Identification of critical residues of linear B cell epitope on Goodpasture autoantigen. [PDF]
PLoS ONE, 2015 BACKGROUND:The autoantigen of anti-glomerular basement membrane (GBM) disease has been identified as the non-collagenous domain 1 of α3 chain of type IV collagen, α3(IV)NC1. Our previous study revealed a peptide on α3(IV)NC1 as a major linear epitope for
Xiao-yu Jia +4 more
doaj +1 more source
IgG anti-apolipoprotein A-1 antibodies in patients with systemic lupus erythematosus are associated with disease activity and corticosteroid therapy: an observational study. [PDF]
, 2015 IgG anti-apolipoprotein A-1 (IgG anti-apoA-1) antibodies are present in patients with systemic lupus erythematosus (SLE) and may link inflammatory disease activity and the increased risk of developing atherosclerosis and cardiovascular disease (CVD) in ...
Davari, M +19 more
core +1 more source
Anti-Saccharomyces cerevisiae antibodies in patients with inflammatory bowel disease and their first-degree relatives: Potential clinical value [PDF]
, 2002 Anti-Saccharomyces cerevisiae antibodies (ASCA) have been described as specific markers in Crohn's disease and their healthy first-degree relatives. 171 patients with Crohn's disease, their 105 first-degree relatives, 145 patients with ulcerative colitis
Török, H.-P. +5 more
core +1 more source
Anti-glomerular Basement Membrane Disease with Atypical Associations
Saudi Journal of Kidney Diseases and Transplantation, 2021 Anti-glomerular basement membrane (anti-GBM) disease is a systemic autoimmune disorder characterized by circulating immunoglobulin (Ig) G antibodies to carboxy-terminal, noncollagenous 1 domain of type IV collagen of GBM.
Prashant Bharat Malviya +3 more
doaj +1 more source
An Unusual Case of Anti-GBM Antibody Elevation in HIV-Associated Nephropathy [PDF]
Case Reports in Nephrology, 2014 Introduction.The most commonly seen glomerular disease in HIV infected patients is HIV-associated nephropathy (HIVAN); however, a multitude of other nephropathies can occur in HIV infection with an almost equal cumulative frequency. We report an unusual case of a patient with clinical and histological evidence of HIVAN in which the diagnosis was ...
Vinay Minocha +2 more
openaire +3 more sources
Granular Immunofluorescence deposition of IgG in anti-GBM antibody disease
Pan African Medical Journal, 2014 Our patient was a 75 year old male, who presented with worsening dysphagia for solids and liquids and increasing malaise. His past medical history was significant for Chronic Obstructive Pulmonary Disease (COPD), Coronary Artery Disease (CAD) and Peripheral Vascular Disease (PVD).
Syed Amer, Mohammed Muqeetadnan
openaire +3 more sources
Stability of important antibodies for kidney disease: pre-analytic methodological considerations [PDF]
PeerJ, 2018 Background The importance of circulating antibodies as biomarkers of kidney disease has recently been recognized. However, no study has systematically described the methodology of sample preparation and storage regarding antibodies as biomarkers of ...
Qiuxia Han +9 more
doaj +2 more sources
Anti-glomerular basement membrane glomerulonephritis in an HIV positive patient: case report
Brazilian Journal of Infectious DiseasesWe report on a case of a patient with HIV infection, diagnosed 18 months prior to the development of an anti-glomerular basement membrane (anti-GBM) rapidly progressive glomerulonephritis; this is probably the first report of such an association.
Eduardo José Bellotto Monteiro +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Plasma from patients with anti-glomerular basement membrane disease could recognize microbial peptides. [PDF]
PLoS ONE, 2017 Infection has long been suspected as a trigger of autoimmune diseases, and molecular mimicry mechanism was hypothesized in this study. Microbe originated peptides were searched from the Uniprot database based on a previous defined critical amino acid ...
Jian-Nan Li +6 more
doaj +1 more source