Results 71 to 80 of about 2,269,213 (187)
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest +3 more
wiley +1 more source
CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems
The FEBS Journal, EarlyView.Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén +11 more
wiley +1 more source
Medicina Clínica PrácticaResumen: La miositis necrosante autoinmune (MNA) asociada al uso de estatinas es una entidad poco frecuente, caracterizada por debilidad muscular proximal progresiva, elevación marcada y persistente de la creatinfosfoquinasa y presencia de ...
Luis Ángel Rodríguez-Chávez +3 more
doaj +1 more source
Arthritis Research & Therapy, 2017 Background Cancer is a significant complication contributing to increased mortality in idiopathic inflammatory myopathies (IIMs), and the association between IIMs and cancer has been extensively reported.
Hanbo Yang +9 more
doaj +1 more source
Journal of Periodontal Research, EarlyView.This systematic review evaluated drug‐target Mendelian randomisation studies on periodontitis. Twelve studies identified host‐response‐related targets mainly involved in inflammatory, complement, and immune pathways. Although some targets were linked to existing drugs, the evidence remains preliminary and heterogeneous, requiring replication and ...
Luigi Nibali +4 more
wiley +1 more source
Two Cases of Statin-Induced Immune-Mediated Necrotizing Myopathy: A Rare Side Effect of Statins
RheumatoStatins are effective drugs for lowering cholesterol and reducing cardiovascular risk. Rarely, they can trigger autoimmune myopathies like immune-mediated necrotizing myopathy (IMNM), associated with anti-HMGCR antibodies.
Luis Angel Montero Furelos +2 more
doaj +1 more source
MedComm, Volume 7, Issue 10, October 2026.• EThcD‐sceHCD‐MS/MS and updated PANDA software decode IgG N‐glycosylation in IIMs. • Unsupervised clustering reveals three novel glyco‐endotypes matching clinical phenotypes. • A seven‐glycopeptide model enables robust endotype prediction beyond conventional subtypes.
Tong Wu +9 more
wiley +1 more source
The Utility of serological markers in inflammatory bowel diseases: Gadget or magic? [PDF]
, 2008 The panel of serologic markers for inflammatory bowel diseases (IBD) is rapidly expanding. Anti–Saccharomyces cerevisiae antibodies (ASCA) and atypical perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) remain the most widely investigated ...
Papp, Mária +3 more
core
MedComm, Volume 7, Issue 10, October 2026.CH25H deficiency permits optimal dendritic cell activation following BCG exposure, characterized by increased IL‐12p70 production. In vivo, CH25H deficiency promotes enhanced BCG‐mediated protection and sustained IL‐2 producing T cell response. ABSTRACT Bacillus Calmette‐Guérin (BCG) remains the only licensed vaccine for tuberculosis (TB), yet its ...
Hagyu Kim +6 more
wiley +1 more source
Anti-retinal Antibodies in Sarcoidosis
, 2022 To measure, characterize, and evaluate the clinical significance of anti-retinal antibodies in patients with sarcoid uveitis. Prospective study of anti-retinal antibodies in 45 patients with biopsy-proven sarcoidosis (25 with and 20 without uveitis ...
Juan Martin García-Sancho (13962149) +8 more
core +1 more source