Results 21 to 30 of about 197,173 (246)

The prevalence and immunological features of anti-glomerular basement membrane antibody in patients with HIV

BMC Nephrology, 2020
Background Anti-glomerular basement membrane disease (GBM) is an autoimmune disease caused by the deposition of circulating anti-GBM antibodies. Non-collagen region of α3 chain of type IV collagen (α3(IV)NC1) is one of the main target antigens, in which ...
Wen-jing Wang, Xiao-yu Jia, Zhao Cui, Yan Chen, Wei Wang, Jin-li Lou, Ming-hui Zhao, Sun Ying   +7 more
doaj   +1 more source

Unleashing the power of complement activation: unraveling renal damage in human anti-glomerular basement membrane disease

Frontiers in Immunology, 2023
Anti-glomerular basement membrane (GBM) disease is a rare but life-threatening autoimmune disorder characterized by rapidly progressive glomerulonephritis with or without pulmonary hemorrhage. Renal biopsies of anti-GBM patients predominantly show linear
Anqi Tang, Xin Zhao, Tian Tao, Dengpiao Xie, Bojun Xu, Youqun Huang, Mingquan Li   +6 more
doaj   +1 more source

Detection of injected anti-HS antibodies, rabbit IgG and complement C3c in mouse glomeruli after anti-GBM-induced glomerulonephritis.

, 2021
Representative immunofluorescence stainings for (A) anti-HS antibodies with anti-VSV in glomeruli of mice co-injected with anti-GBM IgG serum and anti-HS antibodies, 2 hours after injection (40x magnification), (B) Staining for rabbit IgG in glomeruli of
Toin H. van Kuppevelt (10013111), Nathalie J. H. G. Passmann (11873757), Markus A. Loeven (3368984), Jasper J. van Gemst (3368987), Bart Smeets (170582), Johan van der Vlag (45996), Jo H. Berden (11873763), Ton J. Rabelink (8695392), Angelique L. W. M. M. Rops (11873760)   +8 more
core   +1 more source

IgA nephropathy and atypical anti GBM disease: A rare dual pathology in a pediatric RPGN

Glomerular Diseases, 2021
Introduction: Anti-GBM nephritis in the pediatric age group is exceedingly rare with concurrent additional pathologies being even rarer. Tissue diagnosis requires a combination of crescentic histomorphology, immunofluorescence showing “Paint brush stroke”
Varun Bajaj, Shilpi Thakur, Adarsh Barwad, Aditi Sinha, Arvind Bagga, Geetika Singh   +5 more
doaj   +1 more source

Long-term outcome of anti-glomerular basement membrane antibody disease treated with immunoadsorption. [PDF]

PLoS ONE, 2014
Anti-glomerular basement membrane (GBM) antibody disease may lead to acute crescentic glomerulonephritis with poor renal prognosis. Current therapy favours plasma exchange (PE) for removal of pathogenic antibodies.
Peter Biesenbach, Renate Kain, Kurt Derfler, Thomas Perkmann, Afschin Soleiman, Alexandra Benharkou, Wilfred Druml, Andrew Rees, Marcus D Säemann   +8 more
doaj   +1 more source

Pulmonary-Renal Syndrome with Negative ANCAs and Anti-GBM Antibody [PDF]

Case Reports in Nephrology, 2013
We report the case of a 76-year-old woman who was referred to our hospital for a gradually worsening cough and renal dysfunction. Although pneumonia was initially suspected, imaging findings of the lungs revealed diffuse alveolar hemorrhage at a later date. Renal failure developed and hemodiafiltration was performed on the 9th day.
Hiroshi Yamaguchi, Atsuhisa Shirakami, Takashi Haku, Takashige Taoka, Yoshikazu Nakanishi, Toru Inai, Takanori Hirose   +6 more
openaire   +4 more sources

The development of rapidly progressive glomerulonephritis associated with both antineutrophil cytoplasmic antibody-associated vasculitis and anti-glomerular basement membrane nephritis in the course of nontuberculous mycobacterium infection: a case report

BMC Rheumatology, 2020
Background Antineutrophil cytoplasmic antibodies (ANCA) and Anti-glomerular basement membrane (GBM) antibodies often induce rapidly progressive glomerulonephritis (RPGN).
Mikiya Kato, Risa Wakiya, Tomohiro Kameda, Kousuke Inoue, Tadashi Sofue, Yusuke Ushio, Koichi Sugihara, Shusaku Nakashima, Hiromi Shimada, Mai Mahmoud Fahmy Mansour, Norimitsu Kadowaki, Hiroaki Dobashi   +11 more
doaj   +1 more source

A case report of atypical anti-glomerular basement membrane disease

BMC Nephrology, 2022
Background Anti-glomerular basement membrane (anti-GBM) disease is characterized by crescentic necrotizing glomerulonephritis, with linear deposits of immunoglobulin G (IgG) in the GBM.
Ryo Tamura, Toshiki Doi, Shuma Hirashio, Kensuke Sasaki, Yukinari Masuda, Akira Shimizu, Takao Masaki   +6 more
doaj   +1 more source

Splenic Infarcts and Pulmonary Renal Syndrome in a Young Patient with Double-Positive Anti-GBM and ANCA-Associated Vasculitis

Saudi Journal of Kidney Diseases and Transplantation, 2021
Double-positive disease, defined by double-seropositivity for serum anti-glomerular basement membrane (GBM) antibodies and anti-neutrophil cytoplasmic antibodies (ANCA) is a rare cause of pulmonary-renal syndrome.
Fares T Rajah, Ali A Alhabobi, Noura M Aloudah, Ayumun I Osman, Elwaleed A Elhassan   +4 more
doaj   +1 more source

Co-injection of anti-HS antibodies during anti-GBM-induced glomerulonephritis induces a transient increase in albuminuria and decline in renal function.

, 2021
Blood urea nitrogen (BUN) levels after (A) 2 hours, (B) 1 day and (C) 4 days. Urinary albumin concentration after 2 hours (D) and urinary albumin:creatinine ratios after (E) 1 day and (F) 4 days anti-GBM-induced glomerulonephritis.
Toin H. van Kuppevelt (10013111), Nathalie J. H. G. Passmann (11873757), Markus A. Loeven (3368984), Jasper J. van Gemst (3368987), Bart Smeets (170582), Johan van der Vlag (45996), Jo H. Berden (11873763), Ton J. Rabelink (8695392), Angelique L. W. M. M. Rops (11873760)   +8 more
core   +1 more source