Immunosuppression with Rituximab in Glomerular Diseases in Adults: Who, How and When?
Rituximab, a monoclonal antibody with the ability to bind itself to CD20, leads to a rapid depletion of B-cells (in around 24-72 hours), limiting antibody formation.
Raquel Pereira Sousa Pinto +8 more
doaj +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
CAQ Corner: Immune‐mediated complications
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley +1 more source
Human monoclonal antibody combination against SARS coronavirus : synergy and coverage of escape mutants [PDF]
Background: Experimental animal data show that protection against severe acute respiratory syndrome coronavirus (SARS-CoV) infection with human monoclonal antibodies (mAbs) is feasible.
Peiris, Joseph S. M. +73 more
core +1 more source
Evolution of anti- CD20 monoclonal antibody therapeutics in oncology [PDF]
Approval of an anti-CD20 chimeric monoclonal antibody, rituximab, has revolutionized cancer treatment and also validated CD20 targeting for providing benefit and improvement of overall response rate in B cell malignancies. Although many patients have benefited from the treatment of rituximab, there are still significant numbers of patients who are ...
Ezogelin, Oflazoglu, Laurent P, Audoly
openaire +2 more sources
Adaptive immunity in cancer immunology and therapeutics. [PDF]
Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution,
Spurrell, EL, Lockley, M
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Obinutuzumab, a new anti-CD20 antibody, and chlorambucil are active and effective in anti-MAG antibody polyneuropathy [PDF]
Rituximab, a chimeric anti-CD20 monoclonal antibody (mAb), has been used in polyneuropathy associated with anti-MAG antibody polyneuropathy with controversial results.
Livio Trentin +4 more
core +1 more source
Llama-Derived Single Domain Antibodies to Build Multivalent, Superpotent and Broadened Neutralizing Anti-Viral Molecules [PDF]
For efficient prevention of viral infections and cross protection, simultaneous targeting of multiple viral epitopes is a powerful strategy. Llama heavy chain antibody fragments (VHH) against the trimeric envelope proteins of Respiratory Syncytial Virus (
Schepens, B +94 more
core +1 more source
One mechanism by which monoclonal antibodies (mAb) help treat cancer or autoimmune disease is through triggering antibody-dependent cellular cytotoxicity (ADCC) via CD16 on Natural Killer (NK) cells.
Alexandros Karampatzakis +8 more
doaj +1 more source
Chronic lymphocytic leukaemia: Up-dated recommendations on diagnosis and treatment [PDF]
Diagnosis and treatment of chronic lymphatic leukaemia (CLL) are currently undergoing great change. New knowledge of prognosis factors and the numerous new therapeutic procedures now available, such as purine analogues, high-dose treatment and monoclonal
Hallek, M., Emmerich, B., Bergmann, M.
core +1 more source

