Results 131 to 140 of about 197,173 (246)

Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 7, July 2026.
Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen, Yupan Bai, Lu Shen, Jiacheng Ying, Jie Xu, Jiayin Tang, Yujie Bao   +6 more
wiley   +1 more source

Mitigated Clinical Course of Crescentic Glomerulonephritis with Positive Anti-Glomerular Basement Membrane Antibodies in a 14-Year-Old Girl

Glomerular Diseases
Introduction: Anti-glomerular basement membrane (anti-GBM) glomerulonephritis is associated with severe kidney failure and high morbidity and is exceedingly rare in children.
Noortje M. Van Der Meulen, Michiel J.S. Oosterveld, Marjolijn S.W. Quaak, Ester M.M. van Leeuwen, Joris J.T.H. Roelofs, Rik Westland   +5 more
doaj   +1 more source

Efficacy and immunogenic effects of Tumor Treating Fields (TTFields) in preclinical models of pancreatic ductal adenocarcinoma, with and without gemcitabine/nab‐paclitaxel

International Journal of Cancer, Volume 158, Issue 12, Page 3091-3100, 15 June 2026.
What's new? Adaptive immune responses are typically limited in pancreatic ductal adenocarcinoma, resulting in minimal efficacy of immune checkpoint inhibitors. Tumor Treating Fields (TTFields) therapy, which uses low‐intensity intermediate‐frequency electric fields to disrupt cancer cell processes, has been approved for certain cancers.
Tal Kan, Tharwat Haj Khalil, Yiftah Barsheshet, Tali Voloshin, Lilach Koren, Bella Koltun, Cfir David, Kerem Wainer‐Katsir, Avital Vorontsova, Boris Brant, Simona Zisman‐Rozen, Hila M. Ene, Roni Frechtel‐Gerzi, Shay Cahal, Anat Klein‐Goldberg, Lena Lifshitz, Efrat Zemer Tov, Mai Shai, Adi Haber, Moshe Giladi, Uri Weinberg, Yoram Palti   +21 more
wiley   +1 more source

Antigen and epitope specificity of anti-glomerular basement membrane antibodies in patients with Goodpasture disease with or without anti-neutrophil cytoplasmic antibodies

, 2007
Goodpasture disease (GP) is defined by the presence of anti-glomerular basement membrane (anti-GBM) antibodies and rapidly progressive glomerulonephritis. Besides anti-GBM, many patients with GP produce anti-neutrophil cytoplasmic antibodies (ANCA).
Cui, Zhao, Wang, Hai-yan, Zhao, Juan, Rui Yang, Hellmark, Thomas, Hai-yan Wang, Zhao, Ming-hui, Zhao Cui, Juan Zhao, Ming-hui Zhao, Yang, Rui, Segelmark, Mårten, Marten Segelmark, Thomas Hellmark   +13 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, Volume 20, Issue 6, Page 1420-1428, June 2026.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

A rare case of sero-negative anti-glomerular basement membrane disease combined with diabetic nephropathy and literature review

Renal Failure
We report a case of a 59-year-old male who exhibited an insidious onset of hematuria, nephrotic syndrome, and mild renal dysfunction, with negative serum anti-glomerular basement membrane antibodies.
Wenbo Wang, Weiyi Guo, Xiaoyi Xu, Nan Ye, Lingqiang Kong, Guoqin Wang, Hong Cheng   +6 more
doaj   +1 more source

Membranous Nephropathy Due to Anti-GBM Antibodies of Mice and Men [PDF]

American Journal of Nephrology, 2020
openaire   +2 more sources

Biomimetic Nanovaccine Integrating Dendritic Cell Exosomes with Tumor Cell Membranes for Sustained Prophylaxis Against Glioblastoma

Advanced Functional Materials, Volume 36, Issue 48, 15 June 2026.
We have developed DEX/GM, an all‐natural, personalizable hybrid vaccine designed by coating dendritic cell‐derived exosomes (DEX) onto tumor cell membranes (GM) for sustained prophylaxis against glioblastoma (GBM). ABSTRACT Glioblastoma (GBM), one of the most aggressive and lethal brain tumors, remains incurable with a poor clinical prognosis.
Shanshan Li, Dongya Zhang, Shiyu Wang, Changhe Pang, Meng Zheng, Bingyang Shi, Yan Zou   +6 more
wiley   +1 more source

Analytical Performance of a Novel, Fully Automated Multiplexed Microarray Immunoassay for the Simultaneous Detection of Anti-PR3, Anti-MPO, and Anti-GBM Autoantibodies

Journal of Clinical Rheumatology and Immunology
Background: Autoantibodies against myeloperoxidase (MPO), proteinase 3 (PR3), and glomerular basement membrane (GBM) are critical diagnostic markers for ANCA-associated vasculitides—microscopic polyangiitis (MPA), granulomatosis with polyangiitis (GPA ...
Jason Sillitoe, Caroline Wilson, Ewa Garyga, Pedro Silva, Kristiana Nita, Ewa Fiorentino-Rozek, Jose Santiago, Gerber Gomez, Christian Fischer, John Tyson, Makoto Miyara   +10 more
doaj   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source