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OP0268 Anti-Citrullinated Protein Antibody (ACPA) Status in the General Population and as a Predictor of Future Inflammatory Polyarthritis: The EPIC-2-Noar Study

Annals of the Rheumatic Diseases, 2015
Background Anti-citrullinated protein antibody (ACPA) immune response occurs several years prior to the diagnosis of rheumatoid arthritis (RA). However, limited data are available on ACPA status in the general population compared to those who develop RA or inflammatory polyarthritis (IP) in the future. Objectives The aim of this study was to examine
S.M. Verstappen   +9 more
openaire   +1 more source

AB0227 Anti Citrullinated Protein Antibody (ACPA) in Relation to Serum Receptor Activator of Nuclear Factor Kappa-B Ligand (RANKL) and Disease Activity in Rheumatoid Arthritis

Annals of the Rheumatic Diseases, 2015
Background Bone destruction in rheumatoid arthritis (RA) remains a main concern in the clinical practice where the destructed joints may lead to impaired normal functional activity of patients. Antibodies against citrullinated proteins (ACPA) and high levels of Receptor activator of nuclear factor kappa-B ligand (RANKL) have been linked to altered ...
A.F. Elbelasy   +3 more
openaire   +1 more source

FRI0111 Unexpected finding of anti-citrullinated protein antibodies (ACPA) in cerebrospinal fluid of RA patients with intact blood brain barrier - potential for autoimmune reactions in the CNS

Annals of the Rheumatic Diseases, 2012
Background Arthritis is known to associate with upregulation of inflammatory mediators in the central nervous system (CNS) as shown in earlier experimental studies (1). However, little is known about the possible presence of intrathecal immune activation in RA patients, which may have importance for cerebral symptoms, such as fatigue.
E. Le Maitre   +5 more
openaire   +1 more source

POS0351 NEITHER ANTI-CITRULLINATED PROTEIN ANTIBODIES (ACPA) NOR POLYCLONAL IgG ARE ASSOCIATED WITH BONE MASS, IN ELDERLY MEN

Annals of the Rheumatic Diseases, 2022
M. Nurkkala   +5 more
openaire   +1 more source

The contemporary management of cancers of the sinonasal tract in adults

Ca-A Cancer Journal for Clinicians, 2023
Rajat Thawani
exaly  

Highly accurate protein structure prediction with AlphaFold

Nature, 2021
John M Jumper   +2 more
exaly  

POS1039 ANTI-CITRULLINATED PROTEIN ANTIBODY (ACPA) REACTIVITY TOWARDS NEUTROPHIL-DERIVED ANTIGENS: THE IMPACT OF CLONAL DIVERSITY AND INTER-INDIVIDUAL VARIATION

Scientific Abstracts, 2023
A. Cîrciumaru   +15 more
openaire   +1 more source

The protein corona from nanomedicine to environmental science

Nature Reviews Materials, 2023
Assist Prof Morteza Mahmoudi   +2 more
exaly  

Human anti-citrullinated protein antibodies (ACPA) not only activate the classical- but also the alternative complement pathway

Molecular Immunology, 2009
L.A. Trouw   +7 more
openaire   +1 more source

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