Results 91 to 100 of about 24,523 (202)
Role of RIPK1/RIPK3/MLKL signalling pathway in sepsis‐associated acute kidney injury
Experimental Physiology, EarlyView.Abstract Sepsis‐associated acute kidney injury (SA‐AKI) is a common clinical syndrome in critically ill patients, and its high mortality rate is closely related to complex pathological mechanisms. Existing studies have shown that the pathophysiological process of SA‐AKI involves complex multi‐mechanism interactions, including an uncontrolled systemic ...
Huijun Yin, Jingyi Wang, Huirong Han
wiley +1 more source
Epidemiology, Impact, and Management Strategies of Anti-Glomerular Basement Membrane Disease
International Journal of Nephrology and Renovascular Disease, 2022 Muhammad Asim,1 Mohammed Akhtar2 1Division of Nephrology, Department of Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar; 2Department of Laboratory Medicine and Pathology, Hamad General Hospital, Hamad Medical Corporation, Doha ...
Asim M, Akhtar M
doaj
Experimental Physiology, EarlyView.ABSTRACT Acute kidney injury (AKI) is a global health problem with significant long‐term harm if the prognosis is poor. Dual‐specificity phosphatase 2 (DUSP2) is involved in key regulatory pathways in several disease processes, but its function in renal pathophysiology is unclear.
Xueqian Chu +8 more
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Advanced Science, Volume 13, Issue 31, 4 June 2026.RENAL‐CHIP converts 1 mL of peripheral blood into a biopsy‐equivalent readout of renal‐allograft fate. By magnetic capture and release of donor‐derived circulating podocytes through a herringbone microfluidic chip, 84% capture, 96% release and single‐cell RNA evidence of rejection‐specific immunity are achieved.
Juan Song +11 more
wiley +1 more source
, 2012 Anti-glomerular basement membrane antibody disease is a rare, but well characterized cause of glomerulonephritis. By definition serum anti-GBM antibody and/or a linear binding of IgG detected by direct immunofluorescence (IF) in a histological specimen ...
Lahmer, T;Heemann, U
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Journal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.These findings indicate that urinary exosomal miR‐217 promotes podocyte ferroptosis and DKD progression via suppression of the SIRT1/Nrf2 pathway, suggesting a potential therapeutic target for DKD. Abstract Urinary exosomal microRNAs (miRNAs) mediate intercellular communication in diabetic kidney disease (DKD), a leading contributor to end‐stage renal ...
Xin Du +7 more
wiley +1 more source
Complement in anti-glomerular basement membrane glomerulonephritis [PDF]
Anti-glomerular basement membrane glomerulonephritis (anti-GBM GN) is a rare autoimmune disease that often progresses to end-stage renal disease (ESRD).
Kai-li Shi +5 more
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, 2020 Anti–glomerular basement membrane disease can rapidly lead to renal failure and blood pressure dysregulation. A rare complication is hypertensive encephalopathy in the form of seizures.
Joshua Mathews +3 more
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, 2009 Anti-glomerular basement membrane disease is a rare autoimmune disease characterized by rapidly progressive renal failure and/or pulmonary hemorrhage. The presence of severe crescentic glomerular inflammation with linear deposition of immunoglobulin G ...
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The role of cytosolic RNA and DNA recognition in systemic autoimmunity and immune complex glomerulonephritis [PDF]
, 2010 Non-CpG-DNA and 3P-RNA activated mesangial cells to produce inflammatory cytokines and type 1 interferons in TLR-independent manner. Both ligands induced similar gene expression patterns in mesangial cells.
Ramanjaneyulu, Allam
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