Results 181 to 190 of about 8,957 (228)

Identification of individuals at high risk of developing rheumatoid arthritis: a balanced random forest model in a cohort of 1544 first-degree relatives. [PDF]

open access: yesRMD Open
Aymon R   +20 more
europepmc   +1 more source

Integrative multi-omic profiling in blood reveals distinct immune and metabolic signatures between ACPA-negative and ACPA-positive rheumatoid arthritis. [PDF]

open access: yesFront Immunol
Hur B   +9 more
europepmc   +1 more source

Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis

Modern Rheumatology, 2011
Autoantibodies with the highest specificity for rheumatoid arthritis (RA) are the antibodies directed to citrulline-containing epitopes, so-called anti-citrullinated peptide/protein antibodies (ACPA). During the past decade it became clear that the presence of these antibodies was highly predictive of and specific for RA, and illustrating the ...
Suwannalai, P.   +3 more
openaire   +4 more sources

Fingerprinting of anti-citrullinated protein antibodies (ACPA): specificity, isotypes and subclasses

Lupus, 2015
Anti-citrullinated protein antibodies (ACPA) are a family of rheumatoid arthritis (RA)-specific autoantibodies that recognize the amino acid citrulline, resulting from the post-translational modification of arginine. Peptidyl arginine deiminase, the enzyme responsible for citrullination, is present in humans in different isoforms with different tissue
PRATESI, FEDERICO   +9 more
openaire   +2 more sources

Anti-citrullinated protein/peptide antibodies (ACPA) in rheumatoid arthritis: Specificity and relation with rheumatoid factor

Autoimmunity Reviews, 2005
Anti-citrullinated protein/peptide antibodies (ACPA) are highly specific and sensitive markers for rheumatoid arthritis (RA). For instance, for the anti-CCP2 assay, sensitivities ranging from 55% to 80% and specificities ranging from 90% to 98% have been reported.
B, Vander Cruyssen   +6 more
openaire   +2 more sources

THU0462 Anti-Citrullinated Peptide/Protein Antibody (ACPA)-Negative RA Shares Large Proportion of Susceptibility Genes with Acpa-Positive RA

Annals of the Rheumatic Diseases, 2014
Background Susceptibility genes for anti-citrullinated peptide/protein antibodies (ACPA)-positive rheumatoid arthritis (RA) have been successfully discovered by the development of genome-wide association studies (GWAS). However, little is known about the genetic background of ACPA-negative RA.
C. Terao   +17 more
openaire   +1 more source

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