Results 61 to 70 of about 11,963 (190)

Are rheumatoid factor, anti-citrullinated, and anti-carbamylated protein antibodies linked by post-translational modification of IgG? [PDF]

, 2016
This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.Accepted manuscript online: 2 August 2016No abstract is available.Support for this project was provided by the Cornwall Arthritis ...
Abedi-Valugerdi, Aho, Brink, Clavarino, Jin, Koppejan, Koro, Ling, Lugli, Rangel-Moreno, Tarcsa, Wang   +11 more
core   +1 more source

CRISPR‐Enhanced RAA‐SHERLOCK Assay for Point‐of‐Care Detection of Cyprinid Herpesvirus‐3: Development, Validation and Clinical Application

Journal of Fish Diseases, EarlyView.
ABSTRACT Koi herpesvirus disease (KHVD), caused by Cyprinid herpesvirus‐3 (CyHV‐3), poses a significant threat to global aquaculture due to its high mortality rates and economic impact. Current diagnostic methods, such as PCR, are limited by equipment dependency and procedural complexity, hindering point‐of‐care (POC) applications.
Hatem Soliman, Naveed Akram, Mona Saleh
wiley   +1 more source

Herpesvirus Infection Induces both Specific and Heterologous Antiviral Antibodies in Carp

Frontiers in Immunology, 2018
IgM antibody diversity induced by viral infection in teleost fish sera remains largely unexplored despite several studies performed on their transcript counterparts in lymphoid organs.
Julio M. Coll
doaj   +1 more source

Geo-epidemiology of autoantibodies in rheumatoid arthritis: comparison between four ethnically diverse populations

Arthritis Research & Therapy, 2023
Background Rheumatoid arthritis (RA) occurs across the globe in different ethnic populations. Most RA patients harbor anti-modified protein antibodies (AMPA); however, it is unclear whether differences exist in autoantibody responses at different ...
Emma C. de Moel, Leendert A. Trouw, Chikashi Terao, Nimmisha Govind, Mohammed Tikly, Hani El-Gabalawy, Irene Smolik, Holger Bang, Tom W. J. Huizinga, René E. M. Toes, Diane van der Woude   +10 more
doaj   +1 more source

Određivanj prisutnosti ekotoksikološki važnih Pgp i MRP-proteina u šarankama na genskoj i proteinskoj razini [PDF]

, 2010
One of the most intriguing defence strategies which aquatic organisms developed through evolution is multixenobiotic resistance (MXR). The key mediators of MXR activity are ATP-binding cassette (ABC) transport proteins. They provide resistance of aquatic
Anamarija Brozović, Damjan Franjević, Roberta Sauerborn Klobučar, Roko Žaja, Tvrtko Smital   +4 more
core   +2 more sources

Engineering Marker‐Free Lettuce Chloroplast Genome to Express Functional Glucagon‐Like Peptide‐1 Receptor Agonists Exenatide and Lixisenatide

Plant Biotechnology Journal, EarlyView.
Engineering of marker‐free lettuce chloroplast genome to express CTB‐Exenatide and CTB‐Lixisenatide for oral delivery. Upper panel: Chemically synthesised exenatide or lixisenatide require expensive production, purification, refrigeration and invasive delivery methods.
Rahul Singh, Henry Daniell
wiley   +1 more source

Homeostatic Functions of Tecrem, a CD46-Like Regulatory Protein of Complement Activation, on Epithelial Cells in Carp Fish

Journal of Marine Science and Engineering, 2021
Fish mucosal surface is a significant interface for pathogens to infect from an aqueous environment. In addition to mucosal innate and adaptive immune factors, epithelial cells are considered as a significant physical barrier against microbial invasion ...
Harsha Prakash, Shiori Motobe, Takahiro Nagasawa, Tomonori Somamoto, Miki Nakao   +4 more
doaj   +1 more source

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

Periodontology 2000, EarlyView.
Abstract Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to manage patients with both periodontitis and RA. This review seeks to provide an update on interventional and mechanistic investigations, including a brief summary of European Research programs investigating the link between periodontitis and RA. Recent
Isabel Lopez‐Oliva, Jennifer Malcolm, Shauna Culshaw   +2 more
wiley   +1 more source

Evolution of anti-modified protein antibody responses can be driven by consecutive exposure to different post-translational modifications

Arthritis Research & Therapy, 2021
Background Besides anti-citrullinated protein antibodies (ACPA), rheumatoid arthritis patients (RA) often display autoantibody reactivities against other post-translationally modified (PTM) proteins, more specifically carbamylated and acetylated proteins.
M. Volkov, A. S. B. Kampstra, K. A. van Schie, A. Kawakami, M. Tamai, S. Kawashiri, T. Maeda, T. W. J. Huizinga, R. E. M. Toes, D. van der Woude   +9 more
doaj   +1 more source

Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. [PDF]

, 2014
Ewing sarcoma is the second-most-common bone cancer in children. Driven by an oncogenic chromosomal translocation that results in the expression of an aberrant transcription factor, EWS/FLI, the disease is typically aggressive and micrometastatic upon ...
Beckerle, Mary C, Chaturvedi, Aashi, Grossmann, Allie H, Hoffman, Laura M, Jensen, Christopher C, Lessnick, Stephen L, Lin, Yi-Chun, Randall, R Lor, Welm, Alana L   +8 more
core   +1 more source