Broken drug markets in infectious diseases: Opportunities outside the private sector? [PDF]
PLoS Neglected Tropical Diseases, 2019 A subset of anti-infective drugs are increasingly unavailable for patients in the United States due to pricing or withdrawal from the market. Timely market solutions are needed.
Jonathan D Alpern +2 more
doaj +1 more source
Strategies to prevent the occurrence of resistance against antibiotics by using advanced materials [PDF]
, 2018 This is a post-peer-review, pre-copyedit version of an article published in Applied microbiology and biotechnology The final authenticated version is available online at: http://dx.doi.org/10.1007/s00253-018-8776-0Drug resistance occurrence is a global ...
Bassegoda Puigdomenech, Arnau +3 more
core +2 more sources
A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae [PDF]
, 2013 The aim of this study was to explore the mechanisms of resistance against invading Ascaris suum larvae in pigs. Pigs received a low dose of 100 A. suum eggs daily for 14 weeks.
Chiers, Koen +6 more
core +10 more sources
Evaluation of Antimicrobial Efficacy of Modified Novel Double Antimicrobial Preparations Against E.Faecalis and C. Albicans: An In-vitro Study [PDF]
Journal of Clinical and Diagnostic ResearchIntroduction: The aim of endodontic treatment is the reduction of microbial load inside the root canal, for which Calcium hydroxide {Ca(OH)2} is the most commonly used medicament, which is ineffective against resistant microbes such as E.faecalis and C ...
N Meena +4 more
doaj +1 more source
Liposomes used in the delivery of various antimicrobials to biofilm-producing infections: a systematic review [PDF]
Nanomedicine JournalObjective(s): Persistent clinical infections have driven extensive research to find effective solutions. Liposomes, known for their biocompatibility, versatility, targetability, and tunability, have emerged as a prominent drug delivery system.
Manouchehr Teymouri +7 more
doaj +1 more source
Cerebrovascular complications and infective endocarditis. impact of available evidence on clinical outcome [PDF]
, 2018 Infective endocarditis (IE) is a life-threatening disease. Its epidemiological profile has substantially changed in recent years although 1-year mortality is still high.
De Bellis, Antonio +8 more
core +1 more source
Synthesis and characterization of anti-infective agents
Journal of Applied Pharmaceutical Research, 2019 Antifungal chemotherapy depends on bio-chemical alterations between fungi and mammals. Unlike bacteria, which are prokaryotes, both fungi and mammals are eukaryotes and the biochemical differences between them are not significant. However, there are some
Monika Sharma +5 more
doaj +1 more source
Most of the response elicited against Wolbachia surface protein in filarial nematode infection is due to the infective larval stage [PDF]
, 2004 Immune responses to the intracellular Wolbachia bacteria of filarial nematodes are thought to contribute to the pathologic process of filarial infection.
Allen, Judith E +7 more
core +1 more source
Pharmacodynamic modelling of in vitro activity of tetracycline against a representative, naturally occurring population of porcine Escherichia coli [PDF]
, 2015 Background The complex relationship between drug concentrations and bacterial growth rates require not only the minimum inhibitory concentration but also other parameters to capture the dynamic nature of the relationship.
Agersø, Yvonne +9 more
core +4 more sources
Prevalence and antimicrobial susceptibility of Escherichia coli O157 in beef at butcher shops and restaurants in central Ethiopia [PDF]
, 2017 Background: Ethiopia bears the largest burden of foodborne diseases in Africa, and diarrheal diseases are the second leading causes of premature deaths.
Beyene, Takele +12 more
core +5 more sources