Prevalence of Rheumatoid Factor and Anti-citrullinated Protein Antibodies in Patients With Post-treatment Lyme Disease. [PDF]
Miller JB, Rebman A, Yang T, Aucott J.
europepmc +1 more source
Macrophage-centred crosstalk with infiltrating immune cells in rheumatoid arthritis and its regulation by mesenchymal stem cells. [PDF]
Zheng S +7 more
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Identification of individuals at high risk of developing rheumatoid arthritis: a balanced random forest model in a cohort of 1544 first-degree relatives. [PDF]
Aymon R +20 more
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Integrative multi-omic profiling in blood reveals distinct immune and metabolic signatures between ACPA-negative and ACPA-positive rheumatoid arthritis. [PDF]
Hur B +9 more
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Circulating secretory component-containing anti-citrullinated protein antibodies prior to symptom onset in rheumatoid arthritis. [PDF]
Martinsson K +3 more
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Cigarette Smoking: A Modifiable Environmental Factor in the Pathogenesis of Rheumatoid Arthritis. [PDF]
Masuko K.
europepmc +1 more source
Related searches:
Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis
Modern Rheumatology, 2011Autoantibodies with the highest specificity for rheumatoid arthritis (RA) are the antibodies directed to citrulline-containing epitopes, so-called anti-citrullinated peptide/protein antibodies (ACPA). During the past decade it became clear that the presence of these antibodies was highly predictive of and specific for RA, and illustrating the ...
Suwannalai, P. +3 more
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Fingerprinting of anti-citrullinated protein antibodies (ACPA): specificity, isotypes and subclasses
Lupus, 2015Anti-citrullinated protein antibodies (ACPA) are a family of rheumatoid arthritis (RA)-specific autoantibodies that recognize the amino acid citrulline, resulting from the post-translational modification of arginine. Peptidyl arginine deiminase, the enzyme responsible for citrullination, is present in humans in different isoforms with different tissue
PRATESI, FEDERICO +9 more
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Anti-citrullinated protein/peptide antibodies (ACPA) are highly specific and sensitive markers for rheumatoid arthritis (RA). For instance, for the anti-CCP2 assay, sensitivities ranging from 55% to 80% and specificities ranging from 90% to 98% have been reported.
B, Vander Cruyssen +6 more
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Background Susceptibility genes for anti-citrullinated peptide/protein antibodies (ACPA)-positive rheumatoid arthritis (RA) have been successfully discovered by the development of genome-wide association studies (GWAS). However, little is known about the genetic background of ACPA-negative RA.
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