Results 31 to 40 of about 492,595 (235)

Waking Up the Sleepers: HIV Latency and Reactivation

Journal of the Formosan Medical Association, 2008
In a patient infected with HIV-1, the presence of latently infected cells from which the virus can be reactivated and rekindle HIV infection in the patient necessitates lifelong administration of antiretroviral treatment.
Hoi Ping Mok, Andrew Lever
doaj   +1 more source

Computationally-Guided Optimization of a Docking Hit to Yield Catechol Diethers as Potent Anti-HIV Agents [PDF]

Journal of Medicinal Chemistry, 2011
Mariela Bollini, Robert A. Domaoal, Vinay V. Thakur, Ricardo Gallardo‐Macias, Krasimir A. Spasov, Karen S. Anderson, William L. Jorgensen   +6 more
openalex   +2 more sources

Otolaryngologic manifestations in HIV disease: clinical aspects and treatment Manifestações otorrinolaringológicas na infecção pelo HIV: aspectos clínicos e terapêuticos

Brazilian Journal of Otorhinolaryngology, 2011
HIV is a pandemic infection with cases notified in almost all countries. The reported prevalence of symptoms in the head and neck is about 80%; otolaryngologists may be the first physician to see such patients.
Fernanda Alves Sanjar, Barbara Elvina Ulisses Parente Queiroz, Ivan Dieb Miziara   +2 more
doaj   +1 more source

Design, synthesis, molecular dynamics studies and biological evaluations of 4-hydroxy-5-pyrrolinone-3-carbohydrazides as HIV-1 integrase inhibitors

European Journal of Medicinal Chemistry Reports
Acquired immune deficiency syndrome (AIDS) diseases despite the efficacy of anti-HIV therapy, remain one of the human's most serious problems. Hence, the introduction of novel anti-HIV agents as first-line therapy is still required. HIV integrase lacking
Nafiseh Karimi, Amirreza Dowlati Beirami, Rouhollah Vahabpour Roudsari, Zahra Hajimahdi, Afshin Zarghi   +4 more
doaj   +1 more source

Dendrimers as Potential Therapeutic Tools in HIV Inhibition

Molecules, 2013
The present treatments for HIV transfection include chemical agents and gene therapies. Although many chemical drugs, peptides and genes have been developed for HIV inhibition, a variety of non-ignorable drawbacks limited the efficiency of these ...
Xiangbo Li, Yi Chen, Xiaole Qi, Zhenghong Wu, Jianqing Peng   +4 more
doaj   +1 more source

Induction maintenance concept for HAART as initial treatment in HIV infected infants

European Journal of Medical Research, 2011
Background Early initiated antiretroviral therapy (ART) in HIV infected infants leads to improved long-term viral suppression and survival. Guidelines recommend initiating therapy with a triple ART consisting of two nucleoside reverse transcriptase ...
Ghosh S, Neubert J, Niehues T, Adams O, Morali-Karzei N, Borkhardt A, Laws HJ   +6 more
doaj   +1 more source

Targeting the PI3K/Akt cell survival pathway to induce cell death of HIV-1 infected macrophages with alkylphospholipid compounds. [PDF]

PLoS ONE, 2010
HIV-1 infected macrophages and microglia are long-lived viral reservoirs persistently producing viral progenies. HIV-1 infection extends the life span of macrophages by promoting the stress-induced activation of the PI3K/Akt cell survival pathway ...
Amanda Lucas, Yuri Kim, Omayra Rivera-Pabon, Sunju Chae, Dong-Hyun Kim, Baek Kim   +5 more
doaj   +1 more source

Highly Efficient Chemoprophylaxis of Perinatal Transmission of HIV 1 Infection in HIV-Infected Pregnant Women

Антибиотики и Химиотерапия, 2020
Prevention of HIV infection perinatal transmission with specific anti-HIV agents is at present effective and resultant. The use of retrovir and nevirapin in such cases is well known and approved.
G. A. Galegov
doaj  

Anti-HIV-1 activity of a new scorpion venom peptide derivative Kn2-7. [PDF]

PLoS ONE, 2012
For over 30 years, HIV/AIDS has wreaked havoc in the world. In the absence of an effective vaccine for HIV, development of new anti-HIV agents is urgently needed.
Yaoqing Chen, Luyang Cao, Maohua Zhong, Yan Zhang, Chen Han, Qiaoli Li, Jingyi Yang, Dihan Zhou, Wei Shi, Benxia He, Fang Liu, Jie Yu, Ying Sun, Yuan Cao, Yaoming Li, Wenxin Li, Deying Guo, Zhijian Cao, Huimin Yan   +18 more
doaj   +1 more source

An Artificial Peptide-Based Bifunctional HIV-1 Entry Inhibitor That Interferes with Viral Glycoprotein-41 Six-Helix Bundle Formation and Antagonizes CCR5 on the Host Cell Membrane

Viruses, 2023
Human immunodeficiency virus type 1 (HIV-1) is characterized by high variability and drug resistance. This has necessitated the development of antivirals with a new chemotype and therapy.
Chao Wang, Qing Li, Lujia Sun, Xinling Wang, Huan Wang, Wenpeng Zhang, Jiahui Li, Yang Liu, Lu Lu, Shibo Jiang   +9 more
doaj   +1 more source