Results 111 to 120 of about 338,197 (344)
Engineering CAR T Cells to Target the HIV Reservoir
Frontiers in Cellular and Infection Microbiology, 2020 The HIV reservoir remains to be a difficult barrier to overcome in order to achieve a therapeutic cure for HIV. Several strategies have been developed to purge the reservoir, including the “kick and kill” approach, which is based on the notion that ...
Wenli Mu +2 more
doaj +1 more source
Study of Some Analogue of Currently Cilinically used Pyrazinamide Compounds [PDF]
, 2015 There has been considerable interest in the development of new compounds with anti mycobacterial activity particularly against multidrug resistance (MDR) and extensively drug resistant (XDR) tuberculosis (TB) because mycobacterium species have developed ...
Asif, Mohammad
core +1 more source
Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies
Chemistry &Biodiversity, EarlyView.Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang +8 more
wiley +1 more source
A dynamic theory of fidelity networks with an application to the spread of HIV/AIDS [PDF]
We study the dynamic stability of fidelity networks, which are networks that form in a mating economy of agents of two types (say men and women), where each agent desires direct links with opposite type agents, while engaging in multiple partnerships is ...
Roberto Serrano, Roland Pongou
core
Focus on chirality of HIV-1 non-nucleoside reverse transcriptase inhibitors [PDF]
, 2016 Chiral HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are of great interest since one enantiomer is often more potent than the corresponding counterpart against the HIV-1 wild type (WT) and the HIV-1 drug resistant mutant strains.
Famiglini, Valeria, Silvestri, Romano
core +2 more sources
Staphylococcus Aureus AgrA Modulators from South African Antimicrobial Plants.
Chemistry &Biodiversity, Accepted Article.South African plants are an underutilized metabolites source for novel antimicrobials targeting key quorum sensing (QS) systems like the Staphylococcus aureus AgrA. AgrA modulating metabolites constitute a new approach to reducing resistance development.
Christiana Eleojo Aruwa, Saheed Sabiu
wiley +1 more source
LMP-420, a small-molecule inhibitor of TNF-alpha, reduces replication of HIV-1 and Mycobacterium tuberculosis in human cells [PDF]
, 2006 BACKGROUND: Co-infections of human immunodeficiency virus (HIV) and Mycobacterium tuberculosis (M. Tb) are steadily increasing and represent a major health crisis in many developing countries.
Beigier-Pompadre, Macarena +8 more
core +3 more sources
VAIN: Attentional Multi-agent Predictive Modeling [PDF]
arXiv, 2017 Multi-agent predictive modeling is an essential step for understanding physical, social and team-play systems. Recently, Interaction Networks (INs) were proposed for the task of modeling multi-agent physical systems, INs scale with the number of interactions in the system (typically quadratic or higher order in the number of agents).
arxiv
Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential
ChemBioEng Reviews, EarlyView.This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona +2 more
wiley +1 more source
Languages for Mobile Agents [PDF]
arXiv, 2015 Mobile agents represent a new model for network computing. Many different languages have been used to implement mobile agents. The characteristics that make a language useful for writing mobile agents are: (1) their support of agent migration, (2) their support for agent-to-agent communication, (3) how they allow agents to interact with local resources,
arxiv