Results 141 to 150 of about 197,173 (246)
A relapsing case of pulmonary-renal syndrome after a sequential rise in MPO-ANCA and anti-GBM antibodies. [PDF]
CEN Case Rep, 2019 Hoshino A +8 more
europepmc +1 more source
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Advanced Healthcare Materials, Volume 15, Issue 22, 12 June 2026.Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source
Characterisation of HLA-specific antibodies [PDF]
A successful kidney transplant is the best treatment for established renal failure, yet around 300 patients per annum are denied transplants because they have antibodies, most notably directed against donor HLA or ABO in their blood, which have the ...
Lowe, David Philip
core
Advanced Science, Volume 13, Issue 34, 19 June 2026.ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang +9 more
wiley +1 more source
ECMO-dependent respiratory failure after snorting speed associated with anti-GBM antibodies. [PDF]
Respirol Case Rep, 2015 De Rosa N, Glanville A.
europepmc +1 more source
Advanced Science, Volume 13, Issue 31, 4 June 2026.Although the tumor microenvironment is known to shape immunotherapy response, its key determinants remain elusive, underscoring the critical need for single‐cell resolution analytical frameworks. We present scResponse, an efficient algorithm to quantify single‐cell responses to immunotherapy. By capturing diverse cellular subtypes and states associated
Qi Dong +21 more
wiley +1 more source
Integrating Oncolytic Virus Engineering and Delivery Strategies for Enhanced Cancer Virotherapy
Aggregate, Volume 7, Issue 6, June 2026.Integrated engineering strategies combining oncolytic virus (OV) design with advanced delivery platforms overcome biological barriers and enhance cancer virotherapy. Genetic engineering improves viral potency and selectivity, while local and systemic delivery systems promote viral protection, tumor targeting, penetration, and tumor microenvironment ...
Jiliang Zhao +5 more
wiley +1 more source
Cancer Medicine, Volume 15, Issue 6, June 2026.ABSTRACT Background Shugoshin proteins SGO1 and SGO2 regulate chromosome cohesion and segregation during mitosis and meiosis, and their aberrant expression is implicated in several cancers. However, the mechanistic involvement of these two proteins in papillary renal cell carcinoma (KIRP) and their contribution to immune evasion remains unclear ...
Han Fu +7 more
wiley +1 more source
Metastatic cancer and anti-GBM disease, a rare but possible entity : A case report
Academic Medicine & Surgery# Background Anti-GBM (anti–glomerular basement membrane antibodies) glomerulonephritis, also known as Goodpasture’s syndrome, is a rare autoimmune condition that has been rarely reported in association with malignancies or immune checkpoint inhibitor ...
Salima Serroukh +5 more
doaj +1 more source
Cancer Medicine, Volume 15, Issue 6, June 2026.High C1orf226 expression correlates with glioma aggressiveness and worse prognosis. C1orf226 promotes malignant phenotypes and stemness in glioma cells. C1orf226 interacts with PLK1 to stabilize β‐catenin and activate the Wnt/β‐catenin pathway. ABSTRACT Introduction Glioma stem cells (GSCs) are pivotal drivers of tumor progression and therapeutic ...
Yanbing Lu +6 more
wiley +1 more source