GENO PROTECTIVE AND ANTI-APOPTOTIC EFFECT OF GREEN TEA AGAINST PERINATAL LIPOPOLYSACCHARIDE-EXPOSURE INDUCED LIVER TOXICITY IN RAT NEWBORNS [PDF]
, 2017 published_or_final_versio
Ajarem, J +5 more
core +3 more sources
Effect of Pheretima aspergillum on reducing fibrosis: A systematic review and meta-analysis
Frontiers in Pharmacology, 2022 Background:Pheretima aspergillum (common name: Earthworm, Chinese name: dilong) has been used in traditional Chinese medicine for thousands of years. Recently, a few scientific studies have investigated the antifibrotic effects of Dilong extract (DE) and
Tianren Xu +8 more
doaj +1 more source
Semi-individualised Chinese medicine treatment as an adjuvant management for diabetic nephropathy: a pilot add-on, randomised, controlled, multicentre, open-label pragmatic clinical trial [PDF]
, 2016 published_or_final_versio
Chan, GCW +14 more
core +1 more source
New strategy of drug repositioning through anti‐fibrosis characteristic
The FASEB Journal, 2019 Background Fibrosis is a common pathogenesis in most diseases, thus different diseases may share targets and drugs related to fibrosis. For a drug that targets fibrotic process, it is likely an effective drug for treating diseases other than its original purpose. Therefore, the current study aimed to investigate
Xiaoyi Li +6 more
openaire +1 more source
Mesoscale nanoparticles encapsulated with emodin for targeting antifibrosis in animal models
Open Chemistry, 2020 The aim of this study is to explore the kidney-targeting capability of mesoscale nanoparticles (MNPs)-emodin (Em-MNPs) and its potential antifibrosis in the animal model.
Tan Lishan +6 more
doaj +1 more source
Treatment of myocardial interstitial fibrosis in pathological myocardial hypertrophy
Frontiers in Pharmacology, 2022 Pathological myocardial hypertrophy can be caused by a variety of diseases, mainly accompanied by myocardial interstitial fibrosis (MIF), which is a diffuse and patchy process, appearing as a combination of interstitial micro-scars and perivascular ...
Fuyu Zhu +3 more
doaj +1 more source
Activin–like kinase–3 activity is important for kidney regeneration and reversal of fibrosis [PDF]
, 2014 Molecules associated with TGF-β superfamily such as BMPs and TGF-β are key regulators of inflammation, apoptosis and cellular transitions. Here, we demonstrate that the BMP receptor activin–like kinase 3 (Alk3) is elevated early in response to kidney ...
Basukonda, Dattatreyamurty +14 more
core +1 more source
Drugs Targeting the A3 Adenosine Receptor: Human Clinical Study Data
Molecules, 2022 The A3 adenosine receptor (A3AR) is overexpressed in pathological human cells. Piclidenoson and namodenoson are A3AR agonists with high affinity and selectivity to A3AR.
Pnina Fishman
doaj +1 more source
Mesenchymal stem cell response to topographically modified CoCrMo [PDF]
, 2015 Surface roughness on implant materials has been shown to be highly influential on the behavior of osteogenic cells. Four surface topographies were engineered on cobalt chromium molybdenum (CoCrMo) in order to examine this influence on human mesenchymal ...
Bozec, L, Brett, P, Logan, N, Traynor, A
core +1 more source
Artificial Cells, Nanomedicine, and Biotechnology, 2023 Tumour development is not only an independent event of genetic mutation and overgrowth of tumour cells but is the result of a synergistic interaction between a malignant tumour and its surrounding tumour stromal microenvironment.
Chunjing Guo +8 more
doaj +1 more source