Results 71 to 80 of about 338,197 (344)

Retinoids: novel potential therapeutics in the pursuit of HIV-1 cure

Frontiers in Virology, 2022
Human immunodeficiency virus (HIV) infection remains a global epidemic. While antiretroviral therapy (ART) suppresses viral replication, cessation of ART results in viral rebound necessitating lifelong treatment.
Andrew Purssell, Michaeline McGuinty, Michaeline McGuinty, Branka Vulesevic, Jonathan B. Angel, Jonathan B. Angel   +5 more
doaj   +1 more source

A PERSPECTIVE ON ANTIINFECTIVE AGENTS INTERACTION IN HUMAN IMMUNODEFICIENCY VIRUS PATIENTS WITH MALARIAL INFECTION [PDF]

, 2016
Despite recent research advances in anti-infective agents (achievements), Human immunodeficiency virus (HIV), and malaria infection are currentlyconsidered two main global human health problems. Given the considerable geographical overlap between malaria
Bhopale, Girish M
core   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source

Coumarins as anti-HIV agent and correlation with COVID-19: an overview

HIV & AIDS Review. International Journal of HIV-Related Problems, 2023
Acquired immunodeficiency syndrome (AIDS) is an immunosuppressive disease caused by human immunodeficiency virus (HIV), and leads to infection and malignance, which are life threatening.
Vikas Kumar, Harish Joshi, Inder Prasad Pandey, Sanjay Kumar   +3 more
doaj   +1 more source

Rheumatic conditions in human immunodeficiency virus infection [PDF]

, 2017
Many rheumatic diseases have been observed in HIV-infected persons. We, therefore, conducted a comprehensive literature search in order to review the prevalence, presentation and pathogenesis of rheumatic manifestations in HIV-infected subjects ...
Daikeler, T., Tyndall, A., Walker, U. A.
core  

Virtual Screening of acyclovir derivatives as potential antiviral agents: design, synthesis, and biological evaluation of new acyclic nucleoside ProTides [PDF]

, 2017
Following our findings on the anti-human immunodeficiency virus (HIV) activity of acyclovir (ACV) phosphate prodrugs, we herein report the ProTide approach applied to a series of acyclic nucleosides aimed at the identification of novel and selective ...
Andrea Brancale, Christophe Vanpouille, Christopher McGuigan, Copeland W. C., Davide Carta, Graciela Andrei, Jan Balzarini, Leonid Margolis, Marco Derudas, Parker W. B., Robert Snoeck, Sonia Zicari   +11 more
core   +5 more sources

"I Don't Think So": Summarizing Policy Disagreements for Agent Comparison [PDF]

arXiv, 2021
With Artificial Intelligence on the rise, human interaction with autonomous agents becomes more frequent. Effective human-agent collaboration requires users to understand the agent's behavior, as failing to do so may cause reduced productivity, misuse or frustration.
arxiv  

When Do Introspection Axioms Matter for Multi-Agent Epistemic Reasoning? [PDF]

EPTCS 297, 2019, pp. 121-139, 2019
The early literature on epistemic logic in philosophy focused on reasoning about the knowledge or belief of a single agent, especially on controversies about "introspection axioms" such as the 4 and 5 axioms. By contrast, the later literature on epistemic logic in computer science and game theory has focused on multi-agent epistemic reasoning, with the
arxiv   +1 more source

The Effect of Zoledronic Acid on Bone Microarchitecture and Strength after Denosumab and Teriparatide Administration: DATA‐HD Study Extension

Journal of Bone and Mineral Research, Volume 38, Issue 1, Page 26-34, January 2023., 2023
ABSTRACT The combination of denosumab and teriparatide is an effective treatment strategy in postmenopausal osteoporosis, though skeletal gains are promptly lost when these agents are discontinued. In the DATA‐HD study, we reported that a single dose of zoledronic acid (ZOL) maintains the increases in areal spine and hip bone mineral density (BMD ...
Sabashini K. Ramchand, Natalie L. David, Hang Lee, Michael Bruce, Mary L. Bouxsein, Joy N. Tsai, Benjamin Z. Leder   +6 more
wiley   +1 more source

Dual-acting stapled peptides target both HIV-1 entry and assembly [PDF]

, 2013
Background: Previously, we reported the conversion of the 12-mer linear and cell-impermeable peptide CAI to a cell-penetrating peptide NYAD-1 by using an i,i + 4 hydrocarbon stapling technique and confirmed its binding to the C-terminal domain (CTD ...
Bhargava, P., Cooper, A., Curreli, F., Debnath, A.K., Freed, E.O., Lee, S., Mehta, M., Mercredi, P.Y., Scacalossi, D., Summers, M.F., Tong, X., Waheed, A.A., Zhang, H.   +12 more
core   +2 more sources