Results 211 to 220 of about 686,239 (385)

Advancements in development of novel class of HIV protease inhibitors. [PDF]

Ann Med
Gu WG, Yin GZ, Zhang YP.
europepmc   +1 more source

Lung organoids as a human system for Mycobacteria infection modeling and drug testing

The FEBS Journal, EarlyView.
Mycobacterial infections, including tuberculosis (TB) and infections by nontuberculous mycobacteria (NTM), are still public health issues. In 2023, TB caused 1.25 million deaths, while NTM remain a clinical challenge for patients with cystic fibrosis (CF).
Stephen Adonai Leon‐Icaza, Romain Vergé, Raoul Mazars, Laurence Berry, Céline Cougoule   +4 more
wiley   +1 more source

Serology change-based clinical interpretation of indeterminate serostatus post-hepatitis B virus infection in people living with HIV. [PDF]

PLoS One
Kinai E, Ishikura M, Miyashita R, Yamaguchi T, Chikasawa Y, Ichiki A, Sekiya R, Bingo M, Muramatsu T, Yotsumoto M, Hagiwara T, Amano K.   +11 more
europepmc   +1 more source

Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription

, 2017
Tsuyoshi Hayashi, Maxime Jean, Huachao Huang, Sydney Simpson, Netty Santoso, Jian Zhu   +5 more
openalex   +2 more sources

Leishmania donovani's protein tyrosine phosphatases interact with DUF21 and respond to environmental magnesium

The FEBS Journal, EarlyView.
The Leishmania phosphatase PTP1, and possibly the genetically similar PTP2, interacts with the Leishmania transmembrane protein DUF21. When both ptp1 and ptp2 are knocked out of Leishmania (LdΔPTP1/2), the parasite can no longer survive without magnesium in vitro and has reduced viability in the host macrophage. Conversely, in duf21 knockout (LdΔDUF21),
Kayla Paulini, Hira Khursheed, Wen Wei Zhang, Isabelle Aubry, Greg Matlashewski, Michel L. Tremblay, Patrick Lypaczewski   +6 more
wiley   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Background HIV Incidence in PURPOSE 1 and 2 PrEP Trials. [PDF]

Clin Infect Dis
Parienti JJ.
europepmc   +1 more source

Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity [PDF]

, 2015
Chunte Sam Peng, Bogdan I. Fedeles, Vipender Singh, Deyu Li, Tiffany Amariuta, John M. Essigmann, Andrei Tokmakoff   +6 more
openalex   +1 more source

Polypharmacy in HIV: Rethinking what counts and why it matters

HIV Medicine, EarlyView.
Abstract Polypharmacy, the concurrent use of multiple medications, presents a growing challenge in HIV care as people living with HIV age and experience earlier onset of age‐related co‐morbidities. However, how polypharmacy is defined and assessed in HIV research remains inconsistent.
Luxsena Sukumaran, Alan Winston, Catia Marzolini, Saye Khoo, Marta Boffito, Nadia Naous, Caroline A. Sabin   +6 more
wiley   +1 more source

A Case of Fulminant Amebiasis in a Female Commercial Sex Worker in Japan Requiring Subtotal Colectomy: A Literature Review and Case Report. [PDF]

Surg Case Rep
Kubota S, Mihara F, Nakamura M, Kokudo T, Mihara Y, Inagaki F, Kokudo N.   +6 more
europepmc   +1 more source