Anti-GBM disease with positive serum anti-GBM antibodies but negative IgG deposition: A case report [PDF]
SAGE Open Medical Case Reports, 2023 Anti-glomerular basement membrane antibodies are significantly specific for detecting anti-glomerular basement membrane disease. These antibodies are typically targeted against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen and,
Kimia Kazemzadeh +3 more
doaj +5 more sources
Comparison of the performance of a chemiluminescence assay and an ELISA for detection of anti-GBM antibodies [PDF]
Renal Failure, 2020 Objective Autoantibodies to the α3 chain noncollagen 1 domain of type IV collagen (α3(IV)NC1) are a serological hallmark in the diagnosis of anti-glomerular basement membrane (GBM) disease.
Ying Tan +3 more
doaj +6 more sources
Crescentic glomerulonephritis with anti-GBM antibody but no glomerular deposition [PDF]
BMC Nephrology, 2018 Background Anti-glomerular basement membrane (GBM) antibodies are highly specific for Goodpasture’s or anti-GBM disease, in which they are generally directed against the non-collagenous (NC1) domain of the alpha 3 chain of type IV collagen(α3(IV)), and ...
Omid Sadeghi-Alavijeh +5 more
doaj +5 more sources
Crescentic Glomerulonephritis with Anti-GBM and p-ANCA Antibodies [PDF]
Case Reports in Nephrology, 2012 We are presenting a case of renal failure with anti-GBM and p-ANCA antibodies positive. Patients with dual antibodies are considered to be a vasculitis-variant of anti-GBM antibody nephritis. These patients may have atypical presentation and it may delay
Tariq Javed, Parag Vohra
doaj +4 more sources
An unusual presentation of propylthiouracil-induced anti-MPO and PR3 positive ANCA vasculitis with associated anti-GBM antibodies, IgA nephropathy and an IgG4 interstitial infiltrate: a case report [PDF]
BMC Nephrology, 2020 Background A number of disease processes can culminate in rapidly progressive glomerulonephritis, including pauci-immune focal segmental necrotising glomerulonephritis, usually seen with positive serum antineutrophil cytoplasmic antibodies (ANCA ...
J. R. Galante +5 more
doaj +2 more sources
Frontiers in Immunology, 2020 IntroductionAnti-glomerular basement membrane (GBM) antibodies are pathogenic antibodies first detected in renal-limited anti-GBM disease and in Goodpasture disease, the latter characterized by rapidly progressive crescentic glomerulonephritis combined ...
Nellie Bourse Chalvon +22 more
doaj +3 more sources
Evaluation of the diagnostic performance of an immunoblot for ANCA and anti-GBM antibody detection [PDF]
Autoimmunity, 2021 The use of high-quality antigen-specific immunoassays for detecting anti-neutrophil cytoplasmic antibodies (ANCA) and anti-glomerular basement membrane (GBM) autoantibodies is recommended in patients with suspected ANCA vasculitis and/or anti-GBM disease.
Matthias H. Busch +4 more
doaj +4 more sources
Clinical features and outcome of patients with both ANCA and anti-GBM antibodies [PDF]
Kidney International, 2004 Patients have been described who have both anti-neutrophil cytoplasm antibodies (ANCA) and anti-glomerular basement membrane (GBM) antibodies. We have attempted to define the true prevalence of such "double positive" patients, and describe in detail their clinical features and outcome.We have reviewed all serologic assays performed between 1990 and ...
Charles D Pusey
exaly +3 more sources
Rapid progressive anti-GBM glomerulonephritis with multiple auto-antibodies [PDF]
Journal of Nephropathology, 2020 Rapidly progressive glomerulonephritis (RPGN) is a clinical syndrome manifested by progressive loss of renal function in a short period. At renal biopsy, it is characterized by crescent formation.
David Micarelli +5 more
doaj +4 more sources
Using imlifidase to elucidate the characteristics and importance of anti-GBM antibodies produced after start of treatment [PDF]
Nephrology Dialysis Transplantation, 2023 Fredrik Uhlin +2 more
exaly +2 more sources