Results 71 to 80 of about 11,963 (190)

Fertility and Early Embryonic Development Toxicity of hzVSF‐v13 in Sprague–Dawley Rats

Journal of Applied Toxicology, Volume 46, Issue 2, Page 560-568, February 2026.
ABSTRACT Humanized virus suppressing factor–variant 13 (hzVSF‐v13), a monoclonal IgG4 antibody, is a potential therapeutic candidate for COVID‐19. Although fertility and embryonic developmental toxicity studies are crucial for the safety evaluation of new drugs, the toxicological profile of hzVSF‐v13 remains unexplored.
Ji‐Seong Jeong, Sang‐Yun Kim, Jinsoo Lee, Seung‐Jin Lee, Onju Ham, Woojin Kim, Wan‐Jung Im, Sungman Park, Kyong‐Cheol Ko, Jong‐Choon Kim, Yong‐Bum Kim   +10 more
wiley   +1 more source

Calsequestrins in skeletal and cardiac muscle from adult Danio rerio [PDF]

, 2015
Calsequestrin (Casq) is a high capacity, low affinity Ca2+-binding protein, critical for Ca2+-buffering in cardiac and skeletal muscle sarcoplasmic reticulum. All vertebrates have multiple genes encoding for different Casq isoforms.
Argenton, Francesco, Furlan, Sandra, Mosole, Simone, Murgia, Marta, Nagaraj, Nagarjuna, Nori, Alessandra, Volpe, Pompeo   +6 more
core   +1 more source

An investigation of acute effects at various doses of malathion on glucose homeostasis and insulin resistance in rat liver, pancreas and serum [PDF]

, 2020
Objective. This study investigates acute effects of various doses of Malathion on glucose homeostasis and insulin resistance in rat. Methods. Rats were randomly divided into four groups of 6 animals each. Corn oil was given orally to Group 1.
Ekremoğlu, Murat, Pasaoğlu, Hatice, Pasaoğlu, Özge Tuğce, Severcan, Çınar, Şen, Bayram   +4 more
core   +3 more sources

Frequency of consumption of different fish, crustacean and mollusc species contributing to methylmercury exposure and consumer awareness of national advice on their consumption

EFSA Journal, Volume 24, Issue 2, February 2026.
Abstract Following a request of the European Commission, EFSA assessed fish and other seafood consumption patterns and consumer awareness of related health risks and benefits across the 27 Member States, Iceland and Norway. Awareness of existence of consumption national advice and to which extent this advice influence consumers consumption behaviour ...
European Food Safety Authority (EFSA), Angela Bearth, Tom Jansen, Mario Mazzocchi, Wim Verbeke, Georgios Alaveras, Adamantia Kanellakopoulou, Nikolaos Koffas, Androniki Naska, Krystalia Niforou, Anthony I. M. Smith, Joana Isabel Sousa Lourenco, Giorgia Zamariola, Sofia Ioannidou   +13 more
wiley   +1 more source

Improved diagnosis of rheumatoid arthritis using an artificial neural network

Scientific Reports, 2022
Rheumatoid arthritis (RA) is chronic systemic disease that can cause joint damage, disability and destructive polyarthritis. Current diagnosis of RA is based on a combination of clinical and laboratory features.
Linlu Bai, Yuan Zhang, Pan Wang, Xiaojun Zhu, Jing-Wei Xiong, Liyan Cui   +5 more
doaj   +1 more source

Anti-Carbamylated LL37 Antibodies Promote Pathogenic Bone Resorption in Rheumatoid Arthritis

Frontiers in Immunology, 2021
ObjectiveAntibodies against carbamylated proteins (anti-CarP) are associated with poor prognosis and the development of bone erosions in rheumatoid arthritis (RA).
Liam J. O’Neil, Christopher B. Oliveira, Donavon Sandoval-Heglund, Ana Barrera-Vargas, Javier Merayo-Chalico, Eduardo Aguirre-Aguilar, Mariana J. Kaplan, Carmelo Carmona-Rivera   +7 more
doaj   +1 more source

Integrated Use of Oxidative Stress and Histological Biomarkers of T. tinca as Indicators of 17‐Alpha‐Ethynylestradiol Exposure

Environmental Toxicology, Volume 41, Issue 1, Page 49-67, January 2026.
ABSTRACT The potential adverse effects of 17‐alpha‐ethynylestradiol (50, 100, and 500 μg EE2/kg b.w., for 30 days) on tench ( Tinca tinca ) were evaluated by integrating biomarkers including physiological (hepato‐somatic index, spleen‐somatic index, and hematocrit), oxidative stress (catalase, glutathione peroxidase, and glutathione reductase ...
Ana L. Oropesa, Alfonso Ramos, Cesar Fallola, Luis J. Gomez   +3 more
wiley   +1 more source

Integration of Colorimetric Sensing Dyes and Multi‐Substrate Arrays for Food Quality and Safety Monitoring: Design, Optimization, and Analysis

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 1, January 2026.
ABSTRACT As food safety issues gain increasing attention, the need for rapid, accurate, and low‐cost detection techniques becomes essential. Colorimetric sensors, known for their rapid response, high sensitivity, low cost, and readily observable results, are playing an increasingly important role in food quality inspection. This review article provides
Jingfei Shen, Qisheng Liu, Ruxin Zhang, Zhengzhu Zhang, Quansheng Chen, Jingming Ning, Luqing Li   +6 more
wiley   +1 more source

Proteomic and functional analyses of the virion transmembrane proteome of cyprinid herpesvirus 3 [PDF]

, 2017
Virion transmembrane proteins (VTPs) mediate key functions in the herpesvirus infectious cycle. Cyprinid herpesvirus 3 (CyHV-3) is the archetype of fish alloherpesviruses. The present study was devoted to CyHV-3 VTPs.
Boutier, Maxime, Davison, Andrew J., Gao, Yuan, Gillet, Laurent, Joanna, Jazowiecka-Rakus, Leroy, Baptiste, Peñaranda, Ma. Michelle D., Raj, V. Stalin, Suarez, Nicolás M., Vancsok, Catherine, Vanderplasschen, Alain F.C., Wattiez, Ruddy, Wilke, Gavin S.   +12 more
core   +1 more source

A matter arising: When should inflammatory and autoimmune rheumatic diseases be considered ‘early’?

European Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
Timely recognition of inflammatory and autoimmune rheumatic diseases (IARDs) is important to optimize the early diagnosis with tailored interventions and possible prevention of irreversible organ damage. This narrative review provides an update by summarizing the advances in identifying the early stages of rheumatoid arthritis, systemic sclerosis and ...
Elvis Hysa, Emanuele Gotelli, Carmen Pizzorni, Sabrina Paolino, Alberto Sulli, Vanessa Smith, Rosanna Campitiello, Maurizio Cutolo   +7 more
wiley   +1 more source