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Idiopathic Inflammatory Myopathies-Treatment Perspective of Highly Specialised Rheumatology Centre. [PDF]
J Clin MedDutsch-Wicherek M +2 more
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High-plex spatial protein profiling of skeletal muscle biopsies in inflammatory myopathies using the MACSima™ imaging platform: A pilot study. [PDF]
Acta Neuropathol CommunSciacco M +9 more
europepmc +1 more source
A Rare Case of Anti-HMGCR-Positive Immune-Mediated Necrotizing Myopathy Associated With Statin Use. [PDF]
CureusOkoli ML +5 more
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ZCCHC4 Orchestrates Hepatocellular Carcinoma Metastasis by Regulating Lipid biosynthesis and TMEM97/LCN2/Twist1 Pathway. [PDF]
Int J Biol SciYe J +14 more
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Anti-HMGCR and anti-DFS70 antibodies immunofluorescence patterns
Autoimmunity Reviews, 2017We have replicated the findings of Alvarado-Cardenas et al. in our cohort of anti-HMGCR myositis patients, confirming the high specificity and sensibility of the rat liver IF pattern, especially when compared to the previously reported HEp-2 anti-HMGCR pattern.
Daniele Cammelli +2 more
exaly +3 more sources
Immunologic Research, 2016
Anti-HMGCR antibodies represent a characteristic serological feature of statin-exposed and statin-unexposed patients with immune-mediated necrotizing myopathy (IMNM). We assessed anti-HMGCR antibodies in patients with suspected IMNM following statin exposure and patients with other autoimmune rheumatic diseases.
Miri Blank, M Mahler
exaly +3 more sources
Anti-HMGCR antibodies represent a characteristic serological feature of statin-exposed and statin-unexposed patients with immune-mediated necrotizing myopathy (IMNM). We assessed anti-HMGCR antibodies in patients with suspected IMNM following statin exposure and patients with other autoimmune rheumatic diseases.
Miri Blank, M Mahler
exaly +3 more sources
Cutaneous involvement in anti-HMGCR positive necrotizing myopathy [PDF]
Journal of Autoimmunity, 2021 OBJECTIVE Anti-3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) positive immune-mediated necrotizing myopathy (IMNM) is a rare disease. It is induced by exogenous substances, most often by statins. Little is known about cutaneous manifestations
Laurence Feldmeyer +2 more
exaly +3 more sources
Rheumatology International
Statin-induced immune-mediated necrotizing myopathy (IMNM) is a rare systemic neuromuscular condition. We present a case of a patient with a severe phenotype of the disease that was found to have an increase in anti-HMGCR and anti-ACHR antibodies. A potential association between these antibodies have not been previously described.
Sanjeev Herr, Razmig Garabet
exaly +3 more sources
Statin-induced immune-mediated necrotizing myopathy (IMNM) is a rare systemic neuromuscular condition. We present a case of a patient with a severe phenotype of the disease that was found to have an increase in anti-HMGCR and anti-ACHR antibodies. A potential association between these antibodies have not been previously described.
Sanjeev Herr, Razmig Garabet
exaly +3 more sources
Rheumatology International, 2022 This study aimed to determine the prevalence and clinical characteristics of anti-HMGCR antibodies in idiopathic inflammatory myositis (IIM) at a tertiary care centre in northern India.
Ritu Verma, Arvind Nune, Vikas Agarwal
exaly +2 more sources
CHARACTERISATION OF UK ANTI-HMGCR+ ANTIBODY ASSOCIATED MYOSITIS
Journal of Neurology, Neurosurgery & Psychiatry, 2016Introduction Anti-HMG-CoA Reductase (anti-HMGCR) antibodies are associated with an immune-mediated necrotising myopathy related to previous ‘statin’ use. The role of this antibody in pathogenesis is incompletely understood. We have thoroughly characterised a cohort of anti-HMGCR associated myositis patients to increase understanding of the role of ...
Murphy, Sean +8 more
openaire +3 more sources