, Teodor Selimov, Anastas Batalov   +8 more
doaj   +3 more sources

Anti-Carbamylated Fibrinogen Antibodies Might Be Associated With a Specific Rheumatoid Phenotype and Include a Subset Recognizing In Vivo Epitopes of Its γ Chain One of Which Is Not Cross Reactive With Anti-Citrullinated Protein Antibodies

Frontiers in Immunology, 2021
To identify the targets recognized by anti-carbamylated protein antibodies (anti-CarP) in patients with early Rheumatoid Arthritis (RA), to study the cross-reactivity between anti-CarP and anti-citrullinated protein antibodies (ACPA) and to evaluate ...
Pauline Brevet, Pauline Brevet, Claire Lattard, Claire Lattard, Clément Guillou, Pascal Rottenberg, Patrice Fardellone, Xavier Le-Loët, Thierry Lequerré, Thierry Lequerré, Pascal Cosette, Olivier Boyer, Olivier Boyer, Manuel Fréret, Manuel Fréret, Olivier Vittecoq, Olivier Vittecoq   +16 more
doaj   +1 more source

Detection and clinical significance of anti-carbamylated protein antibody in serologically negative patients with rheumatoid arthritis [PDF]

Xin yixue, 2022
Objective To probe into the level and clinical significance of anti-carbamylated protein （CarP） antibody in serologically negative patients with rheumatoid arthritis （RA）.
Wu Tao, Chen Chutao, Yang Lijuan, Zou Yaowei, Ma Jianda, Xu Yanhui, Jia Lei, Dai Lie
doaj   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered 'early'? [PDF]

Eur J Clin Invest
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Hysa E, Gotelli E, Pizzorni C, Paolino S, Sulli A, Smith V, Campitiello R, Cutolo M.   +7 more
europepmc   +2 more sources