Results 31 to 40 of about 11,963 (190)

Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases [PDF]

, 2016
Antibodies against carbamylated proteins (anti-CarP) have been recently identified in the sera of patients with rheumatoid arthritis (RA). The objective of the study was to evaluate the prevalence, sensitivity and specificity of anti-CarP compared to ...
Alessandri, Cristiano, Barbati, Cristiana, Ceccarelli, Fulvia, Colasanti, Tania, Conti, Fabrizio, DI FRANCO, Manuela, Mancini, Riccardo, Morello, Francesca, Pecani, Arbi, Pendolino, Monica, Priori, Roberta, Riccieri, Valeria, Sabatinelli, Danilo, Spinelli, FRANCESCA ROMANA, Truglia, Simona, Valesini, Guido, Vomero, Marta   +16 more
core   +1 more source

Anti-carbamylated protein autoantibodies associated with mortality in Spanish rheumatoid arthritis patients. [PDF]

PLoS ONE, 2017
Patients with rheumatoid arthritis (RA) have an increased mortality rate that is associated with the presence of RA-specific autoantibodies in many studies.
Laura Vidal-Bralo, Eva Perez-Pampin, Cristina Regueiro, Ariana Montes, Rosana Varela, Maria Dolores Boveda, Juan J Gomez-Reino, Antonio Gonzalez   +7 more
doaj   +1 more source

OP0178 Antibodies against Carbamylated Proteins (ANTI-CARP), A New Type of Autoantibody, in Spanish Patients with Rheumatoid Arthritis [PDF]

Annals of the Rheumatic Diseases, 2014
Background Antibodies against carbamylated proteins (anti-CarP) are a new type of autoantibodies present in sera of patients with rheumatoid arthritis (RA). These antibodies, measured as the reactivity against carmabylated proteins from Fetal Calf Serum (FCS), do not show cross-reactivity with anti-CCP antibodies, and are associated with radiologic ...
A. Montes, E. Perez-Pampín, M.D. Bόveda, J.J. Gόmez-Reino, A. González   +4 more
openaire   +6 more sources

A5.4 Anti Carbamylated Protein Antibodies (Anti-CarP) Are Present in Arthralgia Patients and Predict the Development of Rheumatoid Arthritis [PDF]

Annals of the Rheumatic Diseases, 2013
Background/Objective Recently, we discovered a new auto- antibody system in rheumatoid arthritis (RA): anti carbamylated protein antibodies (anti-CarP). These antibodies have additional prognostic value in predicting joint destruction when compared to anti-citrullinated protein antibodies (ACPA).
Jing Shi, Lotte A van de Stadt, EW Nivine Levarht, Tom WJ Huizinga, René EM Toes, Leendert A Trouw, Dirkjan van Schaardenburg   +6 more
openaire   +1 more source

Localization of α-synuclein in teleost central nervous system: immunohistochemical and Western blot evidence by 3D5 monoclonal antibody in the common carp, Cyprinus carpio [PDF]

, 2015
Alpha synuclein (α-syn) is a 140 amino acid vertebrate-specific protein, highly expressed in the human nervous system and abnormally accumulated in Parkinson's disease and other neurodegenerative disorders, known as synucleinopathies.
CASINI, Arianna, CIONI, Carla, L. D’Este, S. Yu, TONI, MATTIA, VACCARO, Rosa, VIVACQUA, GIORGIO   +6 more
core   +1 more source

AB1170 Prevalence of anti-carp antibodies in patients with primary sjÖgren's syndrome: association with clinical, serological and histological aspects [PDF]

Annals of the Rheumatic Diseases, 2017
Background The presence of antibodies against carbamylated peptides (anti-CarP) has been associated with increased disease activity and severe joint damage in rheumatoid arthritis. Our group has demonstrated their presence also in other inflammatory conditions with a high prevalence in Sjogren9s Syndrome (SS) (14/45, 31.1%)1.
S Colafrancesco, G Piacarelli, A Pecani, T Colasanti, F Spinelli, C Alessandri, C Barbati, M Vomero, B Cerbelli, R Priori, G Valesini   +10 more
openaire   +1 more source

Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy

BMC Musculoskeletal Disorders, 2021
Background Blocking of the Tumor Necrosis Factor (TNF) activity is a successful therapeutic approach for 50–60% of rheumatoid arthritis (RA) patients. However, there are yet no biomarkers to stratify patients for anti-TNF therapy.
Antonio Julià, María López-Lasanta, Francisco Blanco, Antonio Gómez, Isabel Haro, Antonio Juan Mas, Alba Erra, Ma Luz García Vivar, Jordi Monfort, Simón Sánchez-Fernández, Isidoro González, Mercedes Alperi, Raúl Castellanos-Moreira, Antonio Fernández-Nebro, César Díaz-Torné, Núria Palau, Raquel Lastra, Jordi Lladós, Raimon Sanmartí, Sara Marsal   +19 more
doaj   +1 more source

A glycosylphosphatidylinositol-anchored carbonic anhydrase-related protein of Toxoplasma gondii is important for rhoptry biogenesis and virulence [PDF]

, 2017
Carbonic anhydrase-related proteins (CARPs) have previously been described as catalytically inactive proteins closely related to α-carbonic anhydrases (α-CAs).
Beejan Asady, Isabelle Coppens, Jessica C. Kissinger, Leandro Lemgruber, Nathan M. Chasen, Rossiane C. Vommaro, Silvia N. J. Moreno, William J. Sullivan   +7 more
core   +2 more sources

Identification of an essential virulence gene of cyprinid herpesvirus 3 [PDF]

, 2017
The genus Cyprinivirus consists of a growing list of phylogenetically related viruses, some of which cause severe economic losses to the aquaculture industry. The archetypal member, cyprinid herpesvirus 3 (CyHV-3) causes mass mortalities worldwide in koi
Boutier, Maxime, Davison, Andrew J., Gao, Yuan, Suárez, Nicolás, Vancsok, Catherine, Vanderplasschen, Alain   +5 more
core   +2 more sources

Anticarbamylated protein (anti-CarP) antibodies are present in sera of juvenile idiopathic arthritis (JIA) patients

Annals of the Rheumatic Diseases, 2013
In juvenile idiopathic arthritis (JIA) patients there is a lack of markers that predict severe disease. Although anticitrullinated protein antibodies (ACPA) have contributed substantially to the understanding of rheumatoid arthritis (RA),1 their detection in JIA has not been equally useful as incidence rates in JIA patients are low2 and merely confined
Muller, P.C.E.H., Anink, J., Shi, J., Levarht, E.W.N., Reinards, T.H.C.M., Otten, M.H., Tol, M.J.D. van, Jol-van der Zijde, C.M., Brinkman, D.M.C., Allaart, C.F., Hoppenreijs, E.P., Koopman-Keemink, Y., Kamphuis, S.S.M., Dolman, K., Berg, J.M. van den, Rossum, M.A.J. van, Suijlekom-Smit, L.W.A. van, Schilham, M.W., Huizinga, T.W.J., Toes, R.E.M., Cate, R. ten, Trouw, L.A.   +21 more
openaire   +4 more sources