Results 31 to 40 of about 338,197 (344)

Physical, motor and biochemistry assessments of children exposed to HIV

Scientific Electronic Archives, 2019
According to data from the Ministry of Health, the number of HIV positive pregnant women is still worrying, so it is necessary to carry out targeted care for these children exposed to HIV, assessing their development and growth thus promoting a normal ...
A. P. P. Cardoso, T. R. Pegorete, P. O. Silva, P. P. Cavalcanti   +3 more
doaj   +1 more source

Electrochemistry of anti-HIV agents

Electrochemistry Communications, 2000
Square wave voltammetry has been used to study the electrochemical behaviour of anti-HIV drugs in aqueous solutions. The oxidation reaction of Carbovir (1) at a Pt microelectrode occurs at 1.12 V versus SCE and the peak current is proportional to the concentration. An electroanalytical technique for the determination of trace concentrations of Carbovir
Yufei Cheng, S.C. Lemoult, David J. Schiffrin, Kyösti Kontturi   +3 more
openaire   +2 more sources

Oropharyngeal Candidosis in HIV-Infected Patients—An Update

Frontiers in Microbiology, 2018
Oropharyngeal candidosis (OPC) is an opportunistic fungal infection that is commonly found in HIV-infected patients, even in the twenty-first century. Candida albicans is the main pathogen, but other Candida species have been isolated.
Shankargouda Patil, Barnali Majumdar, Sachin C. Sarode, Gargi S. Sarode, Kamran H. Awan   +4 more
doaj   +1 more source

The inhibitor of apoptosis proteins antagonist Debio 1143 promotes the PD-1 blockade-mediated HIV load reduction in blood and tissues of humanized mice.

PLoS ONE, 2020
The immune checkpoint programmed cell death protein 1 (PD-1) plays a major role in T cell exhaustion in cancer and chronic HIV infection. The inhibitor of apoptosis protein antagonist Debio 1143 (D1143) enhances tumor cell death and synergizes with anti ...
Michael Bobardt, Joseph Kuo, Udayan Chatterji, Norbert Wiedemann, Gregoire Vuagniaux, Philippe Gallay   +5 more
doaj   +1 more source

Design, Synthesis, and Mechanistic Study of 2-Pyridone-Bearing Phenylalanine Derivatives as Novel HIV Capsid Modulators

Molecules, 2022
The AIDS pandemic is still of importance. HIV-1 and HIV-2 are the causative agents of this pandemic, and in the absence of a viable vaccine, drugs are continually required to provide quality of life for infected patients.
Xujie Zhang, Lin Sun, Shujing Xu, Xiaoyu Shao, Ziyi Li, Dang Ding, Xiangyi Jiang, Shujie Zhao, Simon Cocklin, Erik De Clercq, Christophe Pannecouque, Alexej Dick, Xinyong Liu, Peng Zhan   +13 more
doaj   +1 more source

Antiviral and ROS scavenging potential of Carica papaya Linn and Psidium guajava leaves extract against HIV-1 infection

BMC Complementary Medicine and Therapies, 2023
Antiretroviral therapy is the only treatment option for HIV-infected patients; however, it has certain drawbacks in terms of developing multiple toxic side effects.
Pratiksha Jadaun, Prachibahen Shah, R. Harshithkumar, Madhukar S. Said, Shubhangi P. Bhoite, Sowmya Bokuri, Selvan Ravindran, Neetu Mishra, Anupam Mukherjee   +8 more
doaj   +1 more source

Small-Molecule Anti-HIV-1 Agents Based on HIV-1 Capsid Proteins

Biomolecules, 2021
The capsid of human immunodeficiency virus type 1 (HIV-1) is a shell that encloses viral RNA and is highly conserved among many strains of the virus. It forms a conical structure by assembling oligomers of capsid (CA) proteins. CA dysfunction is expected
Takuya Kobayakawa, Masaru Yokoyama, Kohei Tsuji, Masayuki Fujino, Masaki Kurakami, Sayaka Boku, Miyuki Nakayama, Moemi Kaneko, Nami Ohashi, Osamu Kotani, Tsutomu Murakami, Hironori Sato, Hirokazu Tamamura   +12 more
doaj   +1 more source

Seroprevalence pattern among blood donors in a tertiary health care center [PDF]

, 2014
Although blood transfusion is a life-saving maneuver, it is associated with certain risks. In general, transfusion-related adverse events are categorized as infectious and noninfectious.
Butola, KS, Kumar, S, Kumar, Y, Mishra, JP, Sethi, B   +4 more
core   +2 more sources

Strategies in the Design of Prodrugs of Anti-HIV Agents

Current Topics in Medicinal Chemistry, 2003
Control of AIDS requires development of special therapeutic strategies in order to reduce the level of monocyte/macrophage HIV infection, to prevent spread of HIV within the monocyte/macrophage reservoir, to maintain a therapeutically effective drug concentration in sanctuaries such as the brain and to overcome the problem of cellular resistance ...
Calogeropoulou, Theodora, Detsi, A., Lekkas, E., Koufaki, Maria   +3 more
openaire   +3 more sources

MORONIC ACID: A REVIEW [PDF]

, 2021
Moronic acid is a pentacyclic triterpenoid made up of olean-18-ene with an oxo group at position 3 and a carboxy group at position 28. It's made from an oleanane hydride.
RANI, RITU, SINGH, AJEET PAL, SINGH, AMAR PAL   +2 more
core   +1 more source